Dimercaprol

Catalog No.S4446 Synonyms: Bal, 2,3-Dimercapto-1-propanol, Dithioglycerol

For research use only.

Dimercaprol (Bal, 2,3-Dimercapto-1-propanol, Dithioglycerol) is an acrolein scavenger that inhibits HIV-1 tat activity, viral production, and infectivity in vitro.

Dimercaprol Chemical Structure

CAS No. 59-52-9

Purity & Quality Control

Choose Selective HIV Inhibitors

Biological Activity

Description Dimercaprol (Bal, 2,3-Dimercapto-1-propanol, Dithioglycerol) is an acrolein scavenger that inhibits HIV-1 tat activity, viral production, and infectivity in vitro.
Targets
HIV-1 tat [1]

Protocol (from reference)

Chemical Information

Molecular Weight 124.22
Formula

C3H8OS2

Density 1.239 g/mL
CAS No. 59-52-9
Storage 2 years -20°C liquid

In vivo Formulation Calculator (Clear solution)

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT05372731 Not yet recruiting Other: Recruitment Maneuver Acute Respiratory Distress Syndrome Southeast University China June 1 2022 Not Applicable
NCT05075161 Recruiting Drug: Pirfenidone|Drug: Placebo Acute Respiratory Distress Syndrome (ARDS) Università Vita-Salute San Raffaele June 2022 Phase 3
NCT05469022 Recruiting Drug: Neoadjuvant lazertinib Non Small Cell Lung Cancer Konkuk University Medical Center|Yuhan Corporation May 19 2022 Phase 2
NCT05317507 Recruiting Drug: CBD oil|Drug: Placebo Healthy Adults Canopy Growth Corporation|Auburn University May 9 2022 Phase 1
NCT05445258 Recruiting Device: InnoCath AB® hyper-compliant balloon catheter Lesions in the Superficial Femoral Artery and/or Popliteal Artery Pars I/II InnoRa GmbH May 25 2022 Not Applicable

(data from https://clinicaltrials.gov, updated on 2022-08-01)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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