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United States ( Change Country )
GSK1292263 Chemical Structure
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Biological Activity
GSK1292263 is a novel GPR119 receptor agonist used for the treatment of type 2 diabetes. In the intravenous glucose tolerance test, significant increases in the peak insulin response and insulin AUC(0-15 min) of 30-60% were reported in the GSK1292263 treatment group, compared with values in the vehicle control cohort. This insulin upregulation correlated with a significant increase in the glucose disposal rate. [1][2]
References on GSK1292263
- [1] http://professional.diabetes.org/News_Display.aspx?CID=82333&TYP=9 ;
- [2] http://clinicaltrials.gov/ct2/show/NCT01101568 ;
Chemical Information
| Molecular Weight (WM): | 456.56 |
|---|---|
| Formula: | C23H28N4O4S |
| CAS No.: | 1032823-75-8 |
| Synonyms: |
N/A
|
| Dissolve in (25°C): | DMSO ≥23mg/mL |
| Water <1mg/mL | |
| Ethanol ≥2mg/mL | |
| Storage: | 2 years-20°CPowder |
| 1 week-4°Cin DMSO | |
| 1 month-80°in DMSO |
Quality Control & MSDS
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