| S4067 |
Deferiprone
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Deferiprone (CP20) is a chelating agent with an affinity for ferric ion (iron III),binds with ferric ions to form neutral 3:1 (deferiprone:iron) complexes that are stable over a wide range of pH values.
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Redox Biol, 2025, 85:103739
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bioRxiv, 2025, 2025.07.10.663832
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Cancer Lett, 2024, 592:216898
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| S6828 |
Cremophor EL
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Cremophor EL, a polyethoxylated surfactant, is a formulation vehicle used for various poorly-water soluble drugs, including the anticancer agent paclitaxel (Taxol). This compound is used in severe anaphylactoid hypersensitivity reactions, hyperlipidaemia, abnormal lipoprotein patterns, aggregation of erythrocytes and peripheral neuropathy.
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Chinese Medicine, November 14 2025, 189
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Aging and disease, May 20 2024, 1120-1140
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Frontiers in Oncology, July 05 2022, 936145
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| S2487 |
Mycophenolic Acid (Mycophenolate, MPA)
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Mycophenolic acid (Mycophenolate, RS-61443) is a potent IMPDH inhibitor and the active metabolite of an immunosuppressive drug, used to prevent rejection in organ transplantation.
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Cancers, October 21, 2025, 3389
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Antiviral Research, October 2017, 76-85
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Journal of Immunotoxicology, December 15, 2021, 154-162
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| S7828 |
Licochalcone A
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Licochalcone A is an estrogenic flavanoid extracted from licorice root, showing antimalarial, anticancer, antibacterial and antiviral activities. Phase 3.
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European Journal of Pharmacology, October 15, 2023, 176031
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BioMed Research International, March 10, 2022, 5687832
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Oncology Reports, December 14, 2017, 1181-1190
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| S3608 |
Demethylzeylasteral (T-96)
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An active component isolated from Tripterygium wilfordii Hook F., Demethylzeylasteral (T-96) inhibits UDP-glucuronosyltransferase (UGT) isoforms UGT1A6 and UGT2B7 with immunosuppressive effects.
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J Cancer, 2025, 16(1):227-240
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南京中医药大学学报, 2025, nan
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J Cancer, 2021, 12(13):3967-3975
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| S3018 |
Niflumic acid
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Niflumic acid (Nifluril) is an inhibitor of cyclooxygenase-2 used for joint and muscular pain.
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Oncol Lett, 2020, 20(4):39
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Oncology Letters, 2020, 39
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| S0931 |
Jaceosidin
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Jaceosidin, a flavonoid isolated from Artemisia vestita, possesses anti-tumor and anti-proliferative activities in many cancer cells. This compound induces apoptosis, activates Bax and down-regulates Mcl-1 and c-FLIP expression. It also inhibits COX-2 expression and NF-κB activation.
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