Home Immunology & Inflammation TNF-alpha inhibitor - Interleukins inhibitor - Caspase inhibitor - NF-κB inhibitor - ERK inhibitor - JNK inhibitor - p38 MAPK inhibitor Mulberroside A

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Mulberroside A TNF-alpha inhibitor

Mulberroside A, isolated from the ethanol extract of Morus alba roots, is widely employed as an active ingredient in cosmetic products due to its anti-tyrosinase and anti-oxidant activities. This compound decreases the expressions of TNF-α, IL-1β and IL-6 and inhibits the activation of NALP3, caspase-1 and NF-κB and the phosphorylation of ERK, JNK and p38.

Mulberroside A TNF-alpha inhibitor Chemical Structure

Chemical Structure

Molecular Weight: 568.52

Purity & Quality Control

Related Products

Signaling Pathway

TNF-alpha Signaling Pathways

TNF-alpha Signaling Pathway

Mechanism of Action

Targets
TNF-α [1] IL-1β [1] IL-6 [1] NALP3 [1] Caspase-1 [1] Click to View More Targets

In vitro
In vitro
但其中“Mulberroside A”重复出现了很多次。我希望只保留它第一次出现的地方，其他出现的地方改为用代词或类似this compound/this chemical（需要注意这个东西是不是chemical）的词替换，注意保持语义语法正确。一般来说，紧跟在this compound后面的小括号内的词是它的别名，也需要整个替换掉。其他地方不要修改。只返回给我修改后的段落，不加任何话语。

In Vivo
In vivo
但其中“Mulberroside A”重复出现了很多次。我希望只保留它第一次出现的地方，其他出现的地方改为用代词或类似this compound/this chemical（需要注意这个东西是不是chemical）的词替换，注意保持语义语法正确。一般来说，紧跟在this compound后面的小括号内的词是它的别名，也需要整个替换掉。其他地方不要修改。只返回给我修改后的段落，不加任何话语。

References
  • https://pubmed.ncbi.nlm.nih.gov/24687774/

Chemical Information

Molecular Weight 568.52 Formula

C26H32O14
CAS No. 102841-42-9 SDF --
Synonyms N/A
Smiles C1=CC(=C(C=C1OC2C(C(C(C(O2)CO)O)O)O)O)C=CC3=CC(=CC(=C3)OC4C(C(C(C(O4)CO)O)O)O)O

Storage and Stability

Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 10 mg/mL ( (17.58 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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