Cynarin

Catalog No.S3301 Synonyms: Cynarine

For research use only.

Cynarin (Cynarine) is an artichoke phytochemical that possesses a variety of pharmacological features including free-radical scavenging, antioxidant, antihistamic and antiviral activities. Cynarin blocks the interaction between the CD28 of T-cell receptor and CD80 of antigen presenting cells. Cynarin triggers Nrf2 nuclear translocation, restores the balance of glutathione (GSH) and reactive oxygen species (ROS), and inhibits mitochondrial depolarization.

Cynarin Chemical Structure

CAS No. 30964-13-7

Purity & Quality Control

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Biological Activity

Description Cynarin (Cynarine) is an artichoke phytochemical that possesses a variety of pharmacological features including free-radical scavenging, antioxidant, antihistamic and antiviral activities. Cynarin blocks the interaction between the CD28 of T-cell receptor and CD80 of antigen presenting cells. Cynarin triggers Nrf2 nuclear translocation, restores the balance of glutathione (GSH) and reactive oxygen species (ROS), and inhibits mitochondrial depolarization.
Targets
CD28 - CD80 interaction [1] Nrf2 [2] GSH [2] ROS [2]

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 516.45
Formula

C25H24O12

CAS No. 30964-13-7
Storage 3 years -20°C powder
2 years -80°C in solvent

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