- NAMPT Inhibitors (3)
|Catalog No.||Information||Product Use Citations||Product Validations|
STF-118804 is a highly specific NAMPT inhibitor.
RSV-induced SIRT1 expression is PARP1-dependent in PC12 cells. a, PC12 cells were pretreated with STF-118804 (100 nM) for 1 h prior to treatment with RSV (20 lM) for another 2 h, followed by treatment with or without of Ab25–35 (30 lM) for an additional 24 h. SIRT1 expression was determined by western blot analysis. b, The bar graph shows the quantification of endogenous SIRT1. c, Cells were treated with various concentrations (1, 5, 10, and 20 lM) of RSV for 24 h. PARP1 expression was detected by western blot analysis.
P7C3 is a potent proneurogenic and neuroprotective chemical that targets NAMPT enzyme.
GMX1778 (CHS828) is a potent and specific inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) with IC50 and Kd of < 25 nM and 120 nM, respectively. Phase 1.