NU7441 (KU-57788)

For research use only.

Catalog No.S2638

107 publications

NU7441 (KU-57788) Chemical Structure

Molecular Weight(MW): 413.49

NU7441 (KU-57788) is a highly potent and selective DNA-PK inhibitor with IC50 of 14 nM and also inhibits mTOR and PI3K with IC50 of 1.7 μM and 5 μM in cell-free assays, respectively. It reduces the frequency of NHEJ while increasing the rate of HDR following Cas9-mediated DNA cleavage.

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Selleck's NU7441 (KU-57788) has been cited by 107 publications

Purity & Quality Control

Choose Selective DNA-PK Inhibitors

Biological Activity

Description NU7441 (KU-57788) is a highly potent and selective DNA-PK inhibitor with IC50 of 14 nM and also inhibits mTOR and PI3K with IC50 of 1.7 μM and 5 μM in cell-free assays, respectively. It reduces the frequency of NHEJ while increasing the rate of HDR following Cas9-mediated DNA cleavage.
Targets
DNA-PK [1]
(Cell-free assay)
14 nM
In vitro

NU7441 increases the persistence of γH2AX foci after ionizing radiation–induced or etoposide-induced DNA damage. NU7441 (0.5 μM or 1 μM) appreciably increases G2-M accumulation induced by ionizing radiation, etoposide, and doxorubicin in both SW620 and LoVo cells. [2] NU7441 causes persistence of doxorubicin- and ionising radiation-induced DNA double-strand break and also slightly decreases homologous recombination activity DNA-PK-proficient M059-Fus-1 and DNA-PK-deficient M059 J human tumour cells. [3] NU7441 inhibits UV-induced RPA p34 hyperphosphorylation in a dose-dependent manner both in cells lacking and cells expressing polymerase η. [4] NU7441 increases levels of fludarabine-induced γH2AX foci and correspondingly decreased fludarabine-induced cell death in chronic lymphocytic leukemia cells. [5] NU7441 also inhibits mitoxantrone-induced DNA-PKcs autophosphorylation and repair in chronic lymphocytic leukemia cells. [6] It reduces the frequency of NHEJ while increasing the rate of HDR following Cas9-mediated DNA cleavage[7].

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
NCI-H1770 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXe4VHZxUUN3ME2wMlAzOTR|IN88US=> Mm[5V2FPT0WU
A172 NWrJeIxRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NULHSlJrUUN3ME2wMlE2OzF4IN88US=> MlTtV2FPT0WU
NCI-H526 NXPZXZRqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVTJR|UxRTBwMki0NFch|ryP NV\FN2VZW0GQR1XS
HDLM-2 M2nXb2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYrzcFA5UUN3ME2wMlMzOzR3IN88US=> M4LUOXNCVkeHUh?=
HuO-3N1 NX7mNIY{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmDwTWM2OD1yLkS2OlM3KM7:TR?= MlHVV2FPT0WU
NCI-SNU-1 Mlr5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFXI[4dKSzVyPUCuOlA6QTRizszN NXPmfmFtW0GQR1XS
SK-N-AS M{i3bmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlP3TWM2OD1yLk[yNlE3KM7:TR?= NUTHcHl5W0GQR1XS
LoVo NVj2Vnd6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3zo[2lEPTB;MD64Olc1QSEQvF2= MoDiV2FPT0WU
LAMA-84 NXHNW4Z[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoX0TWM2OD1yLkm4PFM{KM7:TR?= M1TObXNCVkeHUh?=
CTB-1 M4XrOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEfUWmRKSzVyPUGuNVE2PDZizszN MojZV2FPT0WU
KP-N-YS M2Hl[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXS4TGN5UUN3ME2xMlE1OjNzIN88US=> NWnOblJTW0GQR1XS
HH M{fQ[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3fQemlEPTB;MT6xPFA6OyEQvF2= MoXYV2FPT0WU
CHL-1 NGjGempIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVi4TIRCUUN3ME2xMlIyOzZ6IN88US=> M3fHRnNCVkeHUh?=
NB7 MlnsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{jWUWlEPTB;MT6yOFc1PSEQvF2= NVLsNnB2W0GQR1XS
HL-60 MknKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVHJR|UxRTFwM{ixPUDPxE1? NFzSRmJUSU6JRWK=
639-V MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF;1dYFKSzVyPUGuOFQyOjhizszN MVnTRW5ITVJ?
NCI-H1793 NWnGZnFIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmHrTWM2OD1zLkS1PFQh|ryP Mlr3V2FPT0WU
NEC8 NYnHcIYyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MorJTWM2OD1zLkW1N|Uh|ryP NWK2XJpQW0GQR1XS
PA-1 NVTXTYc6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGXiTpRKSzVyPUGuOVgzQTRizszN MoP6V2FPT0WU
D-423MG NED2VJRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHLuSZBKSzVyPUGuOlk{PjFizszN M2DWT3NCVkeHUh?=
NCI-H292 NEnIOXZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmrBTWM2OD1zLke0NFE{KM7:TR?= NV;MNXFNW0GQR1XS
SK-MEL-1 NGHFbXlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NW\1UnBSUUN3ME2xMlc6PDd7IN88US=> M32ycnNCVkeHUh?=
LB2241-RCC M3;hPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnToTWM2OD1{LkG0NVQ3KM7:TR?= MkHkV2FPT0WU
SK-MEL-3 MofnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkS3TWM2OD1{LkG2OFkh|ryP MUPTRW5ITVJ?
MHH-PREB-1 NXyxUoxyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mn3ITWM2OD1{LkG2OlA6KM7:TR?= NHi3[nNUSU6JRWK=
BFTC-905 NGrMbldIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mm\lTWM2OD1{LkG2Olg4KM7:TR?= M{X6N3NCVkeHUh?=
Ramos-2G6-4C10 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWLJR|UxRTJwMUm5NFkh|ryP M4LGenNCVkeHUh?=
G-361 NIj5SFBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEPYbZZKSzVyPUKuNlE3QCEQvF2= MoP3V2FPT0WU
MOLT-4 NUPyNldDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX;Yco9UUUN3ME2yMlIyQDh6IN88US=> NF;hNYVUSU6JRWK=
DEL NHXKbnlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGTWc5VKSzVyPUKuN|U2PjRizszN MmjHV2FPT0WU
MV-4-11 NFT0VoZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGLCSmpKSzVyPUKuN|c{QSEQvF2= M1THSHNCVkeHUh?=
SK-NEP-1 MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3TjTWlEPTB;Mj6zPFc5OyEQvF2= NXjZcZgyW0GQR1XS
RS4-11 M1e3Zmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlfoTWM2OD1{LkW2NFI{KM7:TR?= MXXTRW5ITVJ?
HuH-7 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGTpZ2pKSzVyPUKuOVY4ODJizszN MX3TRW5ITVJ?
A101D M3H5Xmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYLnV3lzUUN3ME2yMlYyOzN6IN88US=> MYDTRW5ITVJ?
KG-1 M37EcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEG1d4RKSzVyPUKuOlc6OjRizszN MUDTRW5ITVJ?
KALS-1 MmfIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4fkfWlEPTB;Mj62PVY{OyEQvF2= NXTzS2F5W0GQR1XS
VMRC-RCZ M1iyXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUjRVJVwUUN3ME2yMlc4OzJ6IN88US=> MUjTRW5ITVJ?
SK-UT-1 M3nOTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkPXTWM2OD1|LkG1N|Eh|ryP M3H5XXNCVkeHUh?=
SW962 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF;0[m9KSzVyPUOuNlA{PTJizszN NYrJRnBpW0GQR1XS
DBTRG-05MG NHq3bXlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{\rXmlEPTB;Mz6yPFA5PSEQvF2= Mo[xV2FPT0WU
PANC-08-13 NWXsSWNTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWfweFF5UUN3ME2zMlQyOjd6IN88US=> M3;NRXNCVkeHUh?=
QIMR-WIL Mn2yS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH;1VZVKSzVyPUOuOFE{PDFizszN NH:3UmtUSU6JRWK=
SK-MEL-30 Mlf0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGnxT3ZKSzVyPUOuOFI2QThizszN NGTxXllUSU6JRWK=
697 NVLib|JNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3zreGlEPTB;Mz60OFk6OyEQvF2= NIWxZ5NUSU6JRWK=
NY MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXrJR|UxRTNwNEWwNlIh|ryP NV\KbXRDW0GQR1XS
ES7 NH\BcWlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXeyXlloUUN3ME2zMlQ3PzJ7IN88US=> NImzU|JUSU6JRWK=
JVM-3 M2PjfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWrJR|UxRTNwNEiwO|ch|ryP NH;xXoJUSU6JRWK=
U031 NVfSXld7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUHJR|UxRTNwNUmzOlgh|ryP M3v1SXNCVkeHUh?=
BHT-101 NGOwXGRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXXJR|UxRTNwNUm5PFUh|ryP MnjPV2FPT0WU
8305C NUfoVmt3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYTWRpRmUUN3ME2zMlYyPzN4IN88US=> MYXTRW5ITVJ?
MG-63 NYrZNYdOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml;vTWM2OD1|Lk[yOlc3KM7:TR?= M4TGS3NCVkeHUh?=
NOS-1 MlLSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MULJR|UxRTNwNkWzNVIh|ryP Mn72V2FPT0WU
YH-13 M2\1Umdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml;FTWM2OD1|Lki3NVg6KM7:TR?= MlHzV2FPT0WU
LXF-289 NUnzRoxnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGW3N5ZKSzVyPUOuPVExPDFizszN NVnhbIc{W0GQR1XS
GOTO MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVHJR|UxRTNwOUG0PUDPxE1? M1rvfnNCVkeHUh?=
EKVX MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3LJ[mlEPTB;ND6yNlUzPCEQvF2= NFnQZWpUSU6JRWK=
CAL-51 NYTGRVBET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NITaXo1KSzVyPUSuNlQ5PTRizszN MlO0V2FPT0WU
AN3-CA Mle4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYnJR|UxRTRwMkW4NVMh|ryP MXjTRW5ITVJ?
IA-LM MnnUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWXYSXhFUUN3ME20MlI4QTN3IN88US=> NYXUNHJXW0GQR1XS
KU-19-19 M1:3Vmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXHJR|UxRTRwM{K5NlEh|ryP M1nh[HNCVkeHUh?=
A704 NYjRWXdIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWLJR|UxRTRwNEC4PFgh|ryP MkThV2FPT0WU
RH-18 Mmn3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoHiTWM2OD12LkS0PVU{KM7:TR?= MVHTRW5ITVJ?
IST-MEL1 NUHMR45rT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnT4TWM2OD12LkW4NlY{KM7:TR?= MUjTRW5ITVJ?
LU-134-A MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{\ZdGlEPTB;ND61PVY5PSEQvF2= NVvLdnFjW0GQR1XS
SF126 M{\CNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{fPNWlEPTB;ND62NFcyPSEQvF2= NEfnWnFUSU6JRWK=
EFO-27 NXPSWo8zT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3vGcWlEPTB;ND62OlUzPSEQvF2= MXnTRW5ITVJ?
SN12C NXTGTmJsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mm\yTWM2OD12LkexPFk5KM7:TR?= NHLJNFZUSU6JRWK=
L-363 NUf4ZpNvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYTJR|UxRTRwN{exNVYh|ryP M1nGeXNCVkeHUh?=
MEL-HO M1jFfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXPUfnZIUUN3ME20Mlc4QTh7IN88US=> NYGySmNjW0GQR1XS
TYK-nu MlTBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MULJR|UxRTRwOECxNlgh|ryP NXzKO283W0GQR1XS
MDA-MB-415 NVrnboJIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEewOGhKSzVyPUWuNFA{OTRizszN MkmwV2FPT0WU
HCC70 NWLJfHVjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4TX[2lEPTB;NT6wN|k{QSEQvF2= NITiNGVUSU6JRWK=
IGROV-1 NUf5UnE5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYDJR|UxRTVwMkWyPVIh|ryP MkjKV2FPT0WU
NCI-H1355 MlrvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXS1OXJ1UUN3ME21MlI6PiEQvF2= MlL1V2FPT0WU
23132-87 NFKxeFdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2rkd2lEPTB;NT6zNlAzPCEQvF2= NFrlc3VUSU6JRWK=
NB69 NFHa[HhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEeyUppKSzVyPUWuN|I1OiEQvF2= MnH1V2FPT0WU
HSC-2 NGHKPIdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkHETWM2OD13LkSxO|c{KM7:TR?= MWTTRW5ITVJ?
KYSE-410 NET4VnVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVnJR|UxRTVwNEe2N|Yh|ryP M{LWXXNCVkeHUh?=
GCIY M1vsZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NW\MfY56UUN3ME21MlUyOzd6IN88US=> MWTTRW5ITVJ?
A427 NEjNbY1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEniXmdKSzVyPUWuOVM3PjFizszN M1jyZXNCVkeHUh?=
ChaGo-K-1 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWjWOVVSUUN3ME21MlU3PTl7IN88US=> MofoV2FPT0WU
PFSK-1 M{Hr[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnLKTWM2OD13Lk[yNVk1KM7:TR?= NF;FdIJUSU6JRWK=
MLMA M1;ydGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEnkWHVKSzVyPUWuPFM3ODZizszN M4OyTHNCVkeHUh?=
RVH-421 NVXGV3JRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2LpeWlEPTB;Nj6wO|M{QCEQvF2= MX\TRW5ITVJ?
LB1047-RCC NYHjUW5WT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1zFZWlEPTB;Nj6xO|UzOiEQvF2= MoPyV2FPT0WU
MHH-NB-11 MkfzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHnWN|FKSzVyPU[uN|I4OjFizszN M4XITHNCVkeHUh?=
J-RT3-T3-5 NHza[W1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{m0UmlEPTB;Nj62N|I6OSEQvF2= MVXTRW5ITVJ?
UM-UC-3 M4\4NGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NW\1eWtuUUN3ME22MlY1OzN2IN88US=> Mm[wV2FPT0WU
IST-SL1 MnTDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUfCeXIxUUN3ME22MlY6OzZ7IN88US=> MV;TRW5ITVJ?
NB14 M3i1Xmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NH7BW5dKSzVyPU[uO|k4PjFizszN MYDTRW5ITVJ?
NBsusSR MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3vsNGlEPTB;Nj64NlUxOiEQvF2= M2TkZnNCVkeHUh?=
D-263MG M{e1[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4PGOmlEPTB;Nj65NVA3QCEQvF2= M3LvTnNCVkeHUh?=
NCI-H2347 NVT2XYVQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4[3RmlEPTB;Nj65N|IyOyEQvF2= M1fzbHNCVkeHUh?=
ES8 MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFPPVGJKSzVyPU[uPVc2QDhizszN NWXJcYVxW0GQR1XS
786-0 MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mnq2TWM2OD15LkC5O|g3KM7:TR?= NGXzZ3dUSU6JRWK=
EPLC-272H NFTl[|JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEfJTodKSzVyPUeuNVYzPDZizszN MVLTRW5ITVJ?
CAPAN-1 M2X0[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYjJR|UxRTdwMkSzOVkh|ryP M{fxeHNCVkeHUh?=
NCI-H82 Ml;PS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH\oOVFKSzVyPUeuNlY3PTlizszN NXPJe4kzW0GQR1XS
G-402 M3j3dGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGH6VXhKSzVyPUeuN|AxPTFizszN MWrTRW5ITVJ?
SW982 MoHpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF7RTHRKSzVyPUeuN|AzODNizszN MWjTRW5ITVJ?
OVCAR-4 Mnu3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGO0fnpKSzVyPUeuN|E{OjhizszN NFK2UZNUSU6JRWK=
KARPAS-299 NFO4bW9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mm\ITWM2OD15LkOyOlIzKM7:TR?= NULtOYJPW0GQR1XS
MIA-PaCa-2 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUnJR|UxRTdwM{[4NlMh|ryP NFHSS4NUSU6JRWK=
AU565 NFPTbIRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVnrO2VqUUN3ME23MlU6QDN|IN88US=> NETzZpFUSU6JRWK=
GAMG Ml\5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV\JR|UxRTdwNkSxN|Eh|ryP NXTDenVWW0GQR1XS
HuO9 Mn7vS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1njZWlEPTB;Nz63NVc1OyEQvF2= NUPRd25iW0GQR1XS
ACN NF\tVphIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXrwdYx1UUN3ME23Mlc1OzNizszN M3u3UXNCVkeHUh?=
RO82-W-1 NGfaT2ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV7yeGZ6UUN3ME23Mlc1PTN|IN88US=> NVjkSW1bW0GQR1XS
NKM-1 MkLJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWLteFFjUUN3ME23Mlc1QTV3IN88US=> MXvTRW5ITVJ?
CAL-12T NHzUUlFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MW\JR|UxRTdwOUSzOVIh|ryP NYLnc5ByW0GQR1XS
FADU MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV7JR|UxRThwMEO2OVQh|ryP MX\TRW5ITVJ?
NCI-H28 NYrnR3ZzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlHzTWM2OD16LkG2PVYzKM7:TR?= NV3wOZlWW0GQR1XS
LCLC-97TM1 NXztPIVCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoDtTWM2OD16LkKxNVIzKM7:TR?= NF7afo1USU6JRWK=
CHP-134 MmXYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWKwRVk4UUN3ME24MlI1OTh3IN88US=> MofXV2FPT0WU
HT-1080 M4nkV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3jMdGlEPTB;OD6yOVA6OyEQvF2= MkW3V2FPT0WU
PC-3 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYHHPXNXUUN3ME24MlI4Ozl{IN88US=> M2TGPXNCVkeHUh?=
SNU-449 NEn1XlRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn;UTWM2OD16LkK3PVMh|ryP MUHTRW5ITVJ?
VA-ES-BJ M{jUXGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{HKTWlEPTB;OD6zOFY5PiEQvF2= Mnf6V2FPT0WU
HT NI\UT3pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mlq1TWM2OD16LkO2OFkh|ryP NXni[VY5W0GQR1XS
HOS MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHXOd5JKSzVyPUiuN|c2QDlizszN MVfTRW5ITVJ?
KNS-62 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlraTWM2OD16LkO3O|YzKM7:TR?= NYL2VHFuW0GQR1XS
OAW-42 NF63OIhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXzSU3JMUUN3ME24Mlk2QTZ2IN88US=> NUDxd5NrW0GQR1XS
A549 NUXaNo1HT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYjJR|UxRTlwMEm2NVIh|ryP NV\BN2Z{W0GQR1XS
CAKI-1 MkDuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1TSeWlEPTB;OT6xOlYyKM7:TR?= MoLyV2FPT0WU
HCC1937 MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV\sXndQUUN3ME25MlY6QDZ3IN88US=> MmHCV2FPT0WU
GI-ME-N M4\uU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnHJTWM2OD17LkewNVM4KM7:TR?= NHmxT|BUSU6JRWK=
DU-4475 MnvDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIPvWXVKSzVyPUmuPVY6OzlizszN NXnUSVhDW0GQR1XS
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NCI-H1755 NWjRXnRrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmnHTWM2OD1zMD6yOFI5KM7:TR?= MXPTRW5ITVJ?
NCI-H1437 MkHDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXLJR|UxRTFyLkW3NlUh|ryP M{DkOXNCVkeHUh?=
VM-CUB-1 NGS1VmxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NILWe41KSzVyPUGwMlYyPjRizszN NFe1bXFUSU6JRWK=
A2058 NWPjeIxvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlyyTWM2OD1zMD62OFA1KM7:TR?= NWHPbo9qW0GQR1XS
BPH-1 M4fpfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVzSOnB6UUN3ME2xNE44OTR3IN88US=> Mm\tV2FPT0WU
NB5 NYj3[mRMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUjJR|UxRTFyLke1OVkh|ryP NUS4SY0zW0GQR1XS
G-401 NEjOdZhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYOxe41lUUN3ME2xNE44PjJ4IN88US=> NV;pS3Y5W0GQR1XS
CAL-72 M3Xa[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1nU[mlEPTB;MUCuPFA6PCEQvF2= MnSwV2FPT0WU
SK-MEL-28 Mo\OS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M13sW2lEPTB;MUCuPFIxOiEQvF2= NFrVPHhUSU6JRWK=
C32 MmKwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoXWTWM2OD1zMD64N|Q4KM7:TR?= NV\1NmJ4W0GQR1XS
NCI-H1155 MnvnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFP5WWtKSzVyPUGwMlg{PzZizszN M1q1NXNCVkeHUh?=
BB49-HNC NFm1fZVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVnJR|UxRTFyLki1PFYh|ryP MWfTRW5ITVJ?
GMS-10 MkTOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVrJR|UxRTFyLki5O|Eh|ryP NVPYdWVOW0GQR1XS
K5 M1vIfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkDLTWM2OD1zMD65NFcyKM7:TR?= M1jaVXNCVkeHUh?=
OS-RC-2 M2\PVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYDJR|UxRTFzLkC1OVkh|ryP MW\TRW5ITVJ?
HTC-C3 NV7HOpRnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkfQTWM2OD1zMT6wO|E1KM7:TR?= M1rBW3NCVkeHUh?=
LB996-RCC NFP0OlNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{G5WmlEPTB;MUGuNFczOyEQvF2= Mm\FV2FPT0WU
NCI-H1563 M2XacWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF7wPJRKSzVyPUGxMlExOTFizszN NUmxWpZ7W0GQR1XS
CAL-54 MoLzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWDIfm05UUN3ME2xNU41QDFzIN88US=> MWXTRW5ITVJ?
WM-115 MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXLTOYZsUUN3ME2xNU43QDJ2IN88US=> MoDDV2FPT0WU
COLO-684 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2LUfGlEPTB;MUGuO|I3PyEQvF2= NXSxT|c5W0GQR1XS
HOP-62 M1;Ue2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGjWS4VKSzVyPUGxMlc2ODhizszN NF\VTG5USU6JRWK=
NCI-H650 NYDmXFVGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH;IXlRKSzVyPUGxMlg6PjFizszN MX7TRW5ITVJ?
TE-11 MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4P0UGlEPTB;MUGuPVMyPSEQvF2= NGXlW5dUSU6JRWK=
COLO-679 NX;2b2FwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXnJR|UxRTFzLkm0OkDPxE1? MlPkV2FPT0WU
FTC-133 M2fLXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2nVemlEPTB;MUKuNFA4PiEQvF2= M3[yNnNCVkeHUh?=
D-283MED M1z5VWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2D2SGlEPTB;MUKuNFU3QSEQvF2= Mn3xV2FPT0WU
SK-PN-DW NF\ke2NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn\xTWM2OD1zMj6xPVAzKM7:TR?= NV3SSoZOW0GQR1XS
BALL-1 NYPJVYdIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmjETWM2OD1zMj6yOlYzKM7:TR?= MUPTRW5ITVJ?
GT3TKB MnyyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlW1TWM2OD1zMj6zNFc1KM7:TR?= M4PFZ3NCVkeHUh?=
HOP-92 MmrDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3nWPWlEPTB;MUKuOVI{OyEQvF2= MXHTRW5ITVJ?
M14 NUXBT5ZjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmTvTWM2OD1zMz6wN|M2KM7:TR?= MXzTRW5ITVJ?
SKG-IIIa M2W3fmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3fMOmlEPTB;MUOuNFU2PCEQvF2= MkXUV2FPT0WU
Becker M{K2WWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGi3enBKSzVyPUGzMlA2QCEQvF2= MYDTRW5ITVJ?
ES5 NYToUXBXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVTVdo5CUUN3ME2xN{4yOzV4IN88US=> M2H3W3NCVkeHUh?=
NCI-H2030 NUfQVoxIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1f6O2lEPTB;MUOuNlA3OiEQvF2= NVn6fVlvW0GQR1XS
SNU-423 Mk\ES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV7SeJZFUUN3ME2xN{4{QDFizszN MnnNV2FPT0WU
CP50-MEL-B M4DZN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MonWTWM2OD1zMz62NlMzKM7:TR?= M2XGUHNCVkeHUh?=
NCI-H1092 NHH6bZhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkHPTWM2OD1zMz63OFc2KM7:TR?= Mmm5V2FPT0WU
8-MG-BA MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkfoTWM2OD1zMz63OVE{KM7:TR?= M4roXHNCVkeHUh?=
CAL-27 NFzTVHpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4f6RmlEPTB;MUSuNFczPyEQvF2= NHzGUpZUSU6JRWK=
AGS MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2i2emlEPTB;MUSuNVMyQSEQvF2= MX3TRW5ITVJ?
MZ2-MEL M1;0VGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUTJR|UxRTF2LkG0PFgh|ryP M4PZPXNCVkeHUh?=
BFTC-909 MnrSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX\kTZdVUUN3ME2xOE42ODV3IN88US=> MUHTRW5ITVJ?
D-566MG MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX;JR|UxRTF2Lke3NFYh|ryP NV3jS4RoW0GQR1XS
MZ7-mel MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUjJZ4ljUUN3ME2xOU4yODZ5IN88US=> MkPEV2FPT0WU
TE-5 NUDTeHM3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUjuTGh{UUN3ME2xOU4zOzN|IN88US=> MnzuV2FPT0WU
647-V M1;SfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEjYUoRKSzVyPUG1MlI4ODVizszN NILuU2pUSU6JRWK=
DMS-114 M3HzW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXr6b|QyUUN3ME2xOU4{OjlzIN88US=> M33B[3NCVkeHUh?=
ME-180 MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M37weGlEPTB;MUWuOFc5OyEQvF2= NUXDOGhXW0GQR1XS
MS-1 MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVrJR|UxRTF3LkW2NlMh|ryP MmnZV2FPT0WU
NUGC-3 M4PBXGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX7JR|UxRTF3Lk[yOFUh|ryP NHXIOXJUSU6JRWK=
GB-1 MoPOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYLiNnZ2UUN3ME2xOU43PDN5IN88US=> MnnvV2FPT0WU
LOXIMVI MmrxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{HyRmlEPTB;MUWuPFkyQSEQvF2= NELielhUSU6JRWK=
NCI-H1304 MofmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIXNUVRKSzVyPUG1Mlg6OjhizszN M{f1bXNCVkeHUh?=
KURAMOCHI NH\iVYxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH;0XFVKSzVyPUG1Mlk4OSEQvF2= M2TDdXNCVkeHUh?=
SW1783 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHTiOppKSzVyPUG2MlA6QTNizszN NUnPOI9rW0GQR1XS
EGI-1 M3PYbGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnH1TWM2OD1zNj61N|Y2KM7:TR?= MlzaV2FPT0WU
KGN NFS4bmxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYPVWGVYUUN3ME2xOk42PTh4IN88US=> NV20PWVDW0GQR1XS
PANC-03-27 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVLJR|UxRTF4Lke2OlIh|ryP M{[0eXNCVkeHUh?=
RH-1 MmfvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NU\tenprUUN3ME2xOk45OjVizszN NFHNNppUSU6JRWK=
HT-1376 M3XOTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWXJR|UxRTF4Lki0OFYh|ryP NXHGZYM5W0GQR1XS
ZR-75-30 M3vTfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFj4UIhKSzVyPUG2Mlk{PjFizszN NXHZUJJvW0GQR1XS
TI-73 M4LIXGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{TCXWlEPTB;MU[uPVQxQCEQvF2= MUPTRW5ITVJ?
TK10 M1L4eGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVvJR|UxRTF5LkCwO|kh|ryP MXLTRW5ITVJ?
SW684 NUKzXpc2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHzhXGtKSzVyPUG3MlAyPTRizszN NUPxeI17W0GQR1XS
RPMI-8866 M3LFdmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUHJR|UxRTF5LkC2PVkh|ryP NUfh[ohJW0GQR1XS
LNCaP-Clone-FGC NWHENWhZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVrJR|UxRTF5LkWyNFEh|ryP NIO4R2JUSU6JRWK=
NCI-H2291 MnfiS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFfnNnFKSzVyPUG4MlQ{PDVizszN NFjhXmFUSU6JRWK=
T47D NIrMSlVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHGyVnZKSzVyPUG4MlQ5QCEQvF2= NV\QSnI1W0GQR1XS
A204 M3faTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlnYTWM2OD1zOD61OFUzKM7:TR?= MkTEV2FPT0WU
HT-144 MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFvZfpdKSzVyPUG4Mlc1OjdizszN NVv3OHlPW0GQR1XS
MDA-MB-361 M3O5R2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFHKbWtKSzVyPUG5MlA4OTRizszN NXXwUVFRW0GQR1XS
HCC1806 MorlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoXqTWM2OD1zOT6xOVkyKM7:TR?= NUXvXZNLW0GQR1XS
NCI-H596 M4rCWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmTFTWM2OD1zOT62N|kyKM7:TR?= NFG5ZXpUSU6JRWK=
K-562 M2LLbWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVTUcJBnUUN3ME2xPU45QTJ4IN88US=> MV7TRW5ITVJ?
D-336MG MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGi2SHhKSzVyPUG5Mlk{OjJizszN NEPyZphUSU6JRWK=
SK-MEL-2 M{P2Rmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWnmOol3UUN3ME2yNE4yPTV7IN88US=> NVT3SGlFW0GQR1XS
HEC-1 NUXYOmROT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{Hv[WlEPTB;MkCuOFk4QCEQvF2= MVjTRW5ITVJ?
EW-13 NF\WZppIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Ml7iTWM2OD1{MD61OFQ{KM7:TR?= MWrTRW5ITVJ?
Hs-578-T NUTQNYpQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHzMXJZKSzVyPUKwMlU2QDNizszN MmnBV2FPT0WU
SJSA-1 M{K0UWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Moq0TWM2OD1{MD61Olg5KM7:TR?= NHHFOGJUSU6JRWK=
RCC10RGB MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmfBTWM2OD1{MD62O|E6KM7:TR?= M3\zc3NCVkeHUh?=
LAN-6 M4S3SWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmHtTWM2OD1{MT6wN|k3KM7:TR?= NEL1dJFUSU6JRWK=
NCI-H1048 MnSxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFTtfIlKSzVyPUKxMlIzPThizszN M362TXNCVkeHUh?=
CW-2 NVy3RpNzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGLlRoNKSzVyPUKxMlI4ODVizszN MnPGV2FPT0WU
HCC2157 Mn3oS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV\JR|UxRTJzLkO2JO69VQ>? MWrTRW5ITVJ?
EW-22 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYjJR|UxRTJzLkO3OkDPxE1? M2LWXnNCVkeHUh?=
A253 NFPWSVlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEHsVnlKSzVyPUKxMlQ1QDFizszN MnXqV2FPT0WU
BE-13 M1nwPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3i1WGlEPTB;MkGuOlEyOyEQvF2= MVLTRW5ITVJ?
KINGS-1 NFnkXHVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUG4dIt[UUN3ME2yNU43OzF4IN88US=> NYPZOXBMW0GQR1XS
ETK-1 NXTlOmhjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2LscGlEPTB;MkGuPFE2OiEQvF2= NYjkVFh5W0GQR1XS
NCI-H2452 M3nKXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWjUVXZ2UUN3ME2yNU45PjR5IN88US=> M{XaTXNCVkeHUh?=
HPAF-II NYnYbpg4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYj2V5BuUUN3ME2yNU45QTJ|IN88US=> NYTZOVRoW0GQR1XS
D-542MG NUXTcpZUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWDJR|UxRTJzLkmwOlkh|ryP NGWydHlUSU6JRWK=
NCI-H630 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWPJR|UxRTJ{LkCyPVYh|ryP NHPMfldUSU6JRWK=
TGBC11TKB M1\vNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlL2TWM2OD1{Mj6wOFkh|ryP NIHsZVdUSU6JRWK=
BCPAP NIH1PFZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVjJR|UxRTJ{Lk[xNUDPxE1? NYnuV3pvW0GQR1XS
HLE MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYfJR|UxRTJ{Lk[5O{DPxE1? MUjTRW5ITVJ?
NCI-H727 NI[ye2lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3vZXWlEPTB;MkKuO|M2KM7:TR?= MWTTRW5ITVJ?
RD NYXlSWhUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4OzcGlEPTB;MkKuO|UyQCEQvF2= MYjTRW5ITVJ?
NCI-H522 NH3lbVNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NF:xPVBKSzVyPUKyMlg1OzFizszN Ml7RV2FPT0WU
CGTH-W-1 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NH23bmRKSzVyPUKzMlA3PDFizszN NGfi[3FUSU6JRWK=
SK-LU-1 NEH3b21Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV;JR|UxRTJ|LkS2PFMh|ryP MVjTRW5ITVJ?
BB65-RCC NYXCV4ZLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUjJR|UxRTJ|Lke4OlMh|ryP M4XHPXNCVkeHUh?=
HSC-3 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1\ofGlEPTB;MkOuPFUzPyEQvF2= MWjTRW5ITVJ?
SK-MES-1 M{nteWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWnJR|UxRTJ2LkCxOlEh|ryP MWDTRW5ITVJ?
DB M2rEPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1uzUmlEPTB;MkSuNVAzQCEQvF2= MWLTRW5ITVJ?
HO-1-N-1 Mo\FS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUfJR|UxRTJ2LkOwPVMh|ryP M3zr[XNCVkeHUh?=
MKN1 M2WxdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUTJR|UxRTJ2Lk[4JO69VQ>? M4P6e3NCVkeHUh?=
MN-60 Mn;JS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVPJR|UxRTJ2Lki1NVkh|ryP NF7WdYxUSU6JRWK=
8505C MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NW\DSZBqUUN3ME2yOU4yQDR3IN88US=> Moi0V2FPT0WU
COLO-320-HSR MmfYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUTJR|UxRTJ3LkKyNFgh|ryP M2rqOHNCVkeHUh?=
BB30-HNC MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWLhfZduUUN3ME2yOU4zPDh|IN88US=> Mn;nV2FPT0WU
KM12 NHnxb3dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MULJR|UxRTJ3LkW4NFch|ryP M4\yZXNCVkeHUh?=
NB13 NFHlSYZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYPJR|UxRTJ3LkW4PVgh|ryP MXjTRW5ITVJ?
HCC2998 M2nHV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGfKVXFKSzVyPUK2MlAzQDNizszN Mnz1V2FPT0WU
U-118-MG MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXXJR|UxRTJ4LkC4NFgh|ryP MUfTRW5ITVJ?
NB10 NGrD[GhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M13pXGlEPTB;Mk[uNlM1KM7:TR?= NVvqeYpOW0GQR1XS
SK-LMS-1 NF32SnhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVTKUYp7UUN3ME2yO{4xPzB2IN88US=> NUTYPIp2W0GQR1XS
SW1573 M1;Bbmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIHVXm5KSzVyPUK3MlEyKM7:TR?= Ml6yV2FPT0WU
LB373-MEL-D M4XlTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUfZbGJDUUN3ME2yO{4yOjl2IN88US=> MkPwV2FPT0WU
DK-MG M2fMUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MofJTWM2OD1{Nz6xPFE4KM7:TR?= M4HNVXNCVkeHUh?=
RMG-I MlXuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{fTXWlEPTB;MkeuNlAzQSEQvF2= MlvqV2FPT0WU
SW1088 NXXOfXZjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4fwO2lEPTB;MkeuOVA1OiEQvF2= MX3TRW5ITVJ?
SK-OV-3 NFuzfFFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUDJR|UxRTJ5Lke1PVMh|ryP NXjoXVZIW0GQR1XS
KP-N-YN MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIrHTXBKSzVyPUK3MlgxPDNizszN MVPTRW5ITVJ?
RPMI-7951 M1zHZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXXYc2lMUUN3ME2yPE4zPDV4IN88US=> M3PnXnNCVkeHUh?=
CaR-1 M1K4PWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYfJR|UxRTJ6LkW1PFIh|ryP MUnTRW5ITVJ?
MKN7 M4T4WGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2LwUmlEPTB;MkiuOVk3PCEQvF2= MXTTRW5ITVJ?
CHP-212 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWrJR|UxRTJ6Lke0NFEh|ryP MV3TRW5ITVJ?
KYSE-450 MnvwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVnpSJBsUUN3ME2yPE45ODlzIN88US=> MVfTRW5ITVJ?
RXF393 MoXlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVPJR|UxRTJ7LkK5NFYh|ryP NXWwS4oyW0GQR1XS
P30-OHK NFe0UZJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEHDO3BKSzVyPUK5MlMxPDhizszN NYrhOpRtW0GQR1XS
Ca9-22 NHvSNVBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUjJR|UxRTJ7LkSyPVkh|ryP NHn3cZZUSU6JRWK=
RT-112 NFroUnFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH\XfZZKSzVyPUK5MlQ3OTFizszN MXHTRW5ITVJ?
ES1 NIj3[5VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkPSTWM2OD1{OT64OVQ1KM7:TR?= NXHWeJE3W0GQR1XS
HCE-4 M1XTPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn70TWM2OD1{OT64O|g3KM7:TR?= M{L3XnNCVkeHUh?=
AM-38 Mn[zS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUnJR|UxRTNyLkC2NFYh|ryP Mle4V2FPT0WU
AsPC-1 NX7lbI5rT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXzJR|UxRTNyLkiwOVMh|ryP NYTVWYxyW0GQR1XS
TE-9 M{PYV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFTxVmJKSzVyPUOwMlg4OzdizszN M1vkXHNCVkeHUh?=
HuP-T4 MnjrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkP6TWM2OD1|MD65OlM5KM7:TR?= M4nxXXNCVkeHUh?=
LB2518-MEL MlHlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2\mXGlEPTB;M{GuNFc1PCEQvF2= NV24SHFoW0GQR1XS
NCI-H1703 M1;k[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2n6V2lEPTB;M{GuNFkxPSEQvF2= NIXOTXdUSU6JRWK=
NCI-H2228 MlHxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXTJR|UxRTNzLkS2OVEh|ryP NWfkW5oxW0GQR1XS
SCC-4 NWi4bYN1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUKzVotUUUN3ME2zNU46OThzIN88US=> MWPTRW5ITVJ?
KNS-81-FD MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYfJR|UxRTN{LkCxNlgh|ryP NWjOUYhjW0GQR1XS
NTERA-S-cl-D1 NVvHPXh3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV:3U4RkUUN3ME2zNk4xPzN7IN88US=> NHzqRo1USU6JRWK=
Daoy NEficGJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVWy[ld6UUN3ME2zNk4xQDN6IN88US=> MXTTRW5ITVJ?
ES4 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3:1R2lEPTB;M{KuN|kzOiEQvF2= MXLTRW5ITVJ?
MHH-ES-1 MkLkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NED2dJJKSzVyPUOyMlQ5PzJizszN MV3TRW5ITVJ?
C-33-A NInM[5JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWH2[5ZXUUN3ME2zNk44PzJ6IN88US=> M{DoOHNCVkeHUh?=
BHY NUHofY9WT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2rremlEPTB;M{KuPVQ6PSEQvF2= MmLNV2FPT0WU
Detroit562 NWjoW5RXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXTJR|UxRTN|Lk[2OVch|ryP NF7CWlNUSU6JRWK=
EW-1 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVHQWlUzUUN3ME2zN{46OzJ{IN88US=> M4X0OHNCVkeHUh?=
NCI-H1395 NHH6UIhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3PFNGlEPTB;M{SuNFc6QSEQvF2= M3Hnb3NCVkeHUh?=
KM-H2 M3faTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NH\NfXNKSzVyPUO2MlQ4PDNizszN NY\K[HA4W0GQR1XS
NCI-H520 NX3kcpBbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mo\zTWM2OD1|Nj63OVQyKM7:TR?= MYnTRW5ITVJ?
D-392MG MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIjyPG1KSzVyPUO3MlM{PDRizszN M1jLRnNCVkeHUh?=
NOMO-1 NX7vflBKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1fvc2lEPTB;M{euPFA5QSEQvF2= MWrTRW5ITVJ?
TE-6 NYTsTGVmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1vSZWlEPTB;M{iuNVI1KM7:TR?= M4jYNnNCVkeHUh?=
HT-3 NYLjOmJST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXLrXVJRUUN3ME2zPE41PDN4IN88US=> M4fIcnNCVkeHUh?=
RPMI-8226 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUTBUlZoUUN3ME2zPE46PTF7IN88US=> Mme4V2FPT0WU
U251 MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF7XZ4xKSzVyPUO5MlAyOjRizszN MnrjV2FPT0WU
GCT MnHUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4riPGlEPTB;M{muNVg2OiEQvF2= NEnI[VVUSU6JRWK=
A431 NIDWd5BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVLJR|UxRTN7LkG4PVQh|ryP NUXHWIl[W0GQR1XS
TE-12 M3LncWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoP6TWM2OD1|OT6yOFQ5KM7:TR?= MlK0V2FPT0WU
HMV-II NWjINXpwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoD3TWM2OD1|OT61NFQ4KM7:TR?= MYHTRW5ITVJ?
IST-MES1 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHPZVoVKSzVyPUSwMlE2ODJizszN MonFV2FPT0WU
SW13 NV65N|BnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWjJR|UxRTRyLkWxPUDPxE1? NIrNOJpUSU6JRWK=
SF295 MlfDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUDvXIxKUUN3ME20NE45ODZ4IN88US=> NGC0fodUSU6JRWK=
MDA-MB-157 M3TXUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3TMS2lEPTB;NECuPVQ3OiEQvF2= M1nEe3NCVkeHUh?=
TE-1 NYfkdZRIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHPEcpFKSzVyPUSxMlg4OTRizszN NVzWNGk2W0GQR1XS
HuCCT1 NUDyVVNpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnjjTWM2OD12Mj61Nlg6KM7:TR?= MV\TRW5ITVJ?
KYSE-510 NGfUboZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4DBNmlEPTB;NEOuNVc2PCEQvF2= M3v2XXNCVkeHUh?=
NCI-H358 MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkKzTWM2OD12ND6wN|A1KM7:TR?= NWLqb4RyW0GQR1XS
SW900 MnjNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXTJR|UxRTR2LkC3OVgh|ryP NEPvOpVUSU6JRWK=
CAS-1 NULjWnhYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGfkS|hKSzVyPUS0MlA6QTFizszN NHTYXIVUSU6JRWK=
TE-8 NXrjeJM6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmrZTWM2OD12ND61OlU5KM7:TR?= MlLhV2FPT0WU
P12-ICHIKAWA NELifIZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2XOXGlEPTB;NESuOlEyOiEQvF2= NYTGVpBPW0GQR1XS
YKG-1 Ml63S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3jJfmlEPTB;NESuO|gyKM7:TR?= M4XxTXNCVkeHUh?=
SNU-C2B NU\kNJJ5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVvJR|UxRTR2Lke5NFMh|ryP MUDTRW5ITVJ?
LCLC-103H M{j5UGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn:zTWM2OD12ND64O|A{KM7:TR?= MWjTRW5ITVJ?
U-87-MG NHvqS|NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MU\JR|UxRTR3LkGwNlIh|ryP NXvFRXAzW0GQR1XS
HAL-01 MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXLJR|UxRTR3LkGzO|kh|ryP M4DST3NCVkeHUh?=
OVCAR-8 NGi2[JRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2DNd2lEPTB;NEWuN|U3PCEQvF2= NEXySYxUSU6JRWK=
KYSE-150 NV\TeFBmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFPoUnVKSzVyPUS3MlExPTJizszN NFzYNHJUSU6JRWK=
OE33 NEnkSJRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFrPR|lKSzVyPUS3MlE1OjlizszN M2C1SXNCVkeHUh?=
CAL-62 NYHneoN2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWfJR|UxRTR5LkSwOlgh|ryP NYnH[|BPW0GQR1XS
TCCSUP M1;WVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mo\pTWM2OD12Nz62NlY1KM7:TR?= NWKySmQxW0GQR1XS
H4 NGnidpVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFXnRm5KSzVyPUS3MlY3OjFizszN M1XjbnNCVkeHUh?=
CP66-MEL MnjlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoPoTWM2OD12OD6wO|A1KM7:TR?= NYHBUopWW0GQR1XS
SNB75 M2frN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYXJR|UxRTR6LkG4O|Qh|ryP NIrXNm1USU6JRWK=
Mo-T MkD1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV3JR|UxRTR6LkK3PUDPxE1? MnXaV2FPT0WU
BT-549 MkLBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWPJR|UxRTR6LkO3Nlkh|ryP MmL0V2FPT0WU
IGR-1 NVHBc5puT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlTJTWM2OD12OD62OlQ2KM7:TR?= NH7tVZpUSU6JRWK=
NCI-H1299 NHnpWFNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVfJR|UxRTR6LkeyOFgh|ryP MVPTRW5ITVJ?
ALL-PO NV3KeIQ4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnHOTWM2OD12OT65NlY5KM7:TR?= MYLTRW5ITVJ?

... Click to View More Cell Line Experimental Data

Assay
Methods Test Index PMID
Western blot
p-DNA-PKcs / DNA-PKcs / p-ATM / ATM / p-ATR / ATR / Ku70 / p-CHK1 / p-CHK2/ p-AKT / RAD51; 

PubMed: 29344644     


SUNE1 cells were irradiated with 5 Gy in the presence or absence of NU7441 (2 µM). The expression of cell cycle checkpoint proteins and double strand break repair proteins was assayed by western blot analysis at 6 or 12 h post-IR.

p-mTOR(Ser2448) / mTOR / p-S6K(Thr389); 

PubMed: 25714019     


Phosphorylation of mTOR and p70S6K were detected by Western blot analysis 24 hours after treatment.

29344644 25714019
In vivo NU7441 intraperitoneally administrated at dose of 10 mg/kg maintains for at least 4 hours shows nontoxic and increases etoposide-induced tumor growth delay 2-fold in mice bearing SW620 xenografts. [2]

Protocol

Cell Research:

[2]

- Collapse
  • Cell lines: SW620, LoVo, V3-YAC and V3 cells
  • Concentrations: 0.5 μM or 1 μM
  • Incubation Time: 17 hours
  • Method:

    The effect of NU7441 on cellular survival following exposure to etoposide, doxorubicin, and ionizing radiation is measured in SW620, LoVo, V3, and V3-YAC cells by clonogenic assays. Briefly, growing cells in six-well plates or 6-cm dishes are exposed to etoposide or doxorubicin with or without NU7441 (0.5 or 1.0 μM) for 16 hours. For radiosensitization studies, NU7441 is added to the cells 1 hour before irradiation. V3 and V3-YAC cells are exposed to γ-irradiation (3.1 Gy/min 137Cesium). SW620 and LoVo are exposed to X-irradiation (2.9 Gy/min at 230 kV, 10 mA) due to the equipment available. After irradiation, the cells are incubated with or without NU7441 for a further 16 hours. Cells are then harvested by trypsinization, counted, and seeded into 10-cm diameter Petri dishes at densities varying from 100 to 105 per dish in drug-free medium for colony formation. Colonies are stained with crystal violet after 10 to 14 days and counted with an automated colony counter. The survival reduction factor (SRF) is calculated as the surviving fraction of cells in the absence of NU7441 divided by the surviving fraction of cells in the presence of NU7441 for any given dose or concentration of cytotoxic agent. The dose modification ratio (DMR90) is calculated as the concentration/dose of cytotoxic agent required to kill 90% of the cells in the absence of NU7441 divided by the concentration/dose of cytotoxic agent required to kill 90% of the cells in the presence of NU7441.


    (Only for Reference)
Animal Research:

[2]

- Collapse
  • Animal Models: Female rude mice bearing SW620 xenografts
  • Dosages: 10 mg/kg
  • Administration: Intraperitoneally administrated
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 4 mg/mL warmed (9.67 mM)
Water Insoluble
Ethanol Insoluble
In vivo Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
5% DMSO+30% PEG 300+5% Tween 80+ddH2O
For best results, use promptly after mixing.
2mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 413.49
Formula

C25H19NO3S

CAS No. 503468-95-9
Storage powder
in solvent
Synonyms N/A
Smiles O=C1C=C(OC2=C1C=CC=C2C3=CC=CC4=C3SC5=C4C=CC=C5)N6CCOCC6

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Dosage mg/kg Average weight of animals g Dosing volume per animal ul Number of animals
Step 2: Enter the in vivo formulation ()
% DMSO % % Tween 80 % ddH2O
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Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

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Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

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This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field

Frequently Asked Questions

  • Question 1:

    Could you please suggest formulations of the drug for in vivo injection?

  • Answer:

    We tested the following formulation for in vivo use, 4% DMSO+30% PEG 300+5% Tween 80+ddH2O up to 1mg/mL. It is a clear solution.

  • Question 2:

    Previous aliquots were clear and colorless while this time, it becomes yellow when the powder was dissolved in DMSO? Could you advice on this?

  • Answer:

    Slight color variation due to different processing is normal and usually doesn't interfere with the function.

DNA-PK Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID