Liver X Receptor

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S2630 GW3965 HCl <1 mg/mL 16 mg/mL <1 mg/mL
S7076 T0901317 <1 mg/mL 96 mg/mL 96 mg/mL
S7934 SR9243 <1 mg/mL <1 mg/mL <1 mg/mL
S8390 LXR-623 (WAY-252623) <1 mg/mL 84 mg/mL 84 mg/mL
Catalog No. Information Product Use Citations Product Validations
S8390New

LXR-623 (WAY-252623)

LXR-623 is a novel liver X-receptor(LXR) agonist with IC50 values of 179 nM and 24 nM for LXR-α and LXR-β, respectively. It is orally bioavailable and readily passes the blood-brain barrier.

S7934

SR9243

SR9243 is a potent and selective LXR inverse agonist.

S2630

GW3965 HCl

GW3965 HCl is a potent, selective LXR agonist for hLXRα and hLXRβ with EC50 of 190 and 30 nM in cell-free assays, respectively.

S7076

T0901317

T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively.

Catalog No. Information Product Use Citations Product Validations
S8390New

LXR-623 (WAY-252623)

LXR-623 is a novel liver X-receptor(LXR) agonist with IC50 values of 179 nM and 24 nM for LXR-α and LXR-β, respectively. It is orally bioavailable and readily passes the blood-brain barrier.

Catalog No. Information Product Use Citations Product Validations
S2630

GW3965 HCl

GW3965 HCl is a potent, selective LXR agonist for hLXRα and hLXRβ with EC50 of 190 and 30 nM in cell-free assays, respectively.

2015, 589(1):52-8

2016, 161(9):2491-501

S7076

T0901317

T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively.

2015, 589(1):52-8

2017, 12(1):322

Catalog No. Information Product Use Citations Product Validations
S7934

SR9243

SR9243 is a potent and selective LXR inverse agonist.