RNR antagonist | RNR inhibitor | RNR agonist

Not only can you personalize your library with chemicals from within Selleck’s inventory, but we can also purchase chemicals from other companies and integrate them into your custom library. Build the right library for your research endeavors by choosing from compounds in all of our available libraries.

Please contact us at [email protected] to customize your library.

You could select:

Specific Compounds Quantities 96 or 384 well Plate Map Dry/solid or DMSO solution

Antibodies

InVivo Antibodies

Therapeutic Antibodies

Bioreagents

qPCR: 2x SYBR Green qPCR Master Mix; 2x SYBR Green qPCR Master Mix(Low ROX); 2x SYBR Green qPCR Master Mix(High ROX)

Protein Assay: Protein A/G Magnetic Beads for IP; Anti-Flag magnetic beads; Anti-Flag Affinity Gel; Anti-Myc magnetic beads; Anti-HA magnetic beads; Magnetic Separator; Poly FLAG Peptide lyophilized powder

Protease Inhibitor Cocktail: Protease Inhibitor Cocktail (EDTA-Free, 100X in DMSO); Phosphatase Inhibitor Cocktail (2 Tubes, 100X)

Cell Biology: Cell Counting Kit-8 (CCK-8)

Animal Experiment: Mouse Direct PCR Kit (For Genotyping)

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Catalog No.	Product Name	Information	Product Use Citations
S0283	COH-29	COH29 (RNR Inhibitor COH29) is a potent inhibitor of ribonucleotide reductase (RNR) with anticancer activity. COH29 (RNR Inhibitor COH29) inhibits recombinant RNR small subunit (RRM1/RRM2) activity in vitro with IC50 of 16 μM.	Adv Sci (Weinh), 2021, e2100881
S1218	Clofarabine	Clofarabine (Clolar) inhibits the enzymatic activities of ribonucleotide reductase (RNR) (IC50 = 65 nM) and DNA polymerase. Clofarabine induces autophagy and apoptosis.	Hum Cell, 2021, 10.1007/s13577-021-00579-z Hum Cell, 2021, 10.1007/s13577-021-00639-4 iScience, 2021, 24(9):103080
S3641	Osalmid	Osalmid suppresses ribonucleotide reductase (RNR) activity in a concentration-dependent manner, with a 50% RR activity-inhibitory concentration (IC50) of 8.23 μM.
S7470	Triapine	Triapine (3-AP) is a potent ribonucleotide reductase (RNR) inhibitor with broad spectrum antitumor activity by inhibiting DNA synthesis. Phase 2.	Cell, 2021, 184(2):334-351.e20 Mol Cancer, 2021, 20(1):97 Sci Rep, 2021, 11(1):13474
S0283	COH-29	COH29 (RNR Inhibitor COH29) is a potent inhibitor of ribonucleotide reductase (RNR) with anticancer activity. COH29 (RNR Inhibitor COH29) inhibits recombinant RNR small subunit (RRM1/RRM2) activity in vitro with IC50 of 16 μM.	Adv Sci (Weinh), 2021, e2100881
S1218	Clofarabine	Clofarabine (Clolar) inhibits the enzymatic activities of ribonucleotide reductase (RNR) (IC50 = 65 nM) and DNA polymerase. Clofarabine induces autophagy and apoptosis.	Hum Cell, 2021, 10.1007/s13577-021-00579-z Hum Cell, 2021, 10.1007/s13577-021-00639-4 iScience, 2021, 24(9):103080
S3641	Osalmid	Osalmid suppresses ribonucleotide reductase (RNR) activity in a concentration-dependent manner, with a 50% RR activity-inhibitory concentration (IC50) of 8.23 μM.
S7470	Triapine	Triapine (3-AP) is a potent ribonucleotide reductase (RNR) inhibitor with broad spectrum antitumor activity by inhibiting DNA synthesis. Phase 2.	Cell, 2021, 184(2):334-351.e20 Mol Cancer, 2021, 20(1):97 Sci Rep, 2021, 11(1):13474

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