Home Microbiology HIV inhibitor Zingibroside R1 For research use only.

Zingibroside R1

Zingibroside R1, isolated from rhizomes of Panax zingiberensis Wu et Feng (Araliaceae), has some anti-HIV-1 activity. Zingibroside R1 shows the inhibitory effects on the 2-deoxy-D-glucose (2-DG) uptake by EAT cells with IC50 of 91.3 µM and the growth of MT-4 cells with CC50 of 46.2 µM.

Zingibroside R1 Chemical Structure

Zingibroside R1 Chemical Structure

CAS: 80930-74-1

Purity & Quality Control

Batch: S095801 DMSO] 100 mg/mL] false] ] ] false] ] ] false Purity: 99.88%
99.88

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Biological Activity

Description Zingibroside R1, isolated from rhizomes of Panax zingiberensis Wu et Feng (Araliaceae), has some anti-HIV-1 activity. Zingibroside R1 shows the inhibitory effects on the 2-deoxy-D-glucose (2-DG) uptake by EAT cells with IC50 of 91.3 µM and the growth of MT-4 cells with CC50 of 46.2 µM.
Targets
HIV-1 [1] 2-DG [1]
(in EAT cells)
91.3 μM

Chemical Information & Solubility

Molecular Weight 794.97 Formula

C42H66O14
CAS No. 80930-74-1 SDF --
Smiles CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)OC6C(C(C(C(O6)C(=O)O)O)O)OC7C(C(C(C(O7)CO)O)O)O)C)C)C2C1)C)C(=O)O)C
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 100 mg/mL ( (125.79 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


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In vivo
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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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