CAS No. 3414-63-9

Batch: Purity:99.55
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Norepinephrine tartrate Chemical Structure
Chemical Structure
Check the Norepinephrine tartrate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 4-(2-amino-1-hydroxyethyl)benzene-1,2-diol;(2R,3R)-2,3-dihydroxybutanedioate
CAS Number 3414-63-9
Molecular Formula

C8H11NO3.C4H6O6
Molecular Weight (MW) 319.27
InChIKey WNPNNLQNNJQYFA-LREBCSMRSA-L

Ordering Information

Biological Activity

Norepinephrine tartrate is a sympathomimetic amine and potent agonist of adrenergic receptors, specifically targeting α1, α2, and β1 adrenoceptors. Activation of α1 receptors stimulates phospholipase C via Gq proteins to induce smooth muscle contraction, while α2 receptor signaling suppresses adenylyl cyclase via Gi proteins to lower cAMP levels. Furthermore, β1 receptor stimulation activates the Gs-adenylyl cyclase-cAMP-protein kinase A cascade to increase cardiac contractility. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
1 mg 5 mg 10 mg
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 64 mg/mL (200.45 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 64 mg/mL
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.