Home Apoptosis Bcl-2 modulator MBoIN179

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MBoIN179 Bcl-2 modulator

Cat.No.E6887

MBoIN179 is a small-molecule modulator that disrupts the transmembrane-domain interaction between the anti-apoptotic protein MCL1 and the pro-apoptotic protein BOK. By releasing BOK from MCL1-mediated sequestration, MBoIN179 promotes BOK-dependent oligomerization and mitochondrial outer-membrane permeabilization, thereby inducing apoptotic cell death.
MBoIN179 Bcl-2 modulator Chemical Structure

Chemical Structure

Molecular Weight: 352.50

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Chemical Information, Storage & Stability

Molecular Weight 352.50 Formula

C20H24N4S

 Storage (From the date of receipt) 3 years-20°C(in the dark) powder
CAS No. 379246-60-3 Download SDF Storage of Stock Solutions Solutions are unstable. Prepare fresh or purchase small, pre-packaged sizes. Repackage upon receipt.

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