Hippo pathway

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S1786 Verteporfin <1 mg/mL 100 mg/mL <1 mg/mL
S8334 XMU-MP-1 <1 mg/mL 83 mg/mL 1 mg/mL
S8554 Super-TDU 100 mg/mL -1 mg/mL -1 mg/mL
S8164 YAP-TEAD Inhibitor 1 (Peptide 17) 100 mg/mL -1 mg/mL -1 mg/mL
Catalog No. Information Product Use Citations Product Validations
S1786

Verteporfin

Verteporfin is a small molecule that inhibits TEAD–YAP association and YAP-induced liver overgrowth. It is also a potent second-generation photosensitizing agent derived from porphyrin.

S8334New

XMU-MP-1

XMU-MP-1 is an inhibitor of MST1/2 with IC50 values of 71.1±12.9 nM and 38.1±6.9 nM against MST1 and MST2, respectively.

S8554New

Super-TDU

Super-TDU is an inhibitory peptide targeting YAP-TEADs interaction.

S8164

YAP-TEAD Inhibitor 1 (Peptide 17)

Peptide 17 is a inhibitor of this YAP-TEAD protein-protein interaction which has potential usage in treatment of YAP-involved cancers with IC50 of 25nM.

Tags: Hippo signaling pathway | Hippo pathway | Hippo pathway inhibitor review