research use only

RBN013209 CD markers inhibitor

Name: RBN013209
Brand: Selleck Chemicals
SKU: E1305
Availability: InStock
Rating: 5 (1 reviews)

Cat.No.E1305

RBN013209 is a potent inhibitor of CD38 with an IC50 of 0.01-0.1 μM for human CD38. It can be used for the research of cancer.

Chemical Structure

Molecular Weight: 384.43

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Quality Control

Batch: E130501 DMSO]19 mg/mL]false]Water]Insoluble]false]Ethanol]Insoluble]false Purity: 99.00%

Cited in Nature Medicine for its top-tier quality
COA
HPLC
SDS
Datasheet

99.00

Related Targets	CFTR CRM1 AChR Calcium Channel Sodium Channel Potassium Channel GABA Receptor TRP Channel ATPase GluR
Other CD markers Products	CD38 inhibitor 1 (compound 78c) Anti-CD83 SodiuM Metatungstate NQ301 LY-3475070 Relatlimab (anti-LAG-3) Apamistamab (Anti-PTPRC / CD45) Dalotuzumab (Anti-IGF1R / CD221) E-Cadherin Antibody [P11M9] Neihulizumab (Anti-PSGL1 / CD162)

Solubility

In vitro
Batch:

DMSO : 19 mg/mL (49.42 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : Insoluble

Ethanol : Insoluble

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
Mass value Mass unit	Concentration value Concentration unit	Volume value Volume unit	Molecular weight (g/mol)

Dilution Calculator Molecular Weight Calculator

In vivo batch selection In vivo Batch:
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal: μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO

% Tween 80

% ddH₂O

% DMSO

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight	384.43	Formula	C₁₉H₂₄N₆O₃	Storage (From the date of receipt)	3 years -20°C powder
CAS No.	2597933-17-8	--		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent

Mechanism of Action

Targets/IC₅₀/Ki	CD38 0.01μM
References	[1] https://patents.google.com/patent/WO2021021986A1

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Handling Instructions

Tel: +1-832-582-8158 Ext:3

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