Home Metabolism Acetyl-CoA carboxylase chemical Oxalacetic acid For research use only.

Oxalacetic acid

Synonyms: Oxaloacetic acid, 2-Oxosuccinic acid, Ketosuccinic acid

Oxalacetic acid (Oxaloacetic acid, 2-Oxosuccinic acid, Ketosuccinic acid) is an intermediate of the citric acid cycle, where it reacts with acetyl-CoA to form citrate, catalysed by citrate synthase. It is also involved in gluconeogenesis, urea cycle, glyoxylate cycle, amino acid synthesis, and fatty acid synthesis. Oxaloacetate is also a potent inhibitor of Complex II.

Oxalacetic acid Chemical Structure

Oxalacetic acid Chemical Structure

CAS: 328-42-7

Purity & Quality Control

Batch: S611201 Water] 100 mg/mL] false] DMSO] 26 mg/mL] false] ] ] false Purity: 99.96%
99.96

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Biological Activity

Description Oxalacetic acid (Oxaloacetic acid, 2-Oxosuccinic acid, Ketosuccinic acid) is an intermediate of the citric acid cycle, where it reacts with acetyl-CoA to form citrate, catalysed by citrate synthase. It is also involved in gluconeogenesis, urea cycle, glyoxylate cycle, amino acid synthesis, and fatty acid synthesis. Oxaloacetate is also a potent inhibitor of Complex II.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06001034 Completed
Fibromyalgia
José Carlos Rodríguez Bautista|Universidad Pablo de Olavide|Hospital Universitario de Valme|Andaluz Health Service
 September 15 2022 Not Applicable

Chemical Information & Solubility

Molecular Weight 132.07 Formula

C4H4O5
CAS No. 328-42-7 SDF --
Smiles C(C(=O)C(=O)O)C(=O)O
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

Water : 100 mg/mL

DMSO : 26 mg/mL ( (196.86 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


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In vivo
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Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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