BMI-1

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S7372 PTC-209 <1 mg/mL 99 mg/mL <1 mg/mL
S5315 PRT4165 <1 mg/mL 11 mg/mL 4 mg/mL
S7539 PTC-209 HBr <1 mg/mL 100 mg/mL <1 mg/mL
S8662 PTC-028 <1 mg/mL 81 mg/mL 17 mg/mL
Catalog No. Information Product Use Citations Product Validations
S7372

PTC-209

PTC-209 is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM in HEK293T cell line, and results in irreversible reduction of cancer-initiating cells (CICs).

S5315New

PRT4165

PRT4165 is a Bmi1/Ring1A inhibitor with an IC50 of 3.9 µM in the cell-free assay and also inhibits PRC1-mediated H2A ubiquitylation in vivo and in vitro.

S7539

PTC-209 HBr

PTC-209 HBr is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in irreversible reduction of cancer-initiating cells (CICs).

S8662New

PTC-028

PTC-028 is an orally bioavailable compound that decreases BMI-1 levels by posttranslational modification.

Tags: BMI-1 inhibitor | BMI-1 modulator | BMI-1 chemical