NU7441 (KU-57788)

For research use only.

Catalog No.S2638

103 publications

NU7441 (KU-57788) Chemical Structure

Molecular Weight(MW): 413.49

NU7441 (KU-57788) is a highly potent and selective DNA-PK inhibitor with IC50 of 14 nM and also inhibits PI3K with IC50 of 5 μM in cell-free assays. It reduces the frequency of NHEJ while increasing the rate of HDR following Cas9-mediated DNA cleavage.

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Selleck's NU7441 (KU-57788) has been cited by 103 publications

Purity & Quality Control

Choose Selective DNA-PK Inhibitors

Biological Activity

Description NU7441 (KU-57788) is a highly potent and selective DNA-PK inhibitor with IC50 of 14 nM and also inhibits PI3K with IC50 of 5 μM in cell-free assays. It reduces the frequency of NHEJ while increasing the rate of HDR following Cas9-mediated DNA cleavage.
Targets
DNA-PK [1]
(Cell-free assay)
14 nM
In vitro

NU7441 increases the persistence of γH2AX foci after ionizing radiation–induced or etoposide-induced DNA damage. NU7441 (0.5 μM or 1 μM) appreciably increases G2-M accumulation induced by ionizing radiation, etoposide, and doxorubicin in both SW620 and LoVo cells. [2] NU7441 causes persistence of doxorubicin- and ionising radiation-induced DNA double-strand break and also slightly decreases homologous recombination activity DNA-PK-proficient M059-Fus-1 and DNA-PK-deficient M059 J human tumour cells. [3] NU7441 inhibits UV-induced RPA p34 hyperphosphorylation in a dose-dependent manner both in cells lacking and cells expressing polymerase η. [4] NU7441 increases levels of fludarabine-induced γH2AX foci and correspondingly decreased fludarabine-induced cell death in chronic lymphocytic leukemia cells. [5] NU7441 also inhibits mitoxantrone-induced DNA-PKcs autophosphorylation and repair in chronic lymphocytic leukemia cells. [6] It reduces the frequency of NHEJ while increasing the rate of HDR following Cas9-mediated DNA cleavage[7].

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
NCI-H1770 NIrMZpVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGDibFJKSzVyPUCuNFIyPDNizszN MYHTRW5ITVJ?
A172 NYC2UHA4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUHJR|UxRTBwMUWzNVYh|ryP MYTTRW5ITVJ?
NCI-H526 MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4LOTGlEPTB;MD6yPFQxPyEQvF2= MWPTRW5ITVJ?
HDLM-2 M2fEUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M13zfmlEPTB;MD6zNlM1PSEQvF2= NUfqNZlxW0GQR1XS
HuO-3N1 NFHoZZRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlrGTWM2OD1yLkS2OlM3KM7:TR?= MkW1V2FPT0WU
NCI-SNU-1 MmrSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoG3TWM2OD1yLk[wPVk1KM7:TR?= M3vPcnNCVkeHUh?=
SK-N-AS MkjMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2\SZ2lEPTB;MD62NlIyPiEQvF2= MYTTRW5ITVJ?
LoVo MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkDQTWM2OD1yLki2O|Q6KM7:TR?= MlrPV2FPT0WU
LAMA-84 M3Hud2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{fwfGlEPTB;MD65PFg{OyEQvF2= NXWzTll1W0GQR1XS
CTB-1 M4jpZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4m3[2lEPTB;MT6xNVU1PiEQvF2= NHr0V3dUSU6JRWK=
KP-N-YS M2jocWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4fLWmlEPTB;MT6xOFI{OSEQvF2= MoDxV2FPT0WU
HH NH7GXHZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnzvTWM2OD1zLkG4NFk{KM7:TR?= MYfTRW5ITVJ?
CHL-1 NEXqZnhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4[4cmlEPTB;MT6yNVM3QCEQvF2= Mkn5V2FPT0WU
NB7 M{XWe2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIraXHRKSzVyPUGuNlQ4PDVizszN NEnid3VUSU6JRWK=
HL-60 MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MU\JR|UxRTFwM{ixPUDPxE1? NFXHOmhUSU6JRWK=
639-V NGrmdpRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEnNOmxKSzVyPUGuOFQyOjhizszN MlHDV2FPT0WU
NCI-H1793 NFHaRXlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1TaXmlEPTB;MT60OVg1KM7:TR?= MmqyV2FPT0WU
NEC8 M2i0eGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1\ObmlEPTB;MT61OVM2KM7:TR?= MUjTRW5ITVJ?
PA-1 M2rRdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVzJR|UxRTFwNUiyPVQh|ryP MorNV2FPT0WU
D-423MG MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn;tTWM2OD1zLk[5N|YyKM7:TR?= NELQS5BUSU6JRWK=
NCI-H292 M3nUbmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4rZNmlEPTB;MT63OFAyOyEQvF2= MmPOV2FPT0WU
SK-MEL-1 MlHCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4L3bmlEPTB;MT63PVQ4QSEQvF2= MnnpV2FPT0WU
LB2241-RCC MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4nUSmlEPTB;Mj6xOFE1PiEQvF2= MmLVV2FPT0WU
SK-MEL-3 NYrQeJVQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVrJR|UxRTJwMU[0PUDPxE1? NUnKXlMzW0GQR1XS
MHH-PREB-1 NInJN|BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnvjTWM2OD1{LkG2OlA6KM7:TR?= NG\HNFRUSU6JRWK=
BFTC-905 Mlm3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHXafnVKSzVyPUKuNVY3QDdizszN MYXTRW5ITVJ?
Ramos-2G6-4C10 MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkPsTWM2OD1{LkG5PVA6KM7:TR?= NHu1[5dUSU6JRWK=
G-361 M33qUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWPYOHBKUUN3ME2yMlIyPjhizszN MXLTRW5ITVJ?
MOLT-4 NXW0U5RwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVryNW1CUUN3ME2yMlIyQDh6IN88US=> NWDFbVlsW0GQR1XS
DEL NGG4fGhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHfVfYVKSzVyPUKuN|U2PjRizszN NI[3WJJUSU6JRWK=
MV-4-11 NWDKWGNIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWjJR|UxRTJwM{ezPUDPxE1? MoW2V2FPT0WU
SK-NEP-1 M1ntV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXzsU3k1UUN3ME2yMlM5Pzh|IN88US=> M1TKeHNCVkeHUh?=
RS4-11 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnXjTWM2OD1{LkW2NFI{KM7:TR?= NVjpfnptW0GQR1XS
HuH-7 M3PNNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWD4Z5BzUUN3ME2yMlU3PzB{IN88US=> NEXiT5BUSU6JRWK=
A101D NFy5ZZdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2HRTGlEPTB;Mj62NVM{QCEQvF2= MnHGV2FPT0WU
KG-1 NVPVTGt3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEfDOWZKSzVyPUKuOlc6OjRizszN NYHYbm9{W0GQR1XS
KALS-1 NYCx[GtLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmH5TWM2OD1{Lk[5OlM{KM7:TR?= NWHLfotjW0GQR1XS
VMRC-RCZ NIHiUXNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHn4OJZKSzVyPUKuO|c{OjhizszN MY\TRW5ITVJ?
SK-UT-1 MnHES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{LFSGlEPTB;Mz6xOVMyKM7:TR?= MnG1V2FPT0WU
SW962 NVKybZFuT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml:wTWM2OD1|LkKwN|UzKM7:TR?= MlnlV2FPT0WU
DBTRG-05MG M2m5fWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3\E[2lEPTB;Mz6yPFA5PSEQvF2= M3O3SXNCVkeHUh?=
PANC-08-13 MlP6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmH2TWM2OD1|LkSxNlc5KM7:TR?= NHjZPJFUSU6JRWK=
QIMR-WIL MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2\ZXGlEPTB;Mz60NVM1OSEQvF2= NFPSNXBUSU6JRWK=
SK-MEL-30 M1PiN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHPvXllKSzVyPUOuOFI2QThizszN MU\TRW5ITVJ?
697 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlmwTWM2OD1|LkS0PVk{KM7:TR?= M2njSHNCVkeHUh?=
NY MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXrIe4tKUUN3ME2zMlQ2ODJ{IN88US=> MYXTRW5ITVJ?
ES7 M2TObWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1WweGlEPTB;Mz60OlczQSEQvF2= MlWzV2FPT0WU
JVM-3 NVPRVlRWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2jMZmlEPTB;Mz60PFA4PyEQvF2= MmPjV2FPT0WU
U031 NYHnelZYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mlu0TWM2OD1|LkW5N|Y5KM7:TR?= NXrzTnVOW0GQR1XS
BHT-101 MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVPtO3I{UUN3ME2zMlU6QTh3IN88US=> NXrUN|l5W0GQR1XS
8305C NYS5WGJ3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NILPV2dKSzVyPUOuOlE4OzZizszN NFXM[ZdUSU6JRWK=
MG-63 NHHV[2FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVnJR|UxRTNwNkK2O|Yh|ryP M2TwTHNCVkeHUh?=
NOS-1 NVr5SZI5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2\0N2lEPTB;Mz62OVMyOiEQvF2= M3LnTXNCVkeHUh?=
YH-13 MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX7JR|UxRTNwOEexPFkh|ryP NHfpbItUSU6JRWK=
LXF-289 NHKzb4NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmfkTWM2OD1|LkmxNFQyKM7:TR?= NUTyVmRNW0GQR1XS
GOTO NEHUXpNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NW\EblJvUUN3ME2zMlkyPDlizszN MWHTRW5ITVJ?
EKVX MlTmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYTaSnp1UUN3ME20MlIzPTJ2IN88US=> MX7TRW5ITVJ?
CAL-51 MnX0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3\icmlEPTB;ND6yOFg2PCEQvF2= MXLTRW5ITVJ?
AN3-CA MnjQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIrne3hKSzVyPUSuNlU5OTNizszN NXT5XGxRW0GQR1XS
IA-LM NHTDWWJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXnCR5lNUUN3ME20MlI4QTN3IN88US=> M2X2WXNCVkeHUh?=
KU-19-19 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUDWSZNVUUN3ME20MlMzQTJzIN88US=> NIjHU|RUSU6JRWK=
A704 M1zVS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MULJR|UxRTRwNEC4PFgh|ryP MYLTRW5ITVJ?
RH-18 Mlz0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYjpOFhqUUN3ME20MlQ1QTV|IN88US=> Mn7EV2FPT0WU
IST-MEL1 MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYfDdINJUUN3ME20MlU5OjZ|IN88US=> NXr2TFZRW0GQR1XS
LU-134-A NF;xZZNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXy5ToFqUUN3ME20MlU6Pjh3IN88US=> MkPyV2FPT0WU
SF126 NFjxboJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXrUNmJIUUN3ME20MlYxPzF3IN88US=> MVXTRW5ITVJ?
EFO-27 M{\UXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MonoTWM2OD12Lk[2OVI2KM7:TR?= NVLuWnVPW0GQR1XS
SN12C MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnvuTWM2OD12LkexPFk5KM7:TR?= M{DnZnNCVkeHUh?=
L-363 NV3YNnhNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3nzVmlEPTB;ND63O|EyPiEQvF2= NIra[49USU6JRWK=
MEL-HO MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1qxd2lEPTB;ND63O|k5QSEQvF2= MVTTRW5ITVJ?
TYK-nu M1\5NGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHr5Ro1KSzVyPUSuPFAyOjhizszN NVTz[mUyW0GQR1XS
MDA-MB-415 M{fPemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4HITGlEPTB;NT6wNFMyPCEQvF2= MVTTRW5ITVJ?
HCC70 M3zHbWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkjlTWM2OD13LkCzPVM6KM7:TR?= MlvuV2FPT0WU
IGROV-1 M3nXXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnL5TWM2OD13LkK1NlkzKM7:TR?= M2S3U3NCVkeHUh?=
NCI-H1355 NUfNd|Y{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2\xe2lEPTB;NT6yPVYh|ryP MU\TRW5ITVJ?
23132-87 NIXTe2FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWPEdmdIUUN3ME21MlMzODJ2IN88US=> M{SzXHNCVkeHUh?=
NB69 NXzkNVNtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoDXTWM2OD13LkOyOFIh|ryP M4Tke3NCVkeHUh?=
HSC-2 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2fsT2lEPTB;NT60NVc4OyEQvF2= M3LER3NCVkeHUh?=
KYSE-410 MmL3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX;KVpNQUUN3ME21MlQ4PjN4IN88US=> MoDEV2FPT0WU
GCIY NVe4NXUyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEj2XHdKSzVyPUWuOVE{PzhizszN MlzoV2FPT0WU
A427 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYrJR|UxRTVwNUO2OlEh|ryP MWLTRW5ITVJ?
ChaGo-K-1 M2SyOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXTJR|UxRTVwNU[1PVkh|ryP Mnm2V2FPT0WU
PFSK-1 Ml64S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml7nTWM2OD13Lk[yNVk1KM7:TR?= M4TkbXNCVkeHUh?=
MLMA NILTbldIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NF\mVnBKSzVyPUWuPFM3ODZizszN NWnsZ2JPW0GQR1XS
RVH-421 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF\LPYFKSzVyPU[uNFc{OzhizszN MVjTRW5ITVJ?
LB1047-RCC MmTtS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX;JR|UxRTZwMUe1NlIh|ryP NYfiU2dTW0GQR1XS
MHH-NB-11 MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml7LTWM2OD14LkOyO|IyKM7:TR?= NYXNZlJ7W0GQR1XS
J-RT3-T3-5 MmriS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4HsTGlEPTB;Nj62N|I6OSEQvF2= NEHIWHZUSU6JRWK=
UM-UC-3 MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXHrboxqUUN3ME22MlY1OzN2IN88US=> M1;zU3NCVkeHUh?=
IST-SL1 NWD2PJR{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUHJR|UxRTZwNkmzOlkh|ryP NYX2PVJSW0GQR1XS
NB14 NFm2VXVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Ml;YTWM2OD14Lke5O|YyKM7:TR?= MU\TRW5ITVJ?
NBsusSR MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHPjbGtKSzVyPU[uPFI2ODJizszN MXrTRW5ITVJ?
D-263MG Mnq1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn\wTWM2OD14LkmxNFY5KM7:TR?= MXTTRW5ITVJ?
NCI-H2347 Ml\MS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{n6R2lEPTB;Nj65N|IyOyEQvF2= MXHTRW5ITVJ?
ES8 Mm[2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{S2XGlEPTB;Nj65O|U5QCEQvF2= M4nab3NCVkeHUh?=
786-0 MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1nsUWlEPTB;Nz6wPVc5PiEQvF2= MWTTRW5ITVJ?
EPLC-272H MnTzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX3vTXV5UUN3ME23MlE3OjR4IN88US=> MVzTRW5ITVJ?
CAPAN-1 MmTIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX7JR|UxRTdwMkSzOVkh|ryP NVLEdXdsW0GQR1XS
NCI-H82 MnHNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4T0U2lEPTB;Nz6yOlY2QSEQvF2= Mn63V2FPT0WU
G-402 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEXZbopKSzVyPUeuN|AxPTFizszN MlrYV2FPT0WU
SW982 NEXvdYdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVTrR|FGUUN3ME23MlMxOjB|IN88US=> MV3TRW5ITVJ?
OVCAR-4 MnztS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmjsTWM2OD15LkOxN|I5KM7:TR?= MYDTRW5ITVJ?
KARPAS-299 MlTPS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoO1TWM2OD15LkOyOlIzKM7:TR?= MV3TRW5ITVJ?
MIA-PaCa-2 Ml\3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWnJR|UxRTdwM{[4NlMh|ryP NHLOemZUSU6JRWK=
AU565 MlT4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEflT2FKSzVyPUeuOVk5OzNizszN NFPSTGNUSU6JRWK=
GAMG NEXMT|BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1LiXWlEPTB;Nz62OFE{OSEQvF2= MlXxV2FPT0WU
HuO9 NFvre4pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3PDV2lEPTB;Nz63NVc1OyEQvF2= MnfTV2FPT0WU
ACN MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnHSTWM2OD15Lke0N|Mh|ryP MUXTRW5ITVJ?
RO82-W-1 NUXlOok1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUnJR|UxRTdwN{S1N|Mh|ryP NULCR|V3W0GQR1XS
NKM-1 M1frU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV;nRo4zUUN3ME23Mlc1QTV3IN88US=> NFr6[4ZUSU6JRWK=
CAL-12T MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVTseWdYUUN3ME23Mlk1OzV{IN88US=> NXzzUGl1W0GQR1XS
FADU M1Tne2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MULJR|UxRThwMEO2OVQh|ryP Mk\mV2FPT0WU
NCI-H28 Mn30S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3jTc2lEPTB;OD6xOlk3OiEQvF2= NI\QS3BUSU6JRWK=
LCLC-97TM1 NHzqfIxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NELWTpJKSzVyPUiuNlEyOjJizszN M3\VW3NCVkeHUh?=
CHP-134 NWHGbIJWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3\qfWlEPTB;OD6yOFE5PSEQvF2= M3;0THNCVkeHUh?=
HT-1080 NVeyZm9uT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M37QSmlEPTB;OD6yOVA6OyEQvF2= MXzTRW5ITVJ?
PC-3 MlLLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmL3TWM2OD16LkK3N|kzKM7:TR?= MVTTRW5ITVJ?
SNU-449 NHrCS3hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXHTdpFTUUN3ME24MlI4QTNizszN NUG1TGtVW0GQR1XS
VA-ES-BJ MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF\BdXNKSzVyPUiuN|Q3QDZizszN NFy5TIFUSU6JRWK=
HT NXv2R3hNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF\kNoRKSzVyPUiuN|Y1QSEQvF2= NEPJPFVUSU6JRWK=
HOS M{S3OGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFv0WJRKSzVyPUiuN|c2QDlizszN NXjqdZFWW0GQR1XS
KNS-62 M1jwTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWnxXVV3UUN3ME24MlM4PzZ{IN88US=> NF3LZYJUSU6JRWK=
OAW-42 MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXrFRo9qUUN3ME24Mlk2QTZ2IN88US=> NIr6U4FUSU6JRWK=
A549 M2XD[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1Lwb2lEPTB;OT6wPVYyOiEQvF2= M3\MenNCVkeHUh?=
CAKI-1 NYqwOmxVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MV\JR|UxRTlwMU[2NUDPxE1? NHXGeIVUSU6JRWK=
HCC1937 NIDpZmFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV\JR|UxRTlwNkm4OlUh|ryP NFPKcXdUSU6JRWK=
GI-ME-N M{Tydmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIe0fVhKSzVyPUmuO|AyOzdizszN M3n1[HNCVkeHUh?=
DU-4475 NIG3fW9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVnFc49mUUN3ME25Mlk3QTN7IN88US=> M{LZVXNCVkeHUh?=
EM-2 M{DUfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUPJR|UxRTFyLkK0NlYh|ryP MnHRV2FPT0WU
NCI-H1755 Ml3qS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGHncXpKSzVyPUGwMlI1OjhizszN MYfTRW5ITVJ?
NCI-H1437 MmLXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUfJXG1UUUN3ME2xNE42PzJ3IN88US=> NFrXN|lUSU6JRWK=
VM-CUB-1 MorRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF3RUJVKSzVyPUGwMlYyPjRizszN MX3TRW5ITVJ?
A2058 NEfBUolIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnfBTWM2OD1zMD62OFA1KM7:TR?= NVHyXHBpW0GQR1XS
BPH-1 M3SyXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4DFZ2lEPTB;MUCuO|E1PSEQvF2= NXrFdI41W0GQR1XS
NB5 NWnse3NHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4Lo[WlEPTB;MUCuO|U2QSEQvF2= NFHYNotUSU6JRWK=
G-401 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NImwfXdKSzVyPUGwMlc3OjZizszN NW\JSZhTW0GQR1XS
CAL-72 NHnGboNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHrwVYRKSzVyPUGwMlgxQTRizszN NX\PNIdZW0GQR1XS
SK-MEL-28 NH62VZJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXzvZY02UUN3ME2xNE45OjB{IN88US=> M{jvT3NCVkeHUh?=
C32 NEfXZ|hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUHJR|UxRTFyLkizOFch|ryP Mn7IV2FPT0WU
NCI-H1155 M{PBNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWXJR|UxRTFyLkizO|Yh|ryP NETx[pZUSU6JRWK=
BB49-HNC NFj6XWdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnvyTWM2OD1zMD64OVg3KM7:TR?= NV21b4oyW0GQR1XS
GMS-10 NET5bJJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1jvVmlEPTB;MUCuPFk4OSEQvF2= NUfRN|U{W0GQR1XS
K5 M1fUT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFLFWFhKSzVyPUGwMlkxPzFizszN MVTTRW5ITVJ?
OS-RC-2 NH3VPFdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4jvfWlEPTB;MUGuNFU2QSEQvF2= NFHOdY1USU6JRWK=
HTC-C3 M1qyWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2T6WmlEPTB;MUGuNFcyPCEQvF2= NHfWZpFUSU6JRWK=
LB996-RCC M2XvOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUThbm1FUUN3ME2xNU4xPzJ|IN88US=> M{LUXnNCVkeHUh?=
NCI-H1563 M{XXVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUnlOFdHUUN3ME2xNU4yODFzIN88US=> M1PkXHNCVkeHUh?=
CAL-54 NV3PVGdQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUO5fXExUUN3ME2xNU41QDFzIN88US=> Mn\hV2FPT0WU
WM-115 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3HDOWlEPTB;MUGuOlgzPCEQvF2= MoHSV2FPT0WU
COLO-684 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MY\JR|UxRTFzLkeyOlch|ryP NH:5T|VUSU6JRWK=
HOP-62 M3n2Tmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIL2WHBKSzVyPUGxMlc2ODhizszN NYXWdHZ7W0GQR1XS
NCI-H650 M4X4dmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFjEWGpKSzVyPUGxMlg6PjFizszN NHPrclVUSU6JRWK=
TE-11 M4jMfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGWwbW1KSzVyPUGxMlk{OTVizszN MX;TRW5ITVJ?
COLO-679 NE\TXnNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWPvT5BRUUN3ME2xNU46PDZizszN MojsV2FPT0WU
FTC-133 NWK4cmZPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlrHTWM2OD1zMj6wNFc3KM7:TR?= MnTNV2FPT0WU
D-283MED MkPQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXK1WJBtUUN3ME2xNk4xPTZ7IN88US=> NGXrZ45USU6JRWK=
SK-PN-DW MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3HMTmlEPTB;MUKuNVkxOiEQvF2= NGDCZ41USU6JRWK=
BALL-1 MoLBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkHwTWM2OD1zMj6yOlYzKM7:TR?= MV7TRW5ITVJ?
GT3TKB M{TtcWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVXJR|UxRTF{LkOwO|Qh|ryP MXnTRW5ITVJ?
HOP-92 NFyxbGRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVXJR|UxRTF{LkWyN|Mh|ryP M{Dm[HNCVkeHUh?=
M14 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX\JR|UxRTF|LkCzN|Uh|ryP MoHnV2FPT0WU
SKG-IIIa NIXkdGxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV\FVoZPUUN3ME2xN{4xPTV2IN88US=> NX\Jbmw3W0GQR1XS
Becker NX\wWHp3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV74OWViUUN3ME2xN{4xPThizszN MV\TRW5ITVJ?
ES5 MkfoS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHq3cVVKSzVyPUGzMlE{PTZizszN M4rtNnNCVkeHUh?=
NCI-H2030 MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWfVenlIUUN3ME2xN{4zODZ{IN88US=> M4\6eXNCVkeHUh?=
SNU-423 NHjy[W9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3fySWlEPTB;MUOuN|gyKM7:TR?= NI[5ZohUSU6JRWK=
CP50-MEL-B MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1zSemlEPTB;MUOuOlI{OiEQvF2= MWLTRW5ITVJ?
NCI-H1092 NIfZUZlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH\6enNKSzVyPUGzMlc1PzVizszN MknlV2FPT0WU
8-MG-BA Mnf6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn3TTWM2OD1zMz63OVE{KM7:TR?= MVnTRW5ITVJ?
CAL-27 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MY\JR|UxRTF2LkC3Nlch|ryP M136SHNCVkeHUh?=
AGS MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYXnWIdUUUN3ME2xOE4yOzF7IN88US=> NHTmdnNUSU6JRWK=
MZ2-MEL NF;VWVNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmnoTWM2OD1zND6xOFg5KM7:TR?= M3XDR3NCVkeHUh?=
BFTC-909 NFLBWYhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWfJR|UxRTF2LkWwOVUh|ryP MnfFV2FPT0WU
D-566MG NGfZeIRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnHHTWM2OD1zND63O|A3KM7:TR?= M4fpOnNCVkeHUh?=
MZ7-mel NGf4[4ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NITvTW5KSzVyPUG1MlExPjdizszN NH\FO3pUSU6JRWK=
TE-5 MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn7sTWM2OD1zNT6yN|M{KM7:TR?= MV3TRW5ITVJ?
647-V MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYrJR|UxRTF3LkK3NFUh|ryP M172eHNCVkeHUh?=
DMS-114 M2TP[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4nKdGlEPTB;MUWuN|I6OSEQvF2= MkO3V2FPT0WU
ME-180 NWK0SJY1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVKwT4ZyUUN3ME2xOU41Pzh|IN88US=> MXfTRW5ITVJ?
MS-1 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmrsTWM2OD1zNT61OlI{KM7:TR?= NX\0foZNW0GQR1XS
NUGC-3 M1:0V2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4nWdGlEPTB;MUWuOlI1PSEQvF2= NV7aZZpWW0GQR1XS
GB-1 M3\scmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NX\5RXhpUUN3ME2xOU43PDN5IN88US=> MnmyV2FPT0WU
LOXIMVI NYmyfXVQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHjnSoNKSzVyPUG1Mlg6OTlizszN NGmwbZpUSU6JRWK=
NCI-H1304 NGHWXGlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWfzRnplUUN3ME2xOU45QTJ6IN88US=> NGn2SI1USU6JRWK=
KURAMOCHI NFTaVnBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUfJR|UxRTF3Lkm3NUDPxE1? NH;xPHdUSU6JRWK=
SW1783 NYPtUFUyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF;COoZKSzVyPUG2MlA6QTNizszN MXfTRW5ITVJ?
EGI-1 NIDYOZhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXTJR|UxRTF4LkWzOlUh|ryP MoPrV2FPT0WU
KGN NUjtcGtRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mm\CTWM2OD1zNj61OVg3KM7:TR?= M4TSTHNCVkeHUh?=
PANC-03-27 M3\nUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHfzeIJKSzVyPUG2Mlc3PjJizszN NIrh[lBUSU6JRWK=
RH-1 M3PYW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYfsbIZ7UUN3ME2xOk45OjVizszN Mo\wV2FPT0WU
HT-1376 M4qydGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVTJR|UxRTF4Lki0OFYh|ryP NInrdJdUSU6JRWK=
ZR-75-30 NW[zRmkxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIrVc49KSzVyPUG2Mlk{PjFizszN M3ixXHNCVkeHUh?=
TI-73 M4jQSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYrJR|UxRTF4Lkm0NFgh|ryP NXnUO2Q4W0GQR1XS
TK10 MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn30TWM2OD1zNz6wNFc6KM7:TR?= NXPWWItMW0GQR1XS
SW684 M1G2XGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3LTSWlEPTB;MUeuNFE2PCEQvF2= NUXGTZhOW0GQR1XS
RPMI-8866 NHLnWWpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIPadYxKSzVyPUG3MlA3QTlizszN NGHFWWVUSU6JRWK=
LNCaP-Clone-FGC MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVjJR|UxRTF5LkWyNFEh|ryP MmnVV2FPT0WU
NCI-H2291 NHu3WZpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEHwNo5KSzVyPUG4MlQ{PDVizszN MkLSV2FPT0WU
T47D M2Pwfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWnJR|UxRTF6LkS4PEDPxE1? NX76Z491W0GQR1XS
A204 NIHBSIhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYPZeHFuUUN3ME2xPE42PDV{IN88US=> NIDZenNUSU6JRWK=
HT-144 NWDj[2E2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUH1RWVvUUN3ME2xPE44PDJ5IN88US=> NIfEdWxUSU6JRWK=
MDA-MB-361 NHvUV5hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVfsT5lDUUN3ME2xPU4xPzF2IN88US=> M2r0PHNCVkeHUh?=
HCC1806 MkT6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFHncVlKSzVyPUG5MlE2QTFizszN M{HxfXNCVkeHUh?=
NCI-H596 NGq5PWdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnPuTWM2OD1zOT62N|kyKM7:TR?= M3zEWnNCVkeHUh?=
K-562 Ml3DS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml3wTWM2OD1zOT64PVI3KM7:TR?= M{f4WnNCVkeHUh?=
D-336MG MkXwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4n6RmlEPTB;MUmuPVMzOiEQvF2= NUTGenZ6W0GQR1XS
SK-MEL-2 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGnUNXJKSzVyPUKwMlE2PTlizszN MlfzV2FPT0WU
HEC-1 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2ThbmlEPTB;MkCuOFk4QCEQvF2= M{n3WHNCVkeHUh?=
EW-13 NH73Z3VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH;K[nVKSzVyPUKwMlU1PDNizszN M2DwbHNCVkeHUh?=
Hs-578-T MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3f4PGlEPTB;MkCuOVU5OyEQvF2= MYLTRW5ITVJ?
SJSA-1 NIPyRXhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1PmWWlEPTB;MkCuOVY5QCEQvF2= MkK3V2FPT0WU
RCC10RGB M{SxcWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYDCN45sUUN3ME2yNE43PzF7IN88US=> M1O0VXNCVkeHUh?=
LAN-6 MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MULJR|UxRTJzLkCzPVYh|ryP MW\TRW5ITVJ?
NCI-H1048 NXTXb3A5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXjTSnQ{UUN3ME2yNU4zOjV6IN88US=> MYLTRW5ITVJ?
CW-2 Mn;WS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFjKVlBKSzVyPUKxMlI4ODVizszN NV7iV5E2W0GQR1XS
HCC2157 M1PUOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWXJR|UxRTJzLkO2JO69VQ>? NGniSZRUSU6JRWK=
EW-22 NGXwZnpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUC2Z3E4UUN3ME2yNU4{PzZizszN M1Ln[nNCVkeHUh?=
A253 MkPDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXfJR|UxRTJzLkS0PFEh|ryP M1PuVnNCVkeHUh?=
BE-13 NH;LU4ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{P2dmlEPTB;MkGuOlEyOyEQvF2= M13aV3NCVkeHUh?=
KINGS-1 NHrUZldIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MW\JR|UxRTJzLk[zNVYh|ryP MmjJV2FPT0WU
ETK-1 M{W2fGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmLQTWM2OD1{MT64NVUzKM7:TR?= M2myZnNCVkeHUh?=
NCI-H2452 M1ez[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXj0TokxUUN3ME2yNU45PjR5IN88US=> NWWwO|hsW0GQR1XS
HPAF-II MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXTLSYF[UUN3ME2yNU45QTJ|IN88US=> MlL1V2FPT0WU
D-542MG MljJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXvJR|UxRTJzLkmwOlkh|ryP NHGyUIdUSU6JRWK=
NCI-H630 M3;lcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVTJR|UxRTJ{LkCyPVYh|ryP NWToVVFVW0GQR1XS
TGBC11TKB MnT4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlX2TWM2OD1{Mj6wOFkh|ryP NGPUbZJUSU6JRWK=
BCPAP MkXsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX7RPIZ2UUN3ME2yNk43OTFizszN MmnXV2FPT0WU
HLE MoHjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEPoRnVKSzVyPUKyMlY6PyEQvF2= M2\WdHNCVkeHUh?=
NCI-H727 NUHkPXdHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NI\kNlBKSzVyPUKyMlc{PSEQvF2= NXLUNI1jW0GQR1XS
RD M1Xsbmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVHJR|UxRTJ{Lke1NVgh|ryP MnvhV2FPT0WU
NCI-H522 M{nkO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVfpclZKUUN3ME2yNk45PDNzIN88US=> MVLTRW5ITVJ?
CGTH-W-1 MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUjXXHJ{UUN3ME2yN{4xPjRzIN88US=> MYnTRW5ITVJ?
SK-LU-1 NF7PVYZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlXBTWM2OD1{Mz60Olg{KM7:TR?= NYPHWFhlW0GQR1XS
BB65-RCC NGrqbXpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUHGToJ3UUN3ME2yN{44QDZ|IN88US=> NVfre4dmW0GQR1XS
HSC-3 Mmi3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHW5SWRKSzVyPUKzMlg2OjdizszN MVnTRW5ITVJ?
SK-MES-1 MoHUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUPJR|UxRTJ2LkCxOlEh|ryP NWD4[FBFW0GQR1XS
DB NGrSSHRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkXYTWM2OD1{ND6xNFI5KM7:TR?= M1TP[HNCVkeHUh?=
HO-1-N-1 Mof2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXLLN|RlUUN3ME2yOE4{ODl|IN88US=> MWjTRW5ITVJ?
MKN1 Mn3FS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUTJR|UxRTJ2Lk[4JO69VQ>? NFThWXpUSU6JRWK=
MN-60 NWTRZ4NbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYfJR|UxRTJ2Lki1NVkh|ryP Mmi1V2FPT0WU
8505C M4DDe2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYPHPFh1UUN3ME2yOU4yQDR3IN88US=> MX7TRW5ITVJ?
COLO-320-HSR MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml;XTWM2OD1{NT6yNlA5KM7:TR?= NH\ZN3BUSU6JRWK=
BB30-HNC MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXrpSldWUUN3ME2yOU4zPDh|IN88US=> M2Dj[3NCVkeHUh?=
KM12 MkfhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUfJR|UxRTJ3LkW4NFch|ryP MmLCV2FPT0WU
NB13 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1joVGlEPTB;MkWuOVg6QCEQvF2= M13R[3NCVkeHUh?=
HCC2998 MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUDJR|UxRTJ4LkCyPFMh|ryP MlnVV2FPT0WU
U-118-MG MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3fmdGlEPTB;Mk[uNFgxQCEQvF2= MYDTRW5ITVJ?
NB10 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlftTWM2OD1{Nj6yN|Qh|ryP NG\UdVJUSU6JRWK=
SK-LMS-1 M3nkNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml[xTWM2OD1{Nz6wO|A1KM7:TR?= NV:4V2l4W0GQR1XS
SW1573 NWfYPW54T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHKxRXhKSzVyPUK3MlEyKM7:TR?= MYrTRW5ITVJ?
LB373-MEL-D NH\QXZhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYn2VmQ2UUN3ME2yO{4yOjl2IN88US=> NXy0dI05W0GQR1XS
DK-MG NFi2WWNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4Cz[WlEPTB;MkeuNVgyPyEQvF2= MVTTRW5ITVJ?
RMG-I M2DOSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVvJR|UxRTJ5LkKwNlkh|ryP M3XVfHNCVkeHUh?=
SW1088 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXzJR|UxRTJ5LkWwOFIh|ryP MYjTRW5ITVJ?
SK-OV-3 Ml;0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGDrcpZKSzVyPUK3Mlc2QTNizszN NX:0[JNqW0GQR1XS
KP-N-YN NWj4[ZBjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWn4PGFOUUN3ME2yO{45ODR|IN88US=> MkDZV2FPT0WU
RPMI-7951 MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX;MWJcxUUN3ME2yPE4zPDV4IN88US=> MmLEV2FPT0WU
CaR-1 NX\wc3JZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGnmc2dKSzVyPUK4MlU2QDJizszN M3HDfHNCVkeHUh?=
MKN7 NILPT2ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHmxTmdKSzVyPUK4MlU6PjRizszN NVrId2VPW0GQR1XS
CHP-212 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXPnbYJrUUN3ME2yPE44PDBzIN88US=> M3z3NHNCVkeHUh?=
KYSE-450 NHT2WG5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIWzUW9KSzVyPUK4MlgxQTFizszN M4PnXXNCVkeHUh?=
RXF393 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NH:5VXBKSzVyPUK5MlI6ODZizszN NHHpeIRUSU6JRWK=
P30-OHK MoO1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUX5fG56UUN3ME2yPU4{ODR6IN88US=> MVXTRW5ITVJ?
Ca9-22 NUi4b4VrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYTJR|UxRTJ7LkSyPVkh|ryP M4DkXnNCVkeHUh?=
RT-112 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkDBTWM2OD1{OT60OlEyKM7:TR?= MVzTRW5ITVJ?
ES1 NGrI[oxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Ml3DTWM2OD1{OT64OVQ1KM7:TR?= Mn\RV2FPT0WU
HCE-4 NVLiT3ROT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1LRfmlEPTB;MkmuPFc5PiEQvF2= M2LGd3NCVkeHUh?=
AM-38 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1nt[2lEPTB;M{CuNFYxPiEQvF2= MXTTRW5ITVJ?
AsPC-1 Mly4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkKwTWM2OD1|MD64NFU{KM7:TR?= NXjodpRHW0GQR1XS
TE-9 M1LXdmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUjxO3ltUUN3ME2zNE45PzN5IN88US=> NHPkfohUSU6JRWK=
HuP-T4 MlTsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV\JR|UxRTNyLkm2N|gh|ryP M4PaUnNCVkeHUh?=
LB2518-MEL M1PSXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmHQTWM2OD1|MT6wO|Q1KM7:TR?= MYDTRW5ITVJ?
NCI-H1703 MkXLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWLJR|UxRTNzLkC5NFUh|ryP M1vxd3NCVkeHUh?=
NCI-H2228 M1PENGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXjJR|UxRTNzLkS2OVEh|ryP MWDTRW5ITVJ?
SCC-4 M1T4S2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFXCdHhKSzVyPUOxMlkyQDFizszN MUfTRW5ITVJ?
KNS-81-FD NHjaXG5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{\LZ2lEPTB;M{KuNFEzQCEQvF2= MY\TRW5ITVJ?
NTERA-S-cl-D1 NFLqW49Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkHsTWM2OD1|Mj6wO|M6KM7:TR?= MoTpV2FPT0WU
Daoy NXzPfFhKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlnpTWM2OD1|Mj6wPFM5KM7:TR?= Mof6V2FPT0WU
ES4 MlzaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{TsSGlEPTB;M{KuN|kzOiEQvF2= NEfpZ45USU6JRWK=
MHH-ES-1 M2KzcWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVTJR|UxRTN{LkS4O|Ih|ryP M1y4XHNCVkeHUh?=
C-33-A NHLDd49Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWjISGplUUN3ME2zNk44PzJ6IN88US=> NYDucWo{W0GQR1XS
BHY M1fEcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUHJR|UxRTN{Lkm0PVUh|ryP NHHtRmJUSU6JRWK=
Detroit562 M{TwSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnLFTWM2OD1|Mz62OlU4KM7:TR?= NYq2OoRxW0GQR1XS
EW-1 MnP0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NW[3cZd7UUN3ME2zN{46OzJ{IN88US=> M3W4dHNCVkeHUh?=
NCI-H1395 NETlPFNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUfJR|UxRTN2LkC3PVkh|ryP NUS1S2VXW0GQR1XS
KM-H2 Mkn5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWDJR|UxRTN4LkS3OFMh|ryP MUnTRW5ITVJ?
NCI-H520 NXPKfnNnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoizTWM2OD1|Nj63OVQyKM7:TR?= MVfTRW5ITVJ?
D-392MG M3X1Omdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoHITWM2OD1|Nz6zN|Q1KM7:TR?= NUDYZpdyW0GQR1XS
NOMO-1 M1ewUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGPGZpZKSzVyPUO3MlgxQDlizszN NXXFZYNCW0GQR1XS
TE-6 NX7rdYdDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFfVUWhKSzVyPUO4MlEzPCEQvF2= NUTBc3h[W0GQR1XS
HT-3 NWS5TnpJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3rQeWlEPTB;M{iuOFQ{PiEQvF2= NXX2d5ZyW0GQR1XS
RPMI-8226 NFLuWHlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlvYTWM2OD1|OD65OVE6KM7:TR?= NWP5bmlFW0GQR1XS
U251 M3K4SGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M16xWGlEPTB;M{muNFEzPCEQvF2= NHqxTpdUSU6JRWK=
GCT NYP4eIVDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkfUTWM2OD1|OT6xPFUzKM7:TR?= MWnTRW5ITVJ?
A431 M4XPVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEDFTXVKSzVyPUO5MlE5QTRizszN MWPTRW5ITVJ?
TE-12 MofXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmLVTWM2OD1|OT6yOFQ5KM7:TR?= MmnOV2FPT0WU
HMV-II Mof3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVPJR|UxRTN7LkWwOFch|ryP NHLPXlRUSU6JRWK=
IST-MES1 MkXSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH\FdlNKSzVyPUSwMlE2ODJizszN NXW1eJhnW0GQR1XS
SW13 M1voWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXrtXnhyUUN3ME20NE42OTlizszN NFjUNW9USU6JRWK=
SF295 NHzuepBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4ewbWlEPTB;NECuPFA3PiEQvF2= NGXmTXJUSU6JRWK=
MDA-MB-157 MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoXZTWM2OD12MD65OFYzKM7:TR?= NXKyb2RoW0GQR1XS
TE-1 NYDiTINrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWKyclF[UUN3ME20NU45PzF2IN88US=> NVXaXHdRW0GQR1XS
HuCCT1 MmjXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mo\FTWM2OD12Mj61Nlg6KM7:TR?= NFPFVGVUSU6JRWK=
KYSE-510 NVXFfVhYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUj1SFZ[UUN3ME20N{4yPzV2IN88US=> NEjkcldUSU6JRWK=
NCI-H358 NU\E[GtDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1[2W2lEPTB;NESuNFMxPCEQvF2= M1\KVnNCVkeHUh?=
SW900 M17QSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVLJR|UxRTR2LkC3OVgh|ryP NEL2T3RUSU6JRWK=
CAS-1 Mn\4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX7JR|UxRTR2LkC5PVEh|ryP Mmm0V2FPT0WU
TE-8 NYnDemQ5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1fqWGlEPTB;NESuOVY2QCEQvF2= M{nTPXNCVkeHUh?=
P12-ICHIKAWA MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYrJR|UxRTR2Lk[xNVIh|ryP MmHzV2FPT0WU
YKG-1 NHzWPI5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVzJR|UxRTR2Lke4NUDPxE1? NXjHW3J3W0GQR1XS
SNU-C2B NWrhd3ZVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFPYbW1KSzVyPUS0Mlc6ODNizszN NXjBc|ZEW0GQR1XS
LCLC-103H MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUTJR|UxRTR2Lki3NFMh|ryP MmSxV2FPT0WU
U-87-MG M3PkRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NX7VcG9kUUN3ME20OU4yODJ{IN88US=> MVLTRW5ITVJ?
HAL-01 NYHZNGtiT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF3pPVdKSzVyPUS1MlE{PzlizszN NGG4RoVUSU6JRWK=
OVCAR-8 MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVLTfVF4UUN3ME20OU4{PTZ2IN88US=> M{KweXNCVkeHUh?=
KYSE-150 MlflS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkX5TWM2OD12Nz6xNFUzKM7:TR?= NU\B[|BZW0GQR1XS
OE33 MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUDJR|UxRTR5LkG0Nlkh|ryP Moj4V2FPT0WU
CAL-62 NH;BOIVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3PRRWlEPTB;NEeuOFA3QCEQvF2= MVzTRW5ITVJ?
TCCSUP M3TRVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MluyTWM2OD12Nz62NlY1KM7:TR?= M1u3[3NCVkeHUh?=
H4 M2fCe2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF;B[nVKSzVyPUS3MlY3OjFizszN MofZV2FPT0WU
CP66-MEL NYjWc496T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NI\ZeXhKSzVyPUS4MlA4ODRizszN M4KweXNCVkeHUh?=
SNB75 MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MU\JR|UxRTR6LkG4O|Qh|ryP MUTTRW5ITVJ?
Mo-T MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV3JR|UxRTR6LkK3PUDPxE1? MlPuV2FPT0WU
BT-549 NXfoSWdkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MW\JR|UxRTR6LkO3Nlkh|ryP M1PafnNCVkeHUh?=
IGR-1 NULlNHV1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkHvTWM2OD12OD62OlQ2KM7:TR?= M3;FOnNCVkeHUh?=
NCI-H1299 MlnDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXjJR|UxRTR6LkeyOFgh|ryP NXH1[m1RW0GQR1XS
ALL-PO MkSzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYjJR|UxRTR7LkmyOlgh|ryP M{LmTHNCVkeHUh?=

... Click to View More Cell Line Experimental Data

Assay
Methods Test Index PMID
Western blot
p-DNA-PKcs / DNA-PKcs / p-ATM / ATM / p-ATR / ATR / Ku70 / p-CHK1 / p-CHK2/ p-AKT / RAD51; 

PubMed: 29344644     


SUNE1 cells were irradiated with 5 Gy in the presence or absence of NU7441 (2 µM). The expression of cell cycle checkpoint proteins and double strand break repair proteins was assayed by western blot analysis at 6 or 12 h post-IR.

p-mTOR(Ser2448) / mTOR / p-S6K(Thr389); 

PubMed: 25714019     


Phosphorylation of mTOR and p70S6K were detected by Western blot analysis 24 hours after treatment.

29344644 25714019
In vivo NU7441 intraperitoneally administrated at dose of 10 mg/kg maintains for at least 4 hours shows nontoxic and increases etoposide-induced tumor growth delay 2-fold in mice bearing SW620 xenografts. [2]

Protocol

Cell Research:

[2]

- Collapse
  • Cell lines: SW620, LoVo, V3-YAC and V3 cells
  • Concentrations: 0.5 μM or 1 μM
  • Incubation Time: 17 hours
  • Method:

    The effect of NU7441 on cellular survival following exposure to etoposide, doxorubicin, and ionizing radiation is measured in SW620, LoVo, V3, and V3-YAC cells by clonogenic assays. Briefly, growing cells in six-well plates or 6-cm dishes are exposed to etoposide or doxorubicin with or without NU7441 (0.5 or 1.0 μM) for 16 hours. For radiosensitization studies, NU7441 is added to the cells 1 hour before irradiation. V3 and V3-YAC cells are exposed to γ-irradiation (3.1 Gy/min 137Cesium). SW620 and LoVo are exposed to X-irradiation (2.9 Gy/min at 230 kV, 10 mA) due to the equipment available. After irradiation, the cells are incubated with or without NU7441 for a further 16 hours. Cells are then harvested by trypsinization, counted, and seeded into 10-cm diameter Petri dishes at densities varying from 100 to 105 per dish in drug-free medium for colony formation. Colonies are stained with crystal violet after 10 to 14 days and counted with an automated colony counter. The survival reduction factor (SRF) is calculated as the surviving fraction of cells in the absence of NU7441 divided by the surviving fraction of cells in the presence of NU7441 for any given dose or concentration of cytotoxic agent. The dose modification ratio (DMR90) is calculated as the concentration/dose of cytotoxic agent required to kill 90% of the cells in the absence of NU7441 divided by the concentration/dose of cytotoxic agent required to kill 90% of the cells in the presence of NU7441.


    (Only for Reference)
Animal Research:

[2]

- Collapse
  • Animal Models: Female rude mice bearing SW620 xenografts
  • Dosages: 10 mg/kg
  • Administration: Intraperitoneally administrated
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 4 mg/mL warmed (9.67 mM)
Water Insoluble
Ethanol Insoluble
In vivo Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
5% DMSO+30% PEG 300+5% Tween 80+ddH2O
For best results, use promptly after mixing.
2mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 413.49
Formula

C25H19NO3S

CAS No. 503468-95-9
Storage powder
in solvent
Synonyms N/A
Smiles O=C1C=C(OC2=C1C=CC=C2C3=CC=CC4=C3SC5=C4C=CC=C5)N6CCOCC6

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Dosage mg/kg Average weight of animals g Dosing volume per animal ul Number of animals
Step 2: Enter the in vivo formulation (Different batches have different solubility ratios, please contact Selleck to provide you with the correct ratio)
% DMSO % % Tween 80 % ddH2O
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Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
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Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

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To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field

Frequently Asked Questions

  • Question 1:

    Could you please suggest formulations of the drug for in vivo injection?

  • Answer:

    We tested the following formulation for in vivo use, 4% DMSO+30% PEG 300+5% Tween 80+ddH2O up to 1mg/mL. It is a clear solution.

  • Question 2:

    Previous aliquots were clear and colorless while this time, it becomes yellow when the powder was dissolved in DMSO? Could you advice on this?

  • Answer:

    Slight color variation due to different processing is normal and usually doesn't interfere with the function.

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID