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ADC Linker

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Cat.No. Product Name Information Product Use Citations Product Validations
S0657 DSS Crosslinker DSS Crosslinker (Disuccinimidyl suberate) is a membrane permeable homobifunctional crosslinking agent and a non-cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
J Pharm Anal, 2025, 15(1):101069
Cell Death Dis, 2022, 13(6):524
S6832 MC-VC-PAB-PNP MC-Val-Cit-PAB-PNP (Mc-Val-Cit-PABC-PNP) is a cathepsin cleavable ADC peptide linker that is applicable to the synthesis of antibody-drug conjugates (ADCs).
S6669 MC-Val-Cit-PAB MC-Val-Cit-PAB, also known as MC-Val-Cit-PAB-OH, is a cathepsin cleavable ADC peptide linker and is used for making ADC conjugate (antibody-drug conjugate).
S0091 Fmoc-Val-Ala-PAB Fmoc-Val-Ala-PAB (Fmoc-Val-Ala-PAB-OH) is a useful and cleavalbe linker for making Antibody-Drug-Conjugation (ADC) conjugate for targeting drug delivery.
S0335 Boc-Val-Cit-PAB-PNP Boc-Val-Cit-PAB-PNP is a cleavable linker of ADC that is used in the synthesis of antibody-drug conjugates (ADCs).
S0566 Sulfo-SMCC sodium Sulfo-SMCC sodium is a hetero-bifunctional, noncleavable ADC crosslinker which consists of N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups.
S0586 Succinic anhydride Succinic anhydride (SA, Succinyl Oxide, Butanedioic Anhydride) is a cyclic anhydride that can be used in the homogeneous chemical modification of cellulose and as a noncleavable ADC linker that reacts with other compound to link the prodrug to an amine or hydroxy 1 group of a targeting polypeptide.
S6688 Fmoc-Val-Cit-PAB Fmoc-Val-Cit-PAB (Fmoc-Val-Cit-PAB-OH) is a cleavable linker for antibody-drug conjugates (ADC).
S0626 DSP Crosslinker DSP Crosslinker is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).
S0627 PDEC-NB PDEC-NB is a disulfide cleavable linker that can be applied into the synthesis of antibody-drug conjugates (ADCs).