Home Metabolism Acetyl-CoA carboxylase chemical Oxalacetic acid

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Oxalacetic acid Acetyl-CoA carboxylase chemical

Cat.No.S6112

Oxalacetic acid (Oxaloacetic acid, 2-Oxosuccinic acid, Ketosuccinic acid) is an intermediate of the citric acid cycle, where it reacts with acetyl-CoA to form citrate, catalysed by citrate synthase. It is also involved in gluconeogenesis, urea cycle, glyoxylate cycle, amino acid synthesis, and fatty acid synthesis. Oxaloacetate is also a potent inhibitor of Complex II.
Oxalacetic acid Acetyl-CoA carboxylase chemical Chemical Structure

Chemical Structure

Molecular Weight: 132.07

Jump to Mechanism of Action Solubility Chemical Information, Storage & Stability

Quality Control

Batch: S611201 Water]100 mg/mL]false]DMSO]26 mg/mL]false]]]false Purity: 99.96%
99.96

Chemical Information, Storage & Stability

Molecular Weight 132.07 Formula

C4H4O5

 Storage (From the date of receipt) 3 years -20°C powder
CAS No. 328-42-7 -- Storage of Stock Solutions

Synonyms Oxaloacetic acid, 2-Oxosuccinic acid, Ketosuccinic acid Smiles C(C(=O)C(=O)O)C(=O)O

Solubility

In vitro
Batch:

Water : 100 mg/mL

DMSO : 26 mg/mL (196.86 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo
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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06001034 Completed
Fibromyalgia
José Carlos Rodríguez Bautista|Universidad Pablo de Olavide|Hospital Universitario de Valme|Andaluz Health Service
 September 15 2022 Not Applicable

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