Home DNA Damage/DNA Repair RNR

RNR

Other DNA Damage/DNA Repair Related Inhibitors

HDAC PARP WRN Sirtuin Topoisomerase Telomerase DNA/RNA Synthesis MTH1 DNA alkylator High-mobility Group
Cat.No. Product Name Information Product Use Citations Product Validations
S1218 Clofarabine Clofarabine (Clolar) inhibits the enzymatic activities of ribonucleotide reductase (RNR) (IC50 = 65 nM) and DNA polymerase. Clofarabine induces autophagy and apoptosis.
Investigative Ophthalmology & Visual Science, 2025, 42
Invest Ophthalmol Vis Sci, 2025, 66(5):42
bioRxiv, 2025, 2025.04.25.650475
Verified customer review of Clofarabine
S0283 COH-29 COH29 (RNR Inhibitor COH29) is a potent inhibitor of ribonucleotide reductase (RNR) with anticancer activity. COH29 (RNR Inhibitor COH29) inhibits recombinant RNR small subunit (RRM1/RRM2) activity in vitro with IC50 of 16 μM.
Adv Sci (Weinh), 2021, e2100881
Advanced Science, 2021, e2100881
S3385 NSAH NSAH (HNASH) is a reversible and competitive nonnucleoside ribonucleotide reductase (RNR) inhibitor, with cell-free IC50 of 32 μM and cell-based IC50 of ~250 nM, respectively.
Pharmaceutics, 2022, 14-71387
S7470 Triapine (3-AP) Triapine (3-AP) is a potent ribonucleotide reductase (RNR) inhibitor with broad spectrum antitumor activity by inhibiting DNA synthesis. Phase 2.
Anticancer Research, June 2021, 2795-2804
OncoTargets and Therapy, April 2019, 3267-3275
iScience, 2024, 27(10):110862
Verified customer review of Triapine (3-AP)
S3641 Osalmid Osalmid suppresses ribonucleotide reductase (RNR) activity in a concentration-dependent manner, with a 50% RR activity-inhibitory concentration (IC50) of 8.23 μM.
Cell Commun Signal, 2026, 24(1)216