Scopolamine

Catalog No.S9326 Synonyms: Skopolamin

For research use only.

Scopolamine (Skopolamin) is a tropane alkaloid derived from plants of the nightshade family, specifically Hyoscyamus niger and Atropa belladonna, with anticholinergic, antiemetic and antivertigo properties.

Scopolamine Chemical Structure

CAS No. 51-34-3

Purity & Quality Control

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Biological Activity

Description Scopolamine (Skopolamin) is a tropane alkaloid derived from plants of the nightshade family, specifically Hyoscyamus niger and Atropa belladonna, with anticholinergic, antiemetic and antivertigo properties.

Protocol (from reference)

Chemical Information

Molecular Weight 303.35
Formula

C17H21NO4

Density 1.31 g/mL
CAS No. 51-34-3
Storage 2 years -20°C liquid
Smiles CN1C2CC(CC1C3C2O3)OC(=O)C(CO)C4=CC=CC=C4

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04999449 Not yet recruiting Drug: Scopolamine|Drug: Placebo Scopolamine|Motion Sickness Dartmouth-Hitchcock Medical Center August 2022 Phase 1
NCT04314713 Terminated Drug: Scopolamine Hydrobromide Trihydrate Scopolamine Causing Adverse Effects in Therapeutic Use Battelle Memorial Institute June 2 2020 Phase 1
NCT03874130 Unknown status Drug: Scopolamine Major Depressive Disorder (MDD) Repurposed Therapeutics Inc. August 1 2018 Phase 1
NCT03294109 Completed Drug: Abdominal wall block with liposomal bupivicaine Pain Postoperative|Analgesics Opioid|Analgesics Non-Narcotic|Physiological Effects of Drugs|Peripheral Nervous System Agents|Patient Satisfaction|Return to Work|Activity Sexual University of California Los Angeles January 1 2018 Phase 4
NCT03131050 Completed Drug: Scopolamine|Drug: Escitalopram|Drug: Saline Major Depressive Disorder Capital Medical University March 15 2017 Phase 4

(data from https://clinicaltrials.gov, updated on 2022-08-01)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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