Zeaxanthin

Zeaxanthin, the carotenoid alcohol participates in the xanthophyll cycle, activates the extrinsic apoptosis pathway which induces apoptosis on uveal melanoma cells with IC50 value 40.8 µM.

Zeaxanthin Chemical Structure

Zeaxanthin Chemical Structure

CAS: 144-68-3

Purity & Quality Control

Batch: S324301 CHCl3] 4 mg/mL] false] DMSO] Insoluble] false] Water] Insoluble] false Purity: 98.04%
98.04

Zeaxanthin Related Products

Signaling Pathway

Choose Selective Bcl-2 Inhibitors

Biological Activity

Description Zeaxanthin, the carotenoid alcohol participates in the xanthophyll cycle, activates the extrinsic apoptosis pathway which induces apoptosis on uveal melanoma cells with IC50 value 40.8 µM.
Targets
Bcl-2 [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05283941 Recruiting
Macular Degeneration|Retinal Degeneration|Retinal Diseases|Eye Diseases
Tufts University|American Pistachio Growers
June 10 2022 Not Applicable
NCT05267522 Completed
Hypercholesterolemia|Hyperlipidemias|Physical Inactivity|Diet Healthy
University of South Australia|American Egg Board
March 1 2022 Not Applicable
NCT04779398 Completed
Age Related Macular Degeneration
The University of Queensland
September 25 2020 --

Chemical Information & Solubility

Molecular Weight 568.87 Formula

C40H56O2

CAS No. 144-68-3 SDF --
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

CHCl3 : 4 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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