OX Receptor

Sigaling Pathway Map

Research Area

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S7585 SB-334867 <1 mg/mL 63 mg/mL 3 mg/mL
S3054 Alverine Citrate <1 mg/mL 95 mg/mL <1 mg/mL
S1545 SB408124 <1 mg/mL 36 mg/mL <1 mg/mL
S2160 Almorexant HCl <1 mg/mL 72 mg/mL 51 mg/mL

Isoform-specific Inhibitors

Catalog No. Information Product Use Citations Product Validations
S3054

Alverine Citrate

Alverine citrate is a drug used for functional gastrointestinal disorders.

S7585

SB-334867

SB-334867 is a selective orexin-1 (OX1) receptor antagonist.

S1545

SB408124

SB408124 is a non-peptide antagonist for OX1 receptor with Ki of 57 nM and 27 nM in both whole cell and membrane, respectively, exhibits 50-fold selectivity over OX2 receptor.

S2160

Almorexant HCl

Almorexant HCl is an orally active, dual orexin receptor antagonist with IC50 of 6.6 nM and 3.4 nM for OX1 and OX2 receptor, respectively. Phase 3.

Catalog No. Information Product Use Citations Product Validations
S7585

SB-334867

SB-334867 is a selective orexin-1 (OX1) receptor antagonist.

S1545

SB408124

SB408124 is a non-peptide antagonist for OX1 receptor with Ki of 57 nM and 27 nM in both whole cell and membrane, respectively, exhibits 50-fold selectivity over OX2 receptor.

S2160

Almorexant HCl

Almorexant HCl is an orally active, dual orexin receptor antagonist with IC50 of 6.6 nM and 3.4 nM for OX1 and OX2 receptor, respectively. Phase 3.

2016, 358(3):492-501

Catalog No. Information Product Use Citations Product Validations
S3054

Alverine Citrate

Alverine citrate is a drug used for functional gastrointestinal disorders.