Adenosine Receptor

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S2790 Istradefylline <1 mg/mL 6 mg/mL <1 mg/mL
S2153 CGS 21680 HCl <1 mg/mL 107 mg/mL <1 mg/mL
S8105 ZM241385 <1 mg/mL 67 mg/mL <1 mg/mL
S8314 5-Iodotubercidin <1 mg/mL 78 mg/mL <1 mg/mL
S8104 SCH58261 <1 mg/mL 69 mg/mL <1 mg/mL
S7588 Reversine <1 mg/mL 5 mg/mL <1 mg/mL
Catalog No. Information Product Use Citations Product Validations
S8105New

ZM241385

ZM-241385 is a high affinity antagonist ligand selective for the adenosine A2A receptor.

S8314New

5-Iodotubercidin

5-Iodotubercidin is a potent adenosine kinase inhibitor with IC50 of 26 nM. It inhibits nucleoside transporter, CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2 and PKC.

S8104

SCH58261

SCH 58261 is a potent and selective A2a adenosine receptor antagonist with Ki of 2.3 nM and 2 nM for rat A2a and bovine A2a, respectively.

S2153

CGS 21680 HCl

CGS 21680 HCl is an adenosine A2 receptor agonist with IC50 of 22 nM, exhibits 140-fold over A1 receptor.

S2790

Istradefylline

Istradefylline is a selective adenosine A2A receptor (A2AR) antagonist with Ki of 2.2 nM. Phase 3.

S7588

Reversine

Reversine is a potent human A3 adenosine receptor antagonist with Ki of 0.66 μM, and a pan-aurora A/B/C kinase inhibitor with IC50 of 12 nM/13 nM/20 nM, respectively. Also used for stem cell dedifferentiation.

Catalog No. Information Product Use Citations Product Validations
S8105New

ZM241385

ZM-241385 is a high affinity antagonist ligand selective for the adenosine A2A receptor.

S8314New

5-Iodotubercidin

5-Iodotubercidin is a potent adenosine kinase inhibitor with IC50 of 26 nM. It inhibits nucleoside transporter, CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2 and PKC.

S8104

SCH58261

SCH 58261 is a potent and selective A2a adenosine receptor antagonist with Ki of 2.3 nM and 2 nM for rat A2a and bovine A2a, respectively.

Catalog No. Information Product Use Citations Product Validations
S2790

Istradefylline

Istradefylline is a selective adenosine A2A receptor (A2AR) antagonist with Ki of 2.2 nM. Phase 3.

2015, 27(3):229-45

S7588

Reversine

Reversine is a potent human A3 adenosine receptor antagonist with Ki of 0.66 μM, and a pan-aurora A/B/C kinase inhibitor with IC50 of 12 nM/13 nM/20 nM, respectively. Also used for stem cell dedifferentiation.

2015, 522(7557):492-6

2013, 80(7):522-34

Catalog No. Information Product Use Citations Product Validations
S2153

CGS 21680 HCl

CGS 21680 HCl is an adenosine A2 receptor agonist with IC50 of 22 nM, exhibits 140-fold over A1 receptor.

2016, 289(1):109-16