Home DNA Damage/DNA Repair High-mobility Group

High-mobility Group

Other DNA Damage/DNA Repair Related Inhibitors

HDAC PARP WRN Sirtuin Topoisomerase Telomerase DNA/RNA Synthesis MTH1 DNA alkylator CRISPR/Cas9

Isoform-selective Products

Cat.No. Product Name Information Product Use Citations Product Validations
S2302 Glycyrrhizin (Glycyrrhizic Acid, NSC 167409) Glycyrrhizin (NSC 167409, Glycyrrhizic Acid) is a direct HMGB1(high mobility group box 1) inhibitor that inhibits HMGB1-dependent inflammatory molecule expression and oxidative stress; modulates P38 and P-JNK but not p-ERK signalling; Also inhibits 11 beta-hydroxysteroid dehydrogenase and monoamine oxidase (MAO).
Nat Commun, 2025, 16(1):2513
Chin Med J (Engl), 2025, 138(1):79-92
Oncol Rep, 2025, 54(3)106
Verified customer review of Glycyrrhizin (Glycyrrhizic Acid, NSC 167409)
S2376 Ammonium Glycyrrhizinate Ammonium Glycyrrhizinate (AMGZ, Glycyram, Glycyrrhizin ammonium salt, Glycyrrhizic acid ammonium salt) is a unique product from Licorice root with a very high sweetness. This compound is a direct inhibitor of HMGB1 with anti-inflammatory, anti-tumor, anti-diabetic activities. It inhibits growth and cytopathology of several unrelated DNA and RNA viruses. This chemical also inhibits both hepatic delta 4-5-reductase and 11 beta-hydroxysteroid dehydrogenase.
Nat Commun, 2025, 16(1):2513
Eur J Pharmacol, 2024, 962:176171
Pharmacol Res, 2023, 192:106791