NU7441 (KU-57788)

Catalog No.S2638

NU7441 (KU-57788) Chemical Structure

Molecular Weight(MW): 413.49

NU7441 (KU-57788) is a highly potent and selective DNA-PK inhibitor with IC50 of 14 nM and also inhibits PI3K with IC50 of 5 μM in cell-free assays. It reduces the frequency of NHEJ while increasing the rate of HDR following Cas9-mediated DNA cleavage.

Size Price Stock Quantity  
USD 70 In stock
USD 120 In stock
USD 370 In stock
USD 970 In stock
Bulk Discount

Free Overnight Delivery on orders over $ 500
Next day delivery by 10:00 a.m. Order now.

Cited by 45 Publications

Purity & Quality Control

Choose Selective DNA-PK Inhibitors

Biological Activity

Description NU7441 (KU-57788) is a highly potent and selective DNA-PK inhibitor with IC50 of 14 nM and also inhibits PI3K with IC50 of 5 μM in cell-free assays. It reduces the frequency of NHEJ while increasing the rate of HDR following Cas9-mediated DNA cleavage.
Targets
DNA-PK [1]
(Cell-free assay)
14 nM
In vitro

NU7441 increases the persistence of γH2AX foci after ionizing radiation–induced or etoposide-induced DNA damage. NU7441 (0.5 μM or 1 μM) appreciably increases G2-M accumulation induced by ionizing radiation, etoposide, and doxorubicin in both SW620 and LoVo cells. [2] NU7441 causes persistence of doxorubicin- and ionising radiation-induced DNA double-strand break and also slightly decreases homologous recombination activity DNA-PK-proficient M059-Fus-1 and DNA-PK-deficient M059 J human tumour cells. [3] NU7441 inhibits UV-induced RPA p34 hyperphosphorylation in a dose-dependent manner both in cells lacking and cells expressing polymerase η. [4] NU7441 increases levels of fludarabine-induced γH2AX foci and correspondingly decreased fludarabine-induced cell death in chronic lymphocytic leukemia cells. [5] NU7441 also inhibits mitoxantrone-induced DNA-PKcs autophosphorylation and repair in chronic lymphocytic leukemia cells. [6] It reduces the frequency of NHEJ while increasing the rate of HDR following Cas9-mediated DNA cleavage[7].

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
NCI-H1770 MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4TyZ2lEPTB;MD6wNlE1OyEQvF2= Mk\SV2FPT0WU
A172 NILIVYxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXO4d4NWUUN3ME2wMlE2OzF4IN88US=> MXzTRW5ITVJ?
NCI-H526 NXTicnNxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NITGPXRKSzVyPUCuNlg1ODdizszN M3jpTHNCVkeHUh?=
HDLM-2 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmjiTWM2OD1yLkOyN|Q2KM7:TR?= NYf1cIxuW0GQR1XS
HuO-3N1 Mlv5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkjaTWM2OD1yLkS2OlM3KM7:TR?= NVP5cI1XW0GQR1XS
NCI-SNU-1 NILicmhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUDJR|UxRTBwNkC5PVQh|ryP MXrTRW5ITVJ?
SK-N-AS Ml;pS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVTJR|UxRTBwNkKyNVYh|ryP NYrKS29EW0GQR1XS
LoVo NYH4dlc6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1LiNWlEPTB;MD64Olc1QSEQvF2= MkfEV2FPT0WU
LAMA-84 NEDiVJJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3m4R2lEPTB;MD65PFg{OyEQvF2= MlPFV2FPT0WU
CTB-1 NILYR5VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXzRUIl4UUN3ME2xMlEyPTR4IN88US=> NFGxZ3FUSU6JRWK=
KP-N-YS MmDIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWjSXXRtUUN3ME2xMlE1OjNzIN88US=> MUHTRW5ITVJ?
HH MnmzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnX3TWM2OD1zLkG4NFk{KM7:TR?= NXPVb4R1W0GQR1XS
CHL-1 NXPRcVV{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmS3TWM2OD1zLkKxN|Y5KM7:TR?= MVrTRW5ITVJ?
NB7 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlfwTWM2OD1zLkK0O|Q2KM7:TR?= MWDTRW5ITVJ?
HL-60 NWThdIVmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mn7jTWM2OD1zLkO4NVkh|ryP MYjTRW5ITVJ?
639-V Ml7NS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoTqTWM2OD1zLkS0NVI5KM7:TR?= NH62O3hUSU6JRWK=
NCI-H1793 M1\HWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVPBTI17UUN3ME2xMlQ2QDRizszN NGHL[opUSU6JRWK=
NEC8 NEHPeppIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MULJR|UxRTFwNUWzOUDPxE1? MVHTRW5ITVJ?
PA-1 NVzCXXdnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NE[yNZdKSzVyPUGuOVgzQTRizszN M2\VRnNCVkeHUh?=
D-423MG NWn5flYzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUfy[lZXUUN3ME2xMlY6OzZzIN88US=> M{\vOXNCVkeHUh?=
NCI-H292 NFHQNY9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWriWG1YUUN3ME2xMlc1ODF|IN88US=> M{DpfHNCVkeHUh?=
SK-MEL-1 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYHHU5pNUUN3ME2xMlc6PDd7IN88US=> MUXTRW5ITVJ?
LB2241-RCC MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXrMclNTUUN3ME2yMlE1OTR4IN88US=> NGKwT4tUSU6JRWK=
SK-MEL-3 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYfJR|UxRTJwMU[0PUDPxE1? NXHaXIxvW0GQR1XS
MHH-PREB-1 MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlLKTWM2OD1{LkG2OlA6KM7:TR?= M{\rN3NCVkeHUh?=
BFTC-905 NVjoRo06T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYHJR|UxRTJwMU[2PFch|ryP MVrTRW5ITVJ?
Ramos-2G6-4C10 MlXrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlPDTWM2OD1{LkG5PVA6KM7:TR?= Mn:2V2FPT0WU
G-361 MmjuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEDhTGFKSzVyPUKuNlE3QCEQvF2= MXHTRW5ITVJ?
MOLT-4 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWDJR|UxRTJwMkG4PFgh|ryP MYLTRW5ITVJ?
DEL MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWDJR|UxRTJwM{W1OlQh|ryP MYnTRW5ITVJ?
MV-4-11 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmrDTWM2OD1{LkO3N|kh|ryP MXPTRW5ITVJ?
SK-NEP-1 NF:yUZVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHzGe|lKSzVyPUKuN|g4QDNizszN M3fhe3NCVkeHUh?=
RS4-11 NH3Oeo5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUXJR|UxRTJwNU[wNlMh|ryP NYjNcHNUW0GQR1XS
HuH-7 M1KxXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF3YUXlKSzVyPUKuOVY4ODJizszN NX36SZpNW0GQR1XS
A101D MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXixNHRFUUN3ME2yMlYyOzN6IN88US=> MkWxV2FPT0WU
KG-1 M{\LVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVXJR|UxRTJwNke5NlQh|ryP NFm3cZBUSU6JRWK=
KALS-1 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M13ZSmlEPTB;Mj62PVY{OyEQvF2= MUDTRW5ITVJ?
VMRC-RCZ M4rj[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVrhSJVPUUN3ME2yMlc4OzJ6IN88US=> NVzCdYdnW0GQR1XS
SK-UT-1 MlL5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHfKTGVKSzVyPUOuNVU{OSEQvF2= MoTyV2FPT0WU
SW962 NIG4UZRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NF;rXnNKSzVyPUOuNlA{PTJizszN NWDQVGV7W0GQR1XS
DBTRG-05MG NXTuWGl2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIfUV3BKSzVyPUOuNlgxQDVizszN MmX3V2FPT0WU
PANC-08-13 NWTJeWhVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUnyWG1HUUN3ME2zMlQyOjd6IN88US=> MXjTRW5ITVJ?
QIMR-WIL MkCwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXrZbGNPUUN3ME2zMlQyOzRzIN88US=> Mnj2V2FPT0WU
SK-MEL-30 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYTJR|UxRTNwNEK1PVgh|ryP NELT[2FUSU6JRWK=
697 Mk[4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NE\iSWJKSzVyPUOuOFQ6QTNizszN MXvTRW5ITVJ?
NY MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MULJR|UxRTNwNEWwNlIh|ryP NGnuV2NUSU6JRWK=
ES7 Ml3TS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnnvTWM2OD1|LkS2O|I6KM7:TR?= Mn;EV2FPT0WU
JVM-3 M{DKNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NE\OUoNKSzVyPUOuOFgxPzdizszN MkHPV2FPT0WU
U031 MkTFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NY\6[YV6UUN3ME2zMlU6OzZ6IN88US=> NYjDW2dGW0GQR1XS
BHT-101 M4XRUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoDkTWM2OD1|LkW5PVg2KM7:TR?= NVHtN3d6W0GQR1XS
8305C NWTTN2NUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHjOWVJKSzVyPUOuOlE4OzZizszN MYTTRW5ITVJ?
MG-63 NYDmXmFGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NW\XbmptUUN3ME2zMlYzPjd4IN88US=> NE\yfGdUSU6JRWK=
NOS-1 MoPzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1j2RWlEPTB;Mz62OVMyOiEQvF2= M1;lTXNCVkeHUh?=
YH-13 NXz1UYNWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXrJR|UxRTNwOEexPFkh|ryP MVfTRW5ITVJ?
LXF-289 M{PaT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGPHc3JKSzVyPUOuPVExPDFizszN NEG2do9USU6JRWK=
GOTO M1\xSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIr3WHlKSzVyPUOuPVE1QSEQvF2= NIi3dVlUSU6JRWK=
EKVX MmLDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4XlXWlEPTB;ND6yNlUzPCEQvF2= NH\JR4VUSU6JRWK=
CAL-51 NIHOU|JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX;JR|UxRTRwMkS4OVQh|ryP MXTTRW5ITVJ?
AN3-CA M4S0fGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUDJR|UxRTRwMkW4NVMh|ryP NIfnZ|hUSU6JRWK=
IA-LM M3Hodmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{XmU2lEPTB;ND6yO|k{PSEQvF2= Mnm2V2FPT0WU
KU-19-19 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml24TWM2OD12LkOyPVIyKM7:TR?= MVrTRW5ITVJ?
A704 MnHKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M17IWGlEPTB;ND60NFg5QCEQvF2= NYH0flV1W0GQR1XS
RH-18 Mo\HS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUjrfVhXUUN3ME20MlQ1QTV|IN88US=> MYjTRW5ITVJ?
IST-MEL1 M2C4e2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4i1XWlEPTB;ND61PFI3OyEQvF2= M2fmUHNCVkeHUh?=
LU-134-A NID0e4JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3H3d2lEPTB;ND61PVY5PSEQvF2= M4DJc3NCVkeHUh?=
SF126 NX3X[G1xT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYPJR|UxRTRwNkC3NVUh|ryP NVnNbZVyW0GQR1XS
EFO-27 NFHjOFRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Ml:1TWM2OD12Lk[2OVI2KM7:TR?= NGnue5RUSU6JRWK=
SN12C NH74VWNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoDVTWM2OD12LkexPFk5KM7:TR?= NFTUNnNUSU6JRWK=
L-363 MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkH6TWM2OD12Lke3NVE3KM7:TR?= M4TyXXNCVkeHUh?=
MEL-HO NX7SVopRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGPsb4lKSzVyPUSuO|c6QDlizszN NFzIOo1USU6JRWK=
TYK-nu NWWzXZo6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NECxTHdKSzVyPUSuPFAyOjhizszN MVvTRW5ITVJ?
MDA-MB-415 MofTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3zKNGlEPTB;NT6wNFMyPCEQvF2= MmnoV2FPT0WU
HCC70 MmLwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWnv[Xk3UUN3ME21MlA{QTN7IN88US=> MULTRW5ITVJ?
IGROV-1 NEfEWHVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4j6W2lEPTB;NT6yOVI6OiEQvF2= MlXsV2FPT0WU
NCI-H1355 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFvCTXlKSzVyPUWuNlk3KM7:TR?= M2HDcnNCVkeHUh?=
23132-87 NGrsXVNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4jFTGlEPTB;NT6zNlAzPCEQvF2= NY\FPVZqW0GQR1XS
NB69 NXTwbmE4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWPJR|UxRTVwM{K0NkDPxE1? MYDTRW5ITVJ?
HSC-2 NFjqUmFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUTLTZJGUUN3ME21MlQyPzd|IN88US=> NEPrO3BUSU6JRWK=
KYSE-410 NU\LZm1JT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYjJR|UxRTVwNEe2N|Yh|ryP MYXTRW5ITVJ?
GCIY NITFOpdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3rkT2lEPTB;NT61NVM4QCEQvF2= MnLvV2FPT0WU
A427 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlKwTWM2OD13LkWzOlYyKM7:TR?= NXrRNYdJW0GQR1XS
ChaGo-K-1 M{XpTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYDJR|UxRTVwNU[1PVkh|ryP M1jFenNCVkeHUh?=
PFSK-1 MlnnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUPJR|UxRTVwNkKxPVQh|ryP M2XhNHNCVkeHUh?=
MLMA NX71dJhnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml3sTWM2OD13LkizOlA3KM7:TR?= NVHOfpJXW0GQR1XS
RVH-421 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYDJR|UxRTZwMEezN|gh|ryP NIPWd2dUSU6JRWK=
LB1047-RCC NXPLfW9PT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYS0UlJXUUN3ME22MlE4PTJ{IN88US=> M3HSW3NCVkeHUh?=
MHH-NB-11 M3W3NGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEH2UY9KSzVyPU[uN|I4OjFizszN NXzXcnJQW0GQR1XS
J-RT3-T3-5 M1G4NGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXfJR|UxRTZwNkOyPVEh|ryP NVnBW4FNW0GQR1XS
UM-UC-3 NFfx[ZlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn:5TWM2OD14Lk[0N|M1KM7:TR?= MYXTRW5ITVJ?
IST-SL1 MmjGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2nvNWlEPTB;Nj62PVM3QSEQvF2= MoPqV2FPT0WU
NB14 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGfWOHFKSzVyPU[uO|k4PjFizszN NWDPU2l[W0GQR1XS
NBsusSR MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVXVR5VLUUN3ME22MlgzPTB{IN88US=> M3r0eXNCVkeHUh?=
D-263MG MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYLuRZBGUUN3ME22MlkyODZ6IN88US=> NIXGbGxUSU6JRWK=
NCI-H2347 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUCwUpRRUUN3ME22Mlk{OjF|IN88US=> Mln3V2FPT0WU
ES8 NUTRNJJST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlrKTWM2OD14Lkm3OVg5KM7:TR?= MXnTRW5ITVJ?
786-0 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWHqOms5UUN3ME23MlA6Pzh4IN88US=> MXHTRW5ITVJ?
EPLC-272H MmPtS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXzJR|UxRTdwMU[yOFYh|ryP MXzTRW5ITVJ?
CAPAN-1 M4TSZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFLXVJVKSzVyPUeuNlQ{PTlizszN Ml\qV2FPT0WU
NCI-H82 MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHHUbFlKSzVyPUeuNlY3PTlizszN NYHhVVh[W0GQR1XS
G-402 MoD0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFXGZVlKSzVyPUeuN|AxPTFizszN M1PvO3NCVkeHUh?=
SW982 M4\JbGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYLaUGxHUUN3ME23MlMxOjB|IN88US=> NH\mfYNUSU6JRWK=
OVCAR-4 M4nYSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml\mTWM2OD15LkOxN|I5KM7:TR?= MYjTRW5ITVJ?
KARPAS-299 NUi3OINZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEPIU49KSzVyPUeuN|I3OjJizszN M4rUU3NCVkeHUh?=
MIA-PaCa-2 NX\OXm1nT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUHJR|UxRTdwM{[4NlMh|ryP M4fUbnNCVkeHUh?=
AU565 NV3CNolXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlnYTWM2OD15LkW5PFM{KM7:TR?= NVX4dmRQW0GQR1XS
GAMG M1i2Smdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWTJR|UxRTdwNkSxN|Eh|ryP M1Tld3NCVkeHUh?=
HuO9 M4frSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkjxTWM2OD15LkexO|Q{KM7:TR?= MlmwV2FPT0WU
ACN MlTzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{L5PGlEPTB;Nz63OFM{KM7:TR?= NV\6dFI{W0GQR1XS
RO82-W-1 NHfFWXhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX\Te|F7UUN3ME23Mlc1PTN|IN88US=> MYHTRW5ITVJ?
NKM-1 M1q4cmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2LGeGlEPTB;Nz63OFk2PSEQvF2= MV7TRW5ITVJ?
CAL-12T M1XPZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NU\O[5kzUUN3ME23Mlk1OzV{IN88US=> MnfkV2FPT0WU
FADU NGTjZ5ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYPJR|UxRThwMEO2OVQh|ryP MlGzV2FPT0WU
NCI-H28 MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2nGemlEPTB;OD6xOlk3OiEQvF2= NF;ofWFUSU6JRWK=
LCLC-97TM1 MmPvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHu4VHpKSzVyPUiuNlEyOjJizszN NGXld2hUSU6JRWK=
CHP-134 M2XrdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3r0V2lEPTB;OD6yOFE5PSEQvF2= NE\idHhUSU6JRWK=
HT-1080 NWT6bJlQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{H6NGlEPTB;OD6yOVA6OyEQvF2= MWfTRW5ITVJ?
PC-3 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXL4Tpc6UUN3ME24MlI4Ozl{IN88US=> NELldm9USU6JRWK=
SNU-449 NX:2fnk6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{LwOWlEPTB;OD6yO|k{KM7:TR?= NWe5cWZxW0GQR1XS
VA-ES-BJ M4\Tfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlTkTWM2OD16LkO0Olg3KM7:TR?= NInI[2NUSU6JRWK=
HT NYnuZpJRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MorUTWM2OD16LkO2OFkh|ryP NGHCWWpUSU6JRWK=
HOS NWPNXFkyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXfzZ4t4UUN3ME24MlM4PTh7IN88US=> M3r2bnNCVkeHUh?=
KNS-62 NGnsTI5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWPJR|UxRThwM{e3OlIh|ryP MmT4V2FPT0WU
OAW-42 M3vHSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{XhN2lEPTB;OD65OVk3PCEQvF2= NVPwemhyW0GQR1XS
A549 NULWXWhpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGjzW4hKSzVyPUmuNFk3OTJizszN MXzTRW5ITVJ?
CAKI-1 MoXHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3fJXGlEPTB;OT6xOlYyKM7:TR?= MUDTRW5ITVJ?
HCC1937 M2LnSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVzJR|UxRTlwNkm4OlUh|ryP NYLuOmpYW0GQR1XS
GI-ME-N NU\YZZlXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NW\QcIV{UUN3ME25MlcxOTN5IN88US=> MljmV2FPT0WU
DU-4475 MmCwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWnJR|UxRTlwOU[5N|kh|ryP NE\v[Y9USU6JRWK=
EM-2 NEjlOHhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWPwW3d6UUN3ME2xNE4zPDJ4IN88US=> NYOyZoF3W0GQR1XS
NCI-H1755 NEnmVG9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVXJR|UxRTFyLkK0Nlgh|ryP MljHV2FPT0WU
NCI-H1437 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnPZTWM2OD1zMD61O|I2KM7:TR?= MofMV2FPT0WU
VM-CUB-1 MnK3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2fpSmlEPTB;MUCuOlE3PCEQvF2= MWDTRW5ITVJ?
A2058 NHnzT2ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NY\lcYU2UUN3ME2xNE43PDB2IN88US=> M1\QSnNCVkeHUh?=
BPH-1 MoDuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVHJR|UxRTFyLkexOFUh|ryP MnW4V2FPT0WU
NB5 NYDMXXlmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFjCeIZKSzVyPUGwMlc2PTlizszN NVLXenlLW0GQR1XS
G-401 NGnZOmNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUHQcY8zUUN3ME2xNE44PjJ4IN88US=> MVvTRW5ITVJ?
CAL-72 M{P1Zmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NI\k[5VKSzVyPUGwMlgxQTRizszN MVnTRW5ITVJ?
SK-MEL-28 NXHhNmx6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVrJR|UxRTFyLkiyNFIh|ryP NUPnd3BDW0GQR1XS
C32 MlixS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIXl[FJKSzVyPUGwMlg{PDdizszN MVXTRW5ITVJ?
NCI-H1155 MkLmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIjFeHlKSzVyPUGwMlg{PzZizszN Mn7LV2FPT0WU
BB49-HNC NWDrTmZ3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWXJR|UxRTFyLki1PFYh|ryP MVfTRW5ITVJ?
GMS-10 NWfDXGxsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1;DZWlEPTB;MUCuPFk4OSEQvF2= NH\NTVNUSU6JRWK=
K5 M{Twemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXrJR|UxRTFyLkmwO|Eh|ryP NEXJeZpUSU6JRWK=
OS-RC-2 MkjRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGH4[JVKSzVyPUGxMlA2PTlizszN NGHBNY1USU6JRWK=
HTC-C3 Mlj1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn\KTWM2OD1zMT6wO|E1KM7:TR?= M3fwb3NCVkeHUh?=
LB996-RCC M{\5NWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV36em5ZUUN3ME2xNU4xPzJ|IN88US=> MYDTRW5ITVJ?
NCI-H1563 NUnHZYdLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVLJR|UxRTFzLkGwNVEh|ryP MXLTRW5ITVJ?
CAL-54 MlPoS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2rXNWlEPTB;MUGuOFgyOSEQvF2= Mn\PV2FPT0WU
WM-115 NYDEZnVrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1G1fGlEPTB;MUGuOlgzPCEQvF2= NG\DO5dUSU6JRWK=
COLO-684 M1i5R2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlnkTWM2OD1zMT63NlY4KM7:TR?= MYfTRW5ITVJ?
HOP-62 NILSWWpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MY\JR|UxRTFzLke1NFgh|ryP M4POVHNCVkeHUh?=
NCI-H650 MmXRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYXJR|UxRTFzLki5OlEh|ryP MULTRW5ITVJ?
TE-11 NX\LOFI3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEXzSYlKSzVyPUGxMlk{OTVizszN MUHTRW5ITVJ?
COLO-679 NYT2WFZ4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoP6TWM2OD1zMT65OFYh|ryP M1jqR3NCVkeHUh?=
FTC-133 MnnYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkS0TWM2OD1zMj6wNFc3KM7:TR?= NUni[mgyW0GQR1XS
D-283MED MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFm2W3FKSzVyPUGyMlA2PjlizszN NWrScW9oW0GQR1XS
SK-PN-DW MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVjaSWZRUUN3ME2xNk4yQTB{IN88US=> M{fQWnNCVkeHUh?=
BALL-1 MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWjs[XpyUUN3ME2xNk4zPjZ{IN88US=> MkHLV2FPT0WU
GT3TKB MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF;kRXFKSzVyPUGyMlMxPzRizszN NVi5SYpHW0GQR1XS
HOP-92 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWTaeWhFUUN3ME2xNk42OjN|IN88US=> NGP1W3dUSU6JRWK=
M14 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml7HTWM2OD1zMz6wN|M2KM7:TR?= MUXTRW5ITVJ?
SKG-IIIa NYn4UlZ5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIKyTZNKSzVyPUGzMlA2PTRizszN MYHTRW5ITVJ?
Becker M{PDemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV;JR|UxRTF|LkC1PEDPxE1? M2TGd3NCVkeHUh?=
ES5 NWPtbVlJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVvucotCUUN3ME2xN{4yOzV4IN88US=> MXfTRW5ITVJ?
NCI-H2030 NYThUY9NT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYHJR|UxRTF|LkKwOlIh|ryP M{LyPXNCVkeHUh?=
SNU-423 MorJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlTZTWM2OD1zMz6zPFEh|ryP NFfWTlhUSU6JRWK=
CP50-MEL-B M3\rTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHvPV3JKSzVyPUGzMlYzOzJizszN MV\TRW5ITVJ?
NCI-H1092 M2\6fWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVu4d4xVUUN3ME2xN{44PDd3IN88US=> M1P6RnNCVkeHUh?=
8-MG-BA NXrRfIJjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mn7WTWM2OD1zMz63OVE{KM7:TR?= M1LRd3NCVkeHUh?=
CAL-27 MkTHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVHJR|UxRTF2LkC3Nlch|ryP NY\WPYFmW0GQR1XS
AGS NWHNe3lKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MV;JR|UxRTF2LkGzNVkh|ryP M3TPbXNCVkeHUh?=
MZ2-MEL MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mo[3TWM2OD1zND6xOFg5KM7:TR?= NFvEe3dUSU6JRWK=
BFTC-909 NWSyenMyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml[3TWM2OD1zND61NFU2KM7:TR?= MnjTV2FPT0WU
D-566MG M2\VOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3\3bGlEPTB;MUSuO|cxPiEQvF2= NVfGU|g4W0GQR1XS
MZ7-mel NFXNcXlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlXpTWM2OD1zNT6xNFY4KM7:TR?= NYPYV3dGW0GQR1XS
TE-5 NVva[HV5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUPJR|UxRTF3LkKzN|Mh|ryP NGXhRWlUSU6JRWK=
647-V MmGwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4K4OGlEPTB;MUWuNlcxPSEQvF2= NV3URWFZW0GQR1XS
DMS-114 M3jYOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVjJR|UxRTF3LkOyPVEh|ryP M1uydHNCVkeHUh?=
ME-180 NV\NZZVET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MY\JR|UxRTF3LkS3PFMh|ryP M3TNNnNCVkeHUh?=
MS-1 M2XIfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVTJR|UxRTF3LkW2NlMh|ryP MkLSV2FPT0WU
NUGC-3 M{[wemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVzJR|UxRTF3Lk[yOFUh|ryP NWXTfHhLW0GQR1XS
GB-1 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4j1OWlEPTB;MUWuOlQ{PyEQvF2= NG[xcW5USU6JRWK=
LOXIMVI Ml\tS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWTQZ2FpUUN3ME2xOU45QTF7IN88US=> NEGzWllUSU6JRWK=
NCI-H1304 NFHBXZhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFLpbIFKSzVyPUG1Mlg6OjhizszN M1S1b3NCVkeHUh?=
KURAMOCHI NF:wSWtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3XTdWlEPTB;MUWuPVcyKM7:TR?= NV[xbZpzW0GQR1XS
SW1783 MkLaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVjJR|UxRTF4LkC5PVMh|ryP NELnVGRUSU6JRWK=
EGI-1 MoHPS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mk\MTWM2OD1zNj61N|Y2KM7:TR?= NITJW2VUSU6JRWK=
KGN M2rZdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUHJR|UxRTF4LkW1PFYh|ryP NXW2eHQ3W0GQR1XS
PANC-03-27 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV7JR|UxRTF4Lke2OlIh|ryP MUHTRW5ITVJ?
RH-1 M3n5TGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGLxOYlKSzVyPUG2MlgzPSEQvF2= MXTTRW5ITVJ?
HT-1376 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NETuRVZKSzVyPUG2Mlg1PDZizszN NFvHbndUSU6JRWK=
ZR-75-30 M{OwNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1\EbGlEPTB;MU[uPVM3OSEQvF2= NHLZXHZUSU6JRWK=
TI-73 M{Xxemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFzsUpRKSzVyPUG2Mlk1ODhizszN NIO5c5FUSU6JRWK=
TK10 NE\3SGFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYPJR|UxRTF5LkCwO|kh|ryP Mln0V2FPT0WU
SW684 NHTRb41Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoP0TWM2OD1zNz6wNVU1KM7:TR?= NFzvXlhUSU6JRWK=
RPMI-8866 NFPxWGdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1TkNWlEPTB;MUeuNFY6QSEQvF2= NEHCdlVUSU6JRWK=
LNCaP-Clone-FGC M{OxO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIfqbJBKSzVyPUG3MlUzODFizszN MWXTRW5ITVJ?
NCI-H2291 M4n4SGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3nEcGlEPTB;MUiuOFM1PSEQvF2= MofPV2FPT0WU
T47D NV\VbmVjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYWwUWlqUUN3ME2xPE41QDhizszN NUnaUYlJW0GQR1XS
A204 Ml3tS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnnNTWM2OD1zOD61OFUzKM7:TR?= NGjsTmtUSU6JRWK=
HT-144 NHfEfHJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIO1T|RKSzVyPUG4Mlc1OjdizszN Mnu3V2FPT0WU
MDA-MB-361 NYXKOIFTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2rmSWlEPTB;MUmuNFcyPCEQvF2= MY\TRW5ITVJ?
HCC1806 NEnXUpRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXzJR|UxRTF7LkG1PVEh|ryP MmHCV2FPT0WU
NCI-H596 MmHNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV\JR|UxRTF7Lk[zPVEh|ryP NHfPXFFUSU6JRWK=
K-562 Mm[xS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXXLUI9QUUN3ME2xPU45QTJ4IN88US=> NIrUVndUSU6JRWK=
D-336MG MmT3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1\QNmlEPTB;MUmuPVMzOiEQvF2= NI[5V|hUSU6JRWK=
SK-MEL-2 M4fPfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF[wWJdKSzVyPUKwMlE2PTlizszN NYHWNnA{W0GQR1XS
HEC-1 NELYZ2ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH3SSW5KSzVyPUKwMlQ6PzhizszN MnjKV2FPT0WU
EW-13 NEGxUXBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1XVTGlEPTB;MkCuOVQ1OyEQvF2= MY\TRW5ITVJ?
Hs-578-T NF\4UWxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NW\KbIhyUUN3ME2yNE42PTh|IN88US=> Mk\GV2FPT0WU
SJSA-1 M4jnbWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{C0[2lEPTB;MkCuOVY5QCEQvF2= MX;TRW5ITVJ?
RCC10RGB MkTFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4LZXmlEPTB;MkCuOlcyQSEQvF2= MVjTRW5ITVJ?
LAN-6 NITScnhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIP5Z4xKSzVyPUKxMlA{QTZizszN Mn[1V2FPT0WU
NCI-H1048 NH\VTXRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmX2TWM2OD1{MT6yNlU5KM7:TR?= MWTTRW5ITVJ?
CW-2 MmnrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NW\ke5ByUUN3ME2yNU4zPzB3IN88US=> MWjTRW5ITVJ?
HCC2157 MoDSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2G4TmlEPTB;MkGuN|Yh|ryP M4LZdnNCVkeHUh?=
EW-22 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4n4W2lEPTB;MkGuN|c3KM7:TR?= NXvWfWI5W0GQR1XS
A253 M4joOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml;WTWM2OD1{MT60OFgyKM7:TR?= M1zDZ3NCVkeHUh?=
BE-13 NVf3V25oT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH\5Zo9KSzVyPUKxMlYyOTNizszN M4T1O3NCVkeHUh?=
KINGS-1 MlewS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH\oZVJKSzVyPUKxMlY{OTZizszN NYjaT3ZUW0GQR1XS
ETK-1 NWLpeJY6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4fzUmlEPTB;MkGuPFE2OiEQvF2= NXyxfmN2W0GQR1XS
NCI-H2452 NYTGNpJZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXzJR|UxRTJzLki2OFch|ryP NGTKdFBUSU6JRWK=
HPAF-II NUTqOJNTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2CzNWlEPTB;MkGuPFkzOyEQvF2= NH3vSI5USU6JRWK=
D-542MG NYfJRnB5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHrZ[4VKSzVyPUKxMlkxPjlizszN MUnTRW5ITVJ?
NCI-H630 NYDMVG0zT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWjl[|Z1UUN3ME2yNk4xOjl4IN88US=> M3j2UnNCVkeHUh?=
TGBC11TKB NFL4RmhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEfHR2JKSzVyPUKyMlA1QSEQvF2= NVW3cWZuW0GQR1XS
BCPAP NFvSXo9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4\MZmlEPTB;MkKuOlEyKM7:TR?= MlvEV2FPT0WU
HLE MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFO4c5FKSzVyPUKyMlY6PyEQvF2= NYKzeoFyW0GQR1XS
NCI-H727 NX[xPJZ6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX\JR|UxRTJ{LkezOUDPxE1? NVXkO3IxW0GQR1XS
RD NWftUo84T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4rpTmlEPTB;MkKuO|UyQCEQvF2= NUew[ZVYW0GQR1XS
NCI-H522 MmDLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFXKWllKSzVyPUKyMlg1OzFizszN MXLTRW5ITVJ?
CGTH-W-1 M2\oeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NY\j[2drUUN3ME2yN{4xPjRzIN88US=> M{KyT3NCVkeHUh?=
SK-LU-1 NXXiPHdCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHS4ToFKSzVyPUKzMlQ3QDNizszN MX\TRW5ITVJ?
BB65-RCC NWHYPXVzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFnafGlKSzVyPUKzMlc5PjNizszN NF\kcopUSU6JRWK=
HSC-3 M4rPZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWn3bGExUUN3ME2yN{45PTJ5IN88US=> Ml23V2FPT0WU
SK-MES-1 NGPWSpVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEjHVVlKSzVyPUK0MlAyPjFizszN MluxV2FPT0WU
DB NV\2dmUyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXfJR|UxRTJ2LkGwNlgh|ryP MXLTRW5ITVJ?
HO-1-N-1 M3X1c2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFvLWJFKSzVyPUK0MlMxQTNizszN MXLTRW5ITVJ?
MKN1 Ml;tS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NY\WS2YyUUN3ME2yOE43QCEQvF2= MXzTRW5ITVJ?
MN-60 M{LBfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHXuZ2FKSzVyPUK0Mlg2OTlizszN Mn3KV2FPT0WU
8505C NFHocGdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{LhXWlEPTB;MkWuNVg1PSEQvF2= MlrNV2FPT0WU
COLO-320-HSR NUP4WlV6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NELqe2lKSzVyPUK1MlIzODhizszN M2\ZSXNCVkeHUh?=
BB30-HNC NXvGOVJxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4PwemlEPTB;MkWuNlQ5OyEQvF2= NXLiWmJlW0GQR1XS
KM12 MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{LGcGlEPTB;MkWuOVgxPyEQvF2= NFTxXodUSU6JRWK=
NB13 NFvpS4VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWHJR|UxRTJ3LkW4PVgh|ryP NGG4WVlUSU6JRWK=
HCC2998 NXmwOVV1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVuzN4dDUUN3ME2yOk4xOjh|IN88US=> MYrTRW5ITVJ?
U-118-MG NWS3NGRwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{\uOmlEPTB;Mk[uNFgxQCEQvF2= NFvJfFlUSU6JRWK=
NB10 NUW0bHBsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHHDXotKSzVyPUK2MlI{PCEQvF2= NXXnXXRvW0GQR1XS
SK-LMS-1 MlnpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGjoPG5KSzVyPUK3MlA4ODRizszN NWTDNmpmW0GQR1XS
SW1573 M{HjfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVHJR|UxRTJ5LkGxJO69VQ>? MmL2V2FPT0WU
LB373-MEL-D NHXaNopIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{mzfGlEPTB;MkeuNVI6PCEQvF2= MoX3V2FPT0WU
DK-MG MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2DIcWlEPTB;MkeuNVgyPyEQvF2= MVnTRW5ITVJ?
RMG-I MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFzhXWRKSzVyPUK3MlIxOjlizszN MVjTRW5ITVJ?
SW1088 MonWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVPJR|UxRTJ5LkWwOFIh|ryP MkjpV2FPT0WU
SK-OV-3 NFXUT|RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlLkTWM2OD1{Nz63OVk{KM7:TR?= MVzTRW5ITVJ?
KP-N-YN MoXsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4XKNmlEPTB;MkeuPFA1OyEQvF2= M{XQVHNCVkeHUh?=
RPMI-7951 NEPHemFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2fGOGlEPTB;MkiuNlQ2PiEQvF2= Mly5V2FPT0WU
CaR-1 NIf4e5RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmXvTWM2OD1{OD61OVgzKM7:TR?= M2XtbnNCVkeHUh?=
MKN7 MmfPS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIK3UXZKSzVyPUK4MlU6PjRizszN NGr6cZVUSU6JRWK=
CHP-212 MlmyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEnXOYRKSzVyPUK4Mlc1ODFizszN NH64d|BUSU6JRWK=
KYSE-450 NFr4XHlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1T0fWlEPTB;MkiuPFA6OSEQvF2= M2T4PHNCVkeHUh?=
RXF393 MmnOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFHjVYZKSzVyPUK5MlI6ODZizszN NG\QNXlUSU6JRWK=
P30-OHK MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWr0SoZIUUN3ME2yPU4{ODR6IN88US=> NWr0WpBmW0GQR1XS
Ca9-22 MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIeyTZpKSzVyPUK5MlQzQTlizszN NVHLZpR7W0GQR1XS
RT-112 NUW1O4FRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVjxcmxJUUN3ME2yPU41PjFzIN88US=> M3vHdXNCVkeHUh?=
ES1 NUDHWJlbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH:2dXlKSzVyPUK5Mlg2PDRizszN MULTRW5ITVJ?
HCE-4 NXfUW|hwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoGxTWM2OD1{OT64O|g3KM7:TR?= Mli3V2FPT0WU
AM-38 MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlvYTWM2OD1|MD6wOlA3KM7:TR?= MlnYV2FPT0WU
AsPC-1 NXzP[ZM2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXzJR|UxRTNyLkiwOVMh|ryP M1jKU3NCVkeHUh?=
TE-9 MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYDJR|UxRTNyLki3N|ch|ryP MoX0V2FPT0WU
HuP-T4 NHuzUpJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVPMVZh{UUN3ME2zNE46PjN6IN88US=> NYHSUGhkW0GQR1XS
LB2518-MEL NH[ySVlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{jRUWlEPTB;M{GuNFc1PCEQvF2= M1HmXXNCVkeHUh?=
NCI-H1703 Ml3sS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXHJR|UxRTNzLkC5NFUh|ryP MVLTRW5ITVJ?
NCI-H2228 M3L1WGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2nzUGlEPTB;M{GuOFY2OSEQvF2= MUTTRW5ITVJ?
SCC-4 NFPufFZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWnlRZlWUUN3ME2zNU46OThzIN88US=> M3LvfHNCVkeHUh?=
KNS-81-FD MmTES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWXJR|UxRTN{LkCxNlgh|ryP MXLTRW5ITVJ?
NTERA-S-cl-D1 NH;ZXZJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXvJR|UxRTN{LkC3N|kh|ryP M3HPeHNCVkeHUh?=
Daoy NYrtO2xZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3eyO2lEPTB;M{KuNFg{QCEQvF2= NUPGNZNbW0GQR1XS
ES4 Mli2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHXsXI5KSzVyPUOyMlM6OjJizszN NVH0[2lTW0GQR1XS
MHH-ES-1 M2jEc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXnCXIgxUUN3ME2zNk41QDd{IN88US=> MULTRW5ITVJ?
C-33-A MmP1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoCwTWM2OD1|Mj63O|I5KM7:TR?= MYDTRW5ITVJ?
BHY NF;B[XhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFHCeWZKSzVyPUOyMlk1QTVizszN NYPIZphZW0GQR1XS
Detroit562 Mnv0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4rOVWlEPTB;M{OuOlY2PyEQvF2= NGWwcWNUSU6JRWK=
EW-1 MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NH3NcZJKSzVyPUOzMlk{OjJizszN NEnyTYdUSU6JRWK=
NCI-H1395 MonuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHTpWmhKSzVyPUO0MlA4QTlizszN MUnTRW5ITVJ?
KM-H2 M{DvVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXXJR|UxRTN4LkS3OFMh|ryP MonZV2FPT0WU
NCI-H520 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXXZcIt3UUN3ME2zOk44PTRzIN88US=> Ml7yV2FPT0WU
D-392MG NWrITWt[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYn3bJhOUUN3ME2zO{4{OzR2IN88US=> M{fobHNCVkeHUh?=
NOMO-1 NGjoVZFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmL4TWM2OD1|Nz64NFg6KM7:TR?= NITqNJVUSU6JRWK=
TE-6 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{nhV2lEPTB;M{iuNVI1KM7:TR?= NYPiVXZlW0GQR1XS
HT-3 NVTqdIJkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWrselFDUUN3ME2zPE41PDN4IN88US=> M1vJfnNCVkeHUh?=
RPMI-8226 M4XBbWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXfJR|UxRTN6Lkm1NVkh|ryP M37tS3NCVkeHUh?=
U251 MoS4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4[1XWlEPTB;M{muNFEzPCEQvF2= M1O2XXNCVkeHUh?=
GCT NHLlSoZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFrEb2lKSzVyPUO5MlE5PTJizszN MYDTRW5ITVJ?
A431 NITGS2pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVfJR|UxRTN7LkG4PVQh|ryP M4XqXXNCVkeHUh?=
TE-12 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVPJR|UxRTN7LkK0OFgh|ryP Ml7aV2FPT0WU
HMV-II MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVTJR|UxRTN7LkWwOFch|ryP MkDrV2FPT0WU
IST-MES1 MlTiS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHe4[HdKSzVyPUSwMlE2ODJizszN NFPHdoxUSU6JRWK=
SW13 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWLDNodkUUN3ME20NE42OTlizszN NWD5dJR3W0GQR1XS
SF295 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1rvcmlEPTB;NECuPFA3PiEQvF2= MX\TRW5ITVJ?
MDA-MB-157 MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEPxNmNKSzVyPUSwMlk1PjJizszN MnvTV2FPT0WU
TE-1 NE\kWoZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYe2TVI3UUN3ME20NU45PzF2IN88US=> NFXaWmRUSU6JRWK=
HuCCT1 NV3xdYVOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGnu[YFKSzVyPUSyMlUzQDlizszN NH\KNXlUSU6JRWK=
KYSE-510 NXzMfYJUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{DyOmlEPTB;NEOuNVc2PCEQvF2= NH7pempUSU6JRWK=
NCI-H358 M1TzeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M37ZUWlEPTB;NESuNFMxPCEQvF2= NXHJZY1vW0GQR1XS
SW900 NX\Zb5h6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVjJR|UxRTR2LkC3OVgh|ryP M1HJZXNCVkeHUh?=
CAS-1 NWK5OmNuT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVnJR|UxRTR2LkC5PVEh|ryP NEWwTG5USU6JRWK=
TE-8 NGn2VFRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFzMepNKSzVyPUS0MlU3PThizszN NV63dJptW0GQR1XS
P12-ICHIKAWA Ml\jS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlqwTWM2OD12ND62NVEzKM7:TR?= M4X6O3NCVkeHUh?=
YKG-1 MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHnseVNKSzVyPUS0Mlc5OSEQvF2= M3fRXXNCVkeHUh?=
SNU-C2B MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXzCO2RRUUN3ME20OE44QTB|IN88US=> MnzlV2FPT0WU
LCLC-103H MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXniXlBUUUN3ME20OE45PzB|IN88US=> MXLTRW5ITVJ?
U-87-MG M1frSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4rmU2lEPTB;NEWuNVAzOiEQvF2= M1L3VHNCVkeHUh?=
HAL-01 M4jlOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NH;3dIxKSzVyPUS1MlE{PzlizszN NFXJV3JUSU6JRWK=
OVCAR-8 NF[0NIFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYrVbmo6UUN3ME20OU4{PTZ2IN88US=> MlWyV2FPT0WU
KYSE-150 MnuwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{WwXmlEPTB;NEeuNVA2OiEQvF2= MVLTRW5ITVJ?
OE33 MonNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1\vVGlEPTB;NEeuNVQzQSEQvF2= NXHiRYRGW0GQR1XS
CAL-62 MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEXSRXhKSzVyPUS3MlQxPjhizszN M2i3S3NCVkeHUh?=
TCCSUP MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4DEdmlEPTB;NEeuOlI3PCEQvF2= NUnafldEW0GQR1XS
H4 NX;3XGlbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYrG[3l7UUN3ME20O{43PjJzIN88US=> NIj0UG9USU6JRWK=
CP66-MEL NWjRUZQ{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3nPfmlEPTB;NEiuNFcxPCEQvF2= NEjWVYVUSU6JRWK=
SNB75 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEH4T|BKSzVyPUS4MlE5PzRizszN NVmxenFkW0GQR1XS
Mo-T NH62dVRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVnXVWNSUUN3ME20PE4zPzlizszN NXvWdYVbW0GQR1XS
BT-549 NVixS|RWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoHtTWM2OD12OD6zO|I6KM7:TR?= MV7TRW5ITVJ?
IGR-1 NYGwS|AxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmjPTWM2OD12OD62OlQ2KM7:TR?= NV7jfoFpW0GQR1XS
NCI-H1299 NHXRXGVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYTJR|UxRTR6LkeyOFgh|ryP Mlj0V2FPT0WU
ALL-PO NVTOWoJbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1K0W2lEPTB;NEmuPVI3QCEQvF2= NFjCNo9USU6JRWK=

... Click to View More Cell Line Experimental Data

Assay
Methods Test Index PMID
Western blot
p-DNA-PKcs / DNA-PKcs / p-ATM / ATM / p-ATR / ATR / Ku70 / p-CHK1 / p-CHK2/ p-AKT / RAD51; 

PubMed: 29344644     


SUNE1 cells were irradiated with 5 Gy in the presence or absence of NU7441 (2 µM). The expression of cell cycle checkpoint proteins and double strand break repair proteins was assayed by western blot analysis at 6 or 12 h post-IR.

p-mTOR(Ser2448) / mTOR / p-S6K(Thr389); 

PubMed: 25714019     


Phosphorylation of mTOR and p70S6K were detected by Western blot analysis 24 hours after treatment.

29344644 25714019
In vivo NU7441 intraperitoneally administrated at dose of 10 mg/kg maintains for at least 4 hours shows nontoxic and increases etoposide-induced tumor growth delay 2-fold in mice bearing SW620 xenografts. [2]

Protocol

Cell Research:

[2]

+ Expand
  • Cell lines: SW620, LoVo, V3-YAC and V3 cells
  • Concentrations: 0.5 μM or 1 μM
  • Incubation Time: 17 hours
  • Method:

    The effect of NU7441 on cellular survival following exposure to etoposide, doxorubicin, and ionizing radiation is measured in SW620, LoVo, V3, and V3-YAC cells by clonogenic assays. Briefly, growing cells in six-well plates or 6-cm dishes are exposed to etoposide or doxorubicin with or without NU7441 (0.5 or 1.0 μM) for 16 hours. For radiosensitization studies, NU7441 is added to the cells 1 hour before irradiation. V3 and V3-YAC cells are exposed to γ-irradiation (3.1 Gy/min 137Cesium). SW620 and LoVo are exposed to X-irradiation (2.9 Gy/min at 230 kV, 10 mA) due to the equipment available. After irradiation, the cells are incubated with or without NU7441 for a further 16 hours. Cells are then harvested by trypsinization, counted, and seeded into 10-cm diameter Petri dishes at densities varying from 100 to 105 per dish in drug-free medium for colony formation. Colonies are stained with crystal violet after 10 to 14 days and counted with an automated colony counter. The survival reduction factor (SRF) is calculated as the surviving fraction of cells in the absence of NU7441 divided by the surviving fraction of cells in the presence of NU7441 for any given dose or concentration of cytotoxic agent. The dose modification ratio (DMR90) is calculated as the concentration/dose of cytotoxic agent required to kill 90% of the cells in the absence of NU7441 divided by the concentration/dose of cytotoxic agent required to kill 90% of the cells in the presence of NU7441.


    (Only for Reference)
Animal Research:

[2]

+ Expand
  • Animal Models: Female rude mice bearing SW620 xenografts
  • Formulation: Sterile 0.9% sodium chloride solution
  • Dosages: 10 mg/kg
  • Administration: Intraperitoneally administrated
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 4 mg/mL warmed (9.67 mM)
Water Insoluble
Ethanol Insoluble
In vivo Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
5% DMSO+30% PEG 300+5% Tween 80+ddH2O
For best results, use promptly after mixing.
2mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 413.49
Formula

C25H19NO3S

CAS No. 503468-95-9
Storage powder
in solvent
Synonyms N/A

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field

Frequently Asked Questions

  • Question 1:

    Could you please suggest formulations of the drug for in vivo injection?

  • Answer:

    We tested the following formulation for in vivo use, 4% DMSO+30% PEG 300+5% Tween 80+ddH2O up to 1mg/mL. It is a clear solution.

  • Question 2:

    Previous aliquots were clear and colorless while this time, it becomes yellow when the powder was dissolved in DMSO? Could you advice on this?

  • Answer:

    Slight color variation due to different processing is normal and usually doesn't interfere with the function.

DNA-PK Signaling Pathway Map

DNA-PK Inhibitors with Unique Features

Related DNA-PK Products4

Tags: buy NU7441 (KU-57788) | NU7441 (KU-57788) supplier | purchase NU7441 (KU-57788) | NU7441 (KU-57788) cost | NU7441 (KU-57788) manufacturer | order NU7441 (KU-57788) | NU7441 (KU-57788) distributor
×
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID