CAS No. 144-68-3
Batch:
Purity:98.04
Chemical Structure
Check the
Zeaxanthin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (1R)-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4R)-4-hydroxy-2,6,6-trimethylcyclohexen-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethylcyclohex-3-en-1-ol | |
|---|---|---|
| CAS Number | 144-68-3 | |
| Molecular Formula |
C40H56O2 |
|
| Molecular Weight (MW) | 568.87 | |
| InChIKey | JKQXZKUSFCKOGQ-QAYBQHTQSA-N |
Zeaxanthin is a natural carotenoid alcohol involved in the xanthophyll cycle that activates the extrinsic apoptosis pathway, exhibiting antiproliferative activity against human uveal melanoma cells with an IC50 of 40.8 µM. Treatment leads to the activation of caspase-8 and caspase-3, cleavage of PARP, and downstream induction of apoptotic cell death in melanoma models. [1]
|
Concentration
Volume
Mass
|
1 mg | 5 mg | 10 mg |
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| CHCl3 | 4 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.