Product Use Citations
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Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability
Science, 2016,351(6277):aad3680
Anti-cancer Compound Library purchased from Selleck.
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Nuclear envelope rupture and repair during cancer cell migration
KU-55933 purchased from Selleck.
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A PGC1α-mediated transcriptional axis suppresses melanoma metastasis
Nature, 2016,10.1038/nature19347
Vemurafenib (PLX4032, RG7204), PD98059, Selumetinib (AZD6244) and PF-573228 purchased from Selleck.
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Dual targeting of p53 and c-MYC selectively eliminates leukaemic stem cells
Nilotinib (AMN-107) and Dasatinib purchased from Selleck.
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Structural basis of Smoothened regulation by its extracellular domains
Vismodegib (GDC-0449) purchased from Selleck.
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Potentiating the antitumour response of CD8(+) T cells by modulating cholesterol metabolism
Avasimibe purchased from Selleck.
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Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function
Raltegravir (MK-0518) purchased from Selleck.
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Derivation and differentiation of haploid human embryonic stem cells
CHIR-99021 (CT99021) and IWP-2 purchased from Selleck.
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Functional Genomic Landscape of Human Breast Cancer Drivers, Vulnerabilities, and Resistance
Everolimus (RAD001) purchased from Selleck.
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Exploiting Temporal Collateral Sensitivity in Tumor Clonal Evolution
Vandetanib (ZD6474) purchased from Selleck.
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An alternative pluripotent state confers interspecies chimaeric competency.
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A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria.
Nature, 2015, 520(7549):683-687.
Wortmannin and LY294002 purchased from Selleck.
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Therapy-induced tumour secretomes promote resistance and tumour progression.
Nature, 2015, 520(7547):368-372.
Vemurafenib purchased from Selleck.
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A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol.
Nature, 2015, 519(7543):370-373.
AG-14361 purchased from Selleck.
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Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex.
Nature, 2015, 517(7536):583-588.
PLX-4720 purchased from Selleck.
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Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination.
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Endophilin marks and controls a clathrin-independent endocytic pathway.
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An ERK/Cdk5 axis controls the diabetogenic actions of PPARү.
Nature, 2015, 517(7534):391-395.
GSK1120212 and PD0325901 purchased from Selleck.
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Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia.
Nature, 2015, 521(7552):357-361.
PRT062607 purchased from Selleck.
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Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair.
Nature, 2015, 518(7538):258-262.
AG-014699 purchased from Selleck.
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MET is required for the recruitment of anti-tumoural neutrophils.
Nature, 2015, 10.1038/nature14407.
JNJ-38877605 purchased from Selleck.
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Mechanical induction of the tumorigenic β-catenin pathway by tumour growth pressure.
Nature, 2014, 10.1038/nature14329.
Vandetanib and Ponatinib purchased from Selleck.
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REV7 counteracts DNA double-strand break resection and affects PARP inhibition.
Nature, 2015, 10.1038/nature14328.
KU-55933 purchased from Selleck.
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Epicardial regeneration is guided by cardiac outflow tract and Hedgehog signalling.
Nature, 2013, 10.1038/nature14325.
Cyclopamine purchased from Selleck.
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Pathological axonal death through a MAPK cascade that triggers a local energy deficit.
PLX-4720, PD-0325901, MK-2206 and GDC-0068 purchased from Selleck.
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