Clinical Trials

Numerous clinical trials spanning phase 1 to phase 4 evaluate interventions across diverse recruitment statuses, including recruiting, active not recruiting, completed, and terminated. Research targets oncology indications such as advanced solid tumors, triple-negative breast cancer, non-small cell lung cancer, and pancreatic neoplasms, alongside non-oncology conditions like hypercholesterolemia and metabolic dysfunction-associated steatotic liver disease. These studies are sponsored by academic institutions and pharmaceutical entities, including MediLink Therapeutics, Symphogen A/S, and Fudan University.

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT07055581 RECRUITING
Small Cell Lung Cancer Limited Stage
Qian Chu
 2026-02-24 PHASE2
NCT07677930 NOT_YET_RECRUITING
Eveningness; Insomnia; Circadian Rhythm; Depressed Mood
Chinese University of Hong Kong
 2026-09-01
NCT05462106 RECRUITING
Amyloid Plaque; Beta-Amyloid; DSAD; Prodromal Alzheimer's Disease; Alzheimer's Disease
AC Immune SA
 2022-06-21 PHASE1; PHASE2
NCT06918431 RECRUITING
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative; Lymphoblastic Lymphoma
City of Hope Medical Center
 2025-10-10 PHASE2
NCT03633708 RECRUITING
Secondary Hyperparathyroidism; Chronic Kidney Disease
Amgen
 2019-04-29 PHASE3
NCT07106762 RECRUITING
Urothelial Cancer
Bristol-Myers Squibb
 2025-09-30 PHASE2; PHASE3
NCT05655260 RECRUITING
Endometrial Adenocarcinoma
University of Helsinki
 2022-02-08
NCT04199026 RECRUITING
Metastatic Sarcoma; Recurrent Sarcoma; Resectable Sarcoma
M.D. Anderson Cancer Center
 2025-02-25
NCT07315373 NOT_YET_RECRUITING
Immune Thrombocytopenia
Peking University People's Hospital
 2025-12-25 PHASE1
NCT07523009 WITHDRAWN
Severe Aplastic Anemia (SAA); Transfusion-dependent Non-severe Aplastic Anemia
Peking Union Medical College Hospital
 2026-06 PHASE2
NCT05964010 RECRUITING
Substance Use
The National Center on Addiction and Substance Abuse at Columbia University
 2024-03-01
NCT07173985 RECRUITING
Colonic Neoplasms
Ohio State University Comprehensive Cancer Center
 2026-01-20
NCT06490562 NOT_YET_RECRUITING
Acute Graft-versus-host Disease
Institute of Hematology & Blood Diseases Hospital, China
 2024-07
NCT07347743 RECRUITING
Colic; Healthy Infants; Eczema Atopic Dermatitis
Universitair Ziekenhuis Brussel
 2026-01-31
NCT05243836 ACTIVE_NOT_RECRUITING
Myopia
nthalmic Pty Ltd
 2023-08-04
NCT05683990 ACTIVE_NOT_RECRUITING
Diabetes Mellitus, Type 1; Autoimmune Diseases; Prevention
Diamyd Medical AB
 2024-07-09 PHASE2
NCT06137118 RECRUITING
B-cell Acute Lymphoblastic Leukemia (B-ALL)
AstraZeneca
 2023-12-29 PHASE1; PHASE2
NCT07437170 ACTIVE_NOT_RECRUITING
Acute Myeloid Leukemia; Pediatric Acute Myeloid Leukemia; NUP98 Fusion-positive Acute Myeloid Leukemia
The Children's Hospital of Zhejiang University School of Medicine
 2024-01-01 PHASE2
NCT07151105 RECRUITING
Adequate Vitamin C Status; Inadequate Vitamin C Status
Ohio State University
 2025-10-01
NCT06824064 RECRUITING
Metastatic Colorectal Cancer; Advanced Colorectal Cancer
Riboscience, LLC.
 2025-01-17 PHASE2
NCT06585085 RECRUITING
Pregnant Woman
University Hospital, Clermont-Ferrand
 2024-09-10
NCT05845021 RECRUITING
Osteoporosis; Arthroplasty Complications; Fragility Fracture
Johns Hopkins University
 2023-09-27
NCT07020247 RECRUITING
Locally Advanced Rectal Cancer (LARC); Immunotherapy; Radiotherapy; Total Neoadjuvant Therapy; Anal Function Preservation
West China Hospital
 2024-11-19 PHASE3
NCT06563700 ACTIVE_NOT_RECRUITING
Myopia, Progressive
Shanghai Eye Disease Prevention and Treatment Center
 2024-08-16
NCT03604315 RECRUITING
Breast Carcinoma; Fallopian Tube Carcinoma; Ovarian Carcinoma; Primary Peritoneal Carcinoma; Recurrent Fallopian Tube Carcinoma; Recurrent Ovarian Carcinoma; Recurrent Primary Peritoneal Carcinoma; Solid Neoplasm
M.D. Anderson Cancer Center
 2018-12-18 PHASE1
NCT06941675 RECRUITING
Latent Autoimmune Diabetes in Adults (LADA)
Shanxi Bethune Hospital
 2025-04-01
NCT07566091 NOT_YET_RECRUITING
Coronary Artery Disease
Jung-min Ahn
 2026-06-15
NCT07659795 RECRUITING
Colorectal Cancer
Verastem, Inc.
 2026-07-28 PHASE2
NCT06872593 RECRUITING
Excessive Daytime Sleepiness; Obstructive Sleep Apnea (OSA); CPAP Treatment; Driving Simulator Performance; Driving Impaired; CPAP
Stefan Lakämper
 2025-07-14
NCT05046353 SUSPENDED
Schizophrenia; Schizo Affective Disorder
New York State Psychiatric Institute
 2022-12-01 PHASE1; PHASE2
NCT06048484 RECRUITING
Pancreatic Ductal Adenocarcinoma
Gulam Manji
 2024-05-10 PHASE2
NCT07568509 RECRUITING
Arginine Vasopressin Deficiency; Oxytocin Deficiency; Pediatric Disease; Hypopituitarism
Massachusetts General Hospital
 2026-08-17 EARLY_PHASE1
NCT05558319 RECRUITING
Newly Diagnosed Multiple Myeloma
PETHEMA Foundation
 2022-11-10 PHASE3
NCT07546396 NOT_YET_RECRUITING
Opioid Use Disorder
Pouya Azar
 2026-05 PHASE4
NCT05336955 ACTIVE_NOT_RECRUITING
Mental Health Conditions; Developmental Disability
University of New Hampshire
 2023-05-01
NCT01804634 RECRUITING
Refractory and/or Relapsed Metastatic Solid Tumors
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
 2013-03-27 PHASE2
NCT06470191 RECRUITING
Primary Membranous Nephropathy
Shanghai Jiaolian Drug Research and Development Co., Ltd
 2024-07-30 PHASE2; PHASE3
NCT06775743 RECRUITING
NSCLC (Advanced Non-small Cell Lung Cancer); EGFR Mutation Positive Advanced Non Small Cell Lung Cancer
Fudan University
 2025-01-15 PHASE2
NCT06809192 RECRUITING
Multiple Sclerosis
University of Washington
 2025-01-10
NCT06750991 NOT_YET_RECRUITING
DLBCL
Ruijin Hospital
 2024-12-31 PHASE2
NCT06295250 RECRUITING
Depression; Economic Vulnerability; Anxiety; Culture Specific Symptoms
University of Massachusetts, Worcester
 2024-03-01
NCT05781321 ACTIVE_NOT_RECRUITING
Glioblastoma
Mayo Clinic
 2023-03-23 PHASE2
NCT06107686 RECRUITING
NSCLC; Breast Cancer; HNSCC; Locally Advanced or Metastatic Solid Tumors
MediLink Therapeutics (Suzhou) Co., Ltd.
 2023-12-15 PHASE2
NCT04041310 ACTIVE_NOT_RECRUITING
Solid Tumor, Adult
Nouscom SRL
 2019-10-21 PHASE1; PHASE2
NCT07351643 NOT_YET_RECRUITING
ACS (Acute Coronary Syndrome); SGLT2 Inhibitors
Shenyang Northern Hospital
 2026-02-25 PHASE4
NCT06758726 NOT_YET_RECRUITING
AML
Institute of Hematology & Blood Diseases Hospital, China
 2024-12-31
NCT07636746 ACTIVE_NOT_RECRUITING
Morbid Obesity
Ain Shams University
 2026-04-17
NCT03528642 ACTIVE_NOT_RECRUITING
Astrocytoma, IDH-Mutant, Grade 2; Astrocytoma, IDH-Mutant, Grade 3
National Cancer Institute (NCI)
 2019-05-01 PHASE1
NCT05554419 NOT_YET_RECRUITING
Acute Myeloid Leukemia; Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Acute Myeloid Leukemia Arising From Previous Myeloproliferative Neoplasm; Acute Myeloid Leukemia Post Cytotoxic Therapy; Secondary Acute Myeloid Leukemia
National Cancer Institute (NCI)
 2026-07-01 PHASE2
NCT06993662 COMPLETED
Anxiety; Depression; Obsessive-compulsive Disorder; Personality Disorder; Bipolar Disorder; Schizophrenia; Psychotic Disorders; PTSD
Rakitzi, Stavroula
 2025-06-02 PHASE1
NCT07399197 RECRUITING
Malocclusion; Displaced Teeth
Sana'a University
 2026-03-02
NCT07526584 RECRUITING
Nutrition; Obesity & Overweight
University of North Carolina, Chapel Hill
 2026-08-01
NCT07476144 ACTIVE_NOT_RECRUITING
Smoking Behaviors
JT International SA
 2026-01-08 PHASE1
NCT07597096 NOT_YET_RECRUITING
Postoperative Symptomatic Hypocalcemia Following Total Thyroidectomy
King Edward Medical University
 2026-05-10
NCT07445464 NOT_YET_RECRUITING
Pharmacokinetic Analysis
Aspartes Pharmaceuticals, Inc.
 2026-04-09 PHASE1
NCT07533617 COMPLETED
Coccydynia
KTO Karatay University
 2026-05-01
NCT06979141 RECRUITING
Cough
Al-Azhar University
 2025-06-02 PHASE3
NCT05778604 UNKNOWN
Fall; Fear of Falling; Physical Inactivity; Sedentary Behavior
University of Central Florida
 2023-04-12
NCT06589765 COMPLETED
Type 2 Diabetes
Shandong Suncadia Medicine Co., Ltd.
 2024-09-27 PHASE3
NCT06948929 RECRUITING
Alzheimer Disease
Chinese University of Hong Kong
 2025-05-15
NCT07366970 RECRUITING
Diabetes Mellitus; Erectile Dysfunction; Vitamin D Deficiency
Cairo University
 2025-12-05
NCT07223216 ACTIVE_NOT_RECRUITING
Obesity
Biomea Fusion Inc.
 2025-10-23 PHASE1
NCT06877208 ACTIVE_NOT_RECRUITING
Cerebral Glucose Metabolism
Nicolai Jacob Wewer Albrechtsen
 2025-03-18
NCT05380661 COMPLETED
Spinal Cord Injuries; Urinary Bladder, Neurogenic; Anxiety State; Catheter Complications; Autonomic Dysreflexia
University of British Columbia
 2022-07-15
NCT07484048 COMPLETED
Cognitive Impairment; Coginitive Assessment
Gloucestershire Hospitals NHS Foundation Trust
 2025-09-15
NCT07207291 RECRUITING
Bacterial Infections; Urinary Tract Infections; Intra-Abdominal Infections; Respiratory Tract Infections
Joincare Pharmaceutical Group Industry Co., Ltd
 2025-08-22 PHASE1
NCT06155084 RECRUITING
Metastatic Castration-resistant Prostate Cancer
Hinova Pharmaceuticals Inc.
 2023-12-26 PHASE1; PHASE2
NCT06700395 RECRUITING
Multiple Myeloma
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.
 2024-11-28 PHASE1
NCT05501665 RECRUITING
Lung Non-Small Cell Carcinoma; Stage IV Lung Cancer AJCC v8; Stage III Lung Cancer
Vanderbilt-Ingram Cancer Center
 2023-05-09 PHASE1; PHASE2
NCT06513013 COMPLETED
Cesarean Section
Assiut University
 2023-12-20 PHASE2; PHASE3
NCT03548246 WITHDRAWN
Congenital Adrenal Hyperplasia
University of Texas Southwestern Medical Center
 2023-01 PHASE2
NCT06126354 WITHDRAWN
Insulin Resistance; Prediabetic State; Non-Alcoholic Fatty Liver Disease; Overweight and Obesity
Columbia University
 2024-07-01 PHASE1
NCT07310524 COMPLETED
Opioid-free Anesthesia
Muhammad Rahman Efendi Nasution
 2025-09-08
NCT06145282 ACTIVE_NOT_RECRUITING
Sickle Cell Disease
National Heart, Lung, and Blood Institute (NHLBI)
 2023-12-28 PHASE1; PHASE2
NCT04722146 ACTIVE_NOT_RECRUITING
Multiple Myeloma
Janssen Research & Development, LLC
 2021-03-12 PHASE1
NCT05430802 ACTIVE_NOT_RECRUITING
Non-small Cell Lung Cancer
Tang-Du Hospital
 2022-02-24 PHASE2
NCT03073967 COMPLETED
HSV Infection
AiCuris Anti-infective Cures AG
 2017-05-08 PHASE3
NCT03647163 ACTIVE_NOT_RECRUITING
Solid Tumor; Non Small Cell Lung Cancer; Neuroendocrine Carcinoma; Renal Cell Carcinoma (RCC)
Vyriad, Inc.
 2019-04-09 PHASE1; PHASE2
NCT02416388 RECRUITING
Acute Myeloid Leukemia (AML)
University Hospital, Angers
 2015-01 PHASE2; PHASE3
NCT02179086 ACTIVE_NOT_RECRUITING
Glioblastoma
NRG Oncology
 2014-12-04 PHASE2
NCT04046575 ACTIVE_NOT_RECRUITING
Esophagus Cancer; Esophageal Cancer; Cancer of the Esophagus
Washington University School of Medicine
 2019-11-07 PHASE1
NCT05348213 RECRUITING
Diffuse Large B Cell Lymphoma
Ruijin Hospital
 2022-05-16 PHASE2
NCT05100121 RECRUITING
Prostate Cancer
Karolinska Institutet
 2023-10-17
NCT06875388 ACTIVE_NOT_RECRUITING
Cognitive Functioning of Healthy Individuals; Balance; Strength, Muscle; Quality of Life (QOL)
Shifa Tameer-e-Millat University
 2025-01-09
NCT05129631 COMPLETED
Congenital Heart Disease
Nemours Children's Clinic
 2023-07-14
NCT05609370 ACTIVE_NOT_RECRUITING
Unresectable or Metastatic Microsatellite Stable/Mismatch Repair Proficient Colorectal Cancer
BeiGene
 2023-01-29 PHASE1; PHASE2
NCT04586348 UNKNOWN
Pregnancy Related; Neurodevelopmental Disorders; Nutrition Disorder, Fetal
South Australian Health and Medical Research Institute
 2021-01-18 PHASE4
NCT06832566 NOT_YET_RECRUITING
Secondary Adrenal Insufficiency; Hypotension
Hopital La Rabta
 2025-02-15 PHASE4
NCT06347835 UNKNOWN
Sarcopenia
Peking Union Medical College Hospital
 2024-04
NCT06775418 NOT_YET_RECRUITING
Analgesia, Postoperative
Ain Shams University
 2025-01
NCT06294067 COMPLETED
Nutrition, Healthy
University of Toronto
 2024-02-26 PHASE1
NCT06576479 RECRUITING
Chronic Kidney Diseases; Protein-Energy Malnutrition
NIN Institute
 2018-07-10
NCT06345755 COMPLETED
Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Vertex Pharmaceuticals Incorporated
 2024-04-17 PHASE1
NCT05765344 COMPLETED
Hepatic Impairment; Healthy
Gilead Sciences
 2023-03-15 PHASE1
NCT06359899 COMPLETED
ADHD
Shanghai Ark Biopharmaceutical Co., Ltd.
 2024-05-28 PHASE3
NCT03396068 UNKNOWN
Bipolar Depression; Suicidal Ideation
NeuroRx, Inc.
 2019-12-01 PHASE3
NCT01419730 ACTIVE_NOT_RECRUITING
Bone Metabolism Biomarkers; Bone Mineral Density; Physical Fitness
University of Rochester
 2011-08 PHASE2
NCT05401058 TERMINATED
Digestive System Disease; Urologic Diseases; Gynecological Disease; Orthopedic Surgery
RenJi Hospital
 2022-11-21
NCT03686202 ACTIVE_NOT_RECRUITING
All Solid Tumors
University Health Network, Toronto
 2018-11-30 PHASE2; PHASE3
NCT05715424 UNKNOWN
Myopia; Refractive Errors
Anhui Medical University
 2022-12-01
NCT04462965 UNKNOWN
Mucosal Melanoma
Peking University Cancer Hospital & Institute
 2020-05-30 PHASE2
NCT03369223 COMPLETED
Advanced Cancer
Bristol-Myers Squibb
 2017-12-06 PHASE1; PHASE2
NCT05714956 COMPLETED
Perinatal Depression
Northwestern University
 2023-03-01
NCT04247620 COMPLETED
Type 1 Diabetes
Baylor College of Medicine
 2020-12-15 PHASE2
NCT06261086 UNKNOWN
Vitiligo
Sohag University
 2024-02-24
NCT06422039 COMPLETED
Type 2 Diabetes Mellitus
Shandong Suncadia Medicine Co., Ltd.
 2024-05-23 PHASE1
NCT06345131 UNKNOWN
Surgical Patients
Nanjing First Hospital, Nanjing Medical University
 2023-07-01
NCT04774523 COMPLETED
Heart Failure; Cardiac Arrhythmia; Left Ventricular Dysfunction
Biotronik SE & Co. KG
 2021-08-31
NCT02964013 COMPLETED
Neoplasms
Merck Sharp & Dohme LLC
 2016-12-13 PHASE1
NCT05195151 COMPLETED
COVID-19; Vaccine Reaction; Elderly
Université de Sherbrooke
 2022-11-10
NCT03334656 TERMINATED
Split Thickness Skin Graft; Wound Healing
Nantes University Hospital
 2018-05-16 PHASE1; PHASE2
NCT06719115 COMPLETED
Urinary Tract Infection(UTI)
KEB Nutraceuticals USA, Inc.
 2023-05-03 PHASE2
NCT05174026 COMPLETED
Metastatic Malignant Neoplasm; Metastatic Malignant Neoplasm in the Bone
M.D. Anderson Cancer Center
 2018-11-30
NCT06516380 COMPLETED
Mosaicplasty; Cyberdyne; Single Joint; TecnoBody
Ankara Yildirim Beyazıt University
 2024-05-30
NCT05457517 UNKNOWN
Advanced Solid Tumors
Shanghai YingLi Pharmaceutical Co. Ltd.
 2022-09-24 PHASE1; PHASE2
NCT05953545 WITHDRAWN
Chronic Hepatitis Delta
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
 2024-05-22 PHASE2
NCT03522246 ACTIVE_NOT_RECRUITING
Epithelial Ovarian Cancer; Primary Peritoneal; Fallopian Tube Cancer; Newly Diagnosed; FIGO Stage III-IV; Partial Response; Complete Response
pharmaand GmbH
 2018-05-14 PHASE3
NCT07453680 COMPLETED
PCOS (Polycystic Ovary Syndrome)
Mst.Sumyara Khatun
 2023-06-01
NCT05651490 UNKNOWN
Diabetes Mellitus, Type 2
Singapore Eye Research Institute
 2020-03-09
NCT05252364 COMPLETED
Metastatic Castration-resistant Prostate Cancer
Hinova Pharmaceuticals Aus Pty Ltd
 2021-12-14 PHASE1
NCT05672420 UNKNOWN
Hematologic Neoplasms; Neutropenia; Anemia; Thrombocytopenia; Infections; Bleeding
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
 2023-01-01 PHASE1; PHASE2
NCT04912115 SUSPENDED
Dyskinesias; Movement Disorders; Central Nervous System Diseases; Nervous System Diseases; Neurologic Manifestations
PharmaTher Inc.
 2021-10-05 PHASE2
NCT05954923 COMPLETED
Healthy
University Hospital, Gentofte, Copenhagen
 2023-09-05
NCT04840121 COMPLETED
Fertility
Clinique Ovo
 2021-03-24
NCT04590131 UNKNOWN
Atherosclerosis; Ischemia Limb; Superficial Femoral Artery Occlusion; Popliteal Artery Occlusion; Stent Complication
Meshalkin Research Institute of Pathology of Circulation
 2020-11-01
NCT05351489 COMPLETED
Transurethral Resection of Prostate
Mansoura University
 2022-05-30 EARLY_PHASE1
NCT04561167 COMPLETED
Endodontically Treated Teeth
Cairo University
 2020-10-01
NCT05207488 UNKNOWN
Overweight and Obesity
University of Illinois at Urbana-Champaign
 2021-10-01
NCT07237113 COMPLETED
Damage Muscle
Instituto de Ciencias de la Salud, Universidad de O'Higgins
 2021-09-01
NCT07554196 COMPLETED
Solid Tumor
Huahui Health
 2022-01-19 PHASE1
NCT04890626 COMPLETED
SARS-CoV-2 Infection
Instituto de Investigación Hospital Universitario La Paz
 2020-04-04 PHASE3
NCT05701813 UNKNOWN
Obesity; Prediabetic State; Dyslipidemias; Insulin Resistance
Azienda Ospedaliera Universitaria Integrata Verona
 2023-02-01
NCT01236560 COMPLETED
Brain Stem Glioma; Cerebral Astrocytoma; Childhood Cerebellar Anaplastic Astrocytoma; Childhood Cerebral Anaplastic Astrocytoma; Childhood Spinal Cord Neoplasm
National Cancer Institute (NCI)
 2011-01-26 PHASE2; PHASE3
NCT03280667 UNKNOWN
Renal Cell Carcinoma, Clear Cell; Metastatic Kidney Cancer
Australian and New Zealand Urogenital and Prostate Cancer Trials Group
 2017-12-12 PHASE2
NCT03815461 UNKNOWN
Locally Advanced Pancreatic Cancer
Chinese Academy of Medical Sciences
 2019-02-01 PHASE2
NCT02926521 WITHDRAWN
Regional Anesthesia Morbidity
Boston Children's Hospital
 2021-12-01
NCT07520422 COMPLETED
IBS-D (Diarrhea-predominant)
Bioagile Therapeutics Pvt. Ltd.
 2023-02-25
NCT05479773 UNKNOWN
Respiratory Failure
Inspir Labs Ltd.
 2022-06-23
NCT04019444 COMPLETED
Rabies; Rabies Immunisation
National Institute of Allergy and Infectious Diseases (NIAID)
 2019-09-19 PHASE1
NCT04451187 COMPLETED
Depressive Disorder, Major
Janssen Research & Development, LLC
 2020-07-16 PHASE1
NCT05437120 COMPLETED
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated
 2022-07-22 PHASE1
NCT05328583 UNKNOWN
Human Immunodeficiency Virus-1 (HIV-1) Infection
RetroLead (Shanghai) BioPharma Co., Ltd.
 2022-04-15 PHASE1
NCT04842318 UNKNOWN
Follicular Lymphoma
Ruijin Hospital
 2021-03-01 PHASE4
NCT04280601 COMPLETED
ANCA-associated Vasculitis; Granulomatosis With Polyangiitis; Microscopic Polyangiitis; Eosinophilic Granulomatosis With Polyangiitis
Christian Pagnoux
 2020-08-01
NCT03310619 COMPLETED
Lymphoma, Non-Hodgkin; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Follicular
Celgene
 2017-12-20 PHASE1; PHASE2
NCT05245396 COMPLETED
Healthy
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
 2022-02-02 PHASE1
NCT05711810 COMPLETED
Severe Acute Respiratory Syndrome-related Coronavirus; Renal Dialysis; Vaccines; Myocarditis Allergic; Infection Viral
Yang I. Pachankis
 2023-01-02 PHASE4
NCT04825418 UNKNOWN
Hypothermia
Seoul National University Hospital
 2021-05
NCT06000800 COMPLETED
Cord Clamping
Cairo University
 2021-11-18
NCT03071185 UNKNOWN
Elective Reconstructive Surgery; Pain, Post Operative
Xia Zhang
 2017-01-20
NCT04581317 COMPLETED
Dementia
The University of Texas Health Science Center, Houston
 2021-01-19
NCT04564612 COMPLETED
Healthy Volunteers
Biogen
 2020-09-28 PHASE1
NCT02717520 UNKNOWN
Dental Restoration
University of Zagreb
 2015-09
NCT05047770 COMPLETED
Herpes Zoster
GlaxoSmithKline
 2021-10-07 PHASE3
NCT04061876 COMPLETED
aGVHD; Stem Cell Transplant Complications
Chinese PLA General Hospital
 2019-08-25 PHASE2
NCT04461405 COMPLETED
Type II Diabetes; Primary Health Care; Behavioral Health
Oregon Health and Science University
 2020-03-01
NCT04531397 WITHDRAWN
Proteinuria; Chronic Kidney Diseases
Children's Hospital of Fudan University
 2021-01-01 PHASE4
NCT04818957 COMPLETED
Vitamin D Deficiency; Hematopoietic Stem Cell Transplantation (HSCT)
Children's Hospital Medical Center, Cincinnati
 2021-06-07
NCT04480190 WITHDRAWN
Cholangiocarcinoma; Biliary Cancer
Jordan Kharofa
 2021-02-04 PHASE1
NCT04117581 COMPLETED
Asthma; Vitamin D Deficiency; Nutritional Deficiency; Inflammation
University of Chester
 2019-10-28
NCT03539328 UNKNOWN
Ovarian Cancer
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
 2018-06 PHASE2
NCT05034120 COMPLETED
Healthy
Xuanzhu Biopharmaceutical Co., Ltd.
 2021-12-23 PHASE1
NCT04762745 UNKNOWN
Relapsed, Refractory, Multiple Myeloma
Sun Yat-sen University
 2021-02 PHASE1; PHASE2
NCT04940884 COMPLETED
Aging
Chang Gung Memorial Hospital
 2021-07-01
NCT04147767 UNKNOWN
Hypercholesterolemia; Breast Cancer; Obesity
University of Leeds
 2020-02-10
NCT04713319 COMPLETED
Healthy Participants
Petteri Hirvonen
 2019-10-04 EARLY_PHASE1
NCT04966884 UNKNOWN
Dermatomyositis, Adult Type
First Affiliated Hospital Xi'an Jiaotong University
 2020-04-02 PHASE4
NCT05431218 COMPLETED
Chronic Obstructive Pulmonary Disease; Chronic Obstructive Pulmonary Disease Moderate; Chronic Obstructive Pulmonary Disease Severe
Karaganda Medical University
 2020-02-18 PHASE4
NCT04063124 COMPLETED
Alzheimer Disease
The University of Texas Health Science Center at San Antonio
 2020-02-14 PHASE1; PHASE2
NCT05779410 COMPLETED
Healthy
Taipei Medical University
 2021-01-20
NCT04373395 UNKNOWN
Acute Myeloid Leukemia
Zhejiang University
 2020-01-01
NCT04936490 UNKNOWN
Chorioretinopathy, Central Serous
Shiraz University of Medical Sciences
 2021-07-01 PHASE1
NCT03949140 COMPLETED
Pilonidal Disease
University of Wisconsin, Madison
 2019-02-18
NCT04916925 UNKNOWN
Vitamin D Deficiency; Clomiphene Allergy; Polycystic Ovary Syndrome
rana alaaeldin aly ibrahim nasr
 2021-08-21 PHASE1; PHASE2
NCT04128163 UNKNOWN
Postmenopausal Osteoporosis
Qilu Pharmaceutical Co., Ltd.
 2019-06-05 PHASE3
NCT03812380 TERMINATED
Osteoporosis; Hypomagnesemia
University of Texas Southwestern Medical Center
 2019-01-01 PHASE3
NCT03254654 COMPLETED
Advanced Triple-Negative Breast Cancer
Fudan University
 2017-08-16 PHASE2
NCT04506281 UNKNOWN
Cholangiocarcinoma, Intrahepatic
Shanghai Zhongshan Hospital
 2020-08-10 PHASE2
NCT04500418 TERMINATED
Covid19
Charite University, Berlin, Germany
 2020-08-25 PHASE2
NCT04959318 COMPLETED
Metabolic Syndrome
Madigan Army Medical Center
 2019-11-20
NCT03624530 UNKNOWN
Philadelphia Chromosome Positive Acute Lymphocytic Leukemia; Tyrosine Kinase Inhibitor; Minimal Residual Disease; Allogeneic Hematopoietic Stem Cell Transplantation
Nanfang Hospital, Southern Medical University
 2018-08 PHASE2; PHASE3
NCT04051645 UNKNOWN
Healthy
Czech Technical University in Prague
 2019-06-24
NCT03019497 COMPLETED
PTSD
Université de Montréal
 2017-01
NCT03336333 ACTIVE_NOT_RECRUITING
Chronic Lymphocytic Leukemia; Small Lymphocytic Lymphoma
BeiGene
 2017-10-31 PHASE3
NCT04483635 TERMINATED
COVID-19
St. Justine's Hospital
 2021-02-08 PHASE3
NCT03046927 COMPLETED
Type 1 Diabetes
Benjamin U. Nwosu, MD
 2017-10-19 PHASE2; PHASE3
NCT04707820 COMPLETED
Corona Virus Infection
University Hospital, Rouen
 2020-04-16
NCT03438331 COMPLETED
Insomnia; Depression
The University of Hong Kong
 2018-05-15
NCT04208061 COMPLETED
Healthy
Janssen Research & Development, LLC
 2019-12-18 PHASE1
NCT04810949 TERMINATED
Covid19; Influenza A; Influenza B; H1N1 Influenza
Hospital Clinica Nova
 2020-08-05
NCT04837781 COMPLETED
Tooth Position Anomalies
University of Baghdad
 2019-02-23
NCT04365270 COMPLETED
Reversible Pulpitis; Pulpitis; Caries,Dental; Caries Class I; Caries; Dentin; Caries
Ain Shams University
 2019-01-15 PHASE3
NCT03732807 COMPLETED
Alopecia Areata
Pfizer
 2018-12-03 PHASE2; PHASE3
NCT04427215 UNKNOWN
Breast Cancer
Klaipėda University
 2020-07-01 PHASE1
NCT04468958 COMPLETED
COVID-19; SARS-CoV2
SAb Biotherapeutics, Inc.
 2020-07-01 PHASE1
NCT03986268 COMPLETED
Vitamin D Deficiency; Chemotherapy Effect; Pathology
Florence Nightingale Hospital, Istanbul
 2019-05-10
NCT02959762 UNKNOWN
Obesity; Insulin Resistance; Obesity in Diabetes; Nutritional and Metabolic Diseases; Hyperlipidemia; Hyperglycemia; Cardiovascular Diseases
Augusta University
 2016-10
NCT01691625 COMPLETED
Esophageal Carcinoma
Capital Medical University
 2012-09
NCT05122312 COMPLETED
Dentin Hypersensitivity
Al-Azhar University
 2020-04-20 PHASE4
NCT04478357 COMPLETED
Neurogenic Detrusor Overactivity
Pfizer
 2019-11-12 PHASE1
NCT04301336 COMPLETED
Vaso-occlusive Crisis; Sickle Cell Disease; Sickle Cell Anemia in Children
Beni-Suef University
 2019-11-01 PHASE2; PHASE3
NCT02936375 UNKNOWN
Lupus Nephritis
RenJi Hospital
 2017-09-07 PHASE2
NCT04530578 UNKNOWN
Covid19; Pneumonia
Clinica San Camilo, Argentina
 2020-06-01 PHASE4
NCT02647255 TERMINATED
Glomerulonephritis, IGA; Kidney Diseases; Acute Renal Insufficiency; Rapidly Progressive Glomerulonephritis
Peking University First Hospital
 2016-03 PHASE2; PHASE3
NCT03089281 COMPLETED
Heart Failure
Boston Scientific Corporation
 2017-08-01
NCT03639142 UNKNOWN
Functional Constipation
Medical University of Warsaw
 2018-09-01 PHASE3
NCT03901937 UNKNOWN
Crohn Disease
Sir Run Run Shaw Hospital
 2019-03-01 PHASE4
NCT02293057 COMPLETED
Drug Use
University of California, San Francisco
 2014-09
NCT04026334 TERMINATED
Wound; Wound Heal; Wounds and Injuries; Granulation Tissue; Negative-pressure Wound Therapy
3M
 2019-07-25
NCT02824718 COMPLETED
Autosomal Dominant Hypocalcemia OR Primary Hypoparathyroidism Related to Other Cause But Complicated by Hypercalciuria Under Treatment
Assistance Publique - Hôpitaux de Paris
 2017-06-06 PHASE2
NCT03701321 WITHDRAWN
Recurrent Plasma Cell Myeloma; Refractory Plasma Cell Myeloma
National Cancer Institute (NCI)
 2019-01-25 PHASE1; PHASE2
NCT04223349 COMPLETED
Healthy
Janssen Research & Development, LLC
 2020-01-10 PHASE1
NCT01363128 COMPLETED
Acute Lymphoblastic Leukemia; Adult Acute Lymphoblastic Leukemia in Complete Remission; Burkitt Leukemia; Burkitt Lymphoma; CD20 Positive; Childhood Acute Lymphoblastic Leukemia in Complete Remission; Lymphoblastic Lymphoma
M.D. Anderson Cancer Center
 2011-07-12 PHASE2
NCT02942758 TERMINATED
Acute Myeloid Leukemia
University Hospital Regensburg
 2017-04-10 PHASE2
NCT04073121 COMPLETED
Critical Limb Ischemia
Singapore General Hospital
 2018-12-27
NCT03713242 COMPLETED
Hepatic Impairment
Idorsia Pharmaceuticals Ltd.
 2018-02-26 PHASE1
NCT03397095 UNKNOWN
Ischemic Heart Disease
Shanghai 10th People's Hospital
 2018-04-03 PHASE1; PHASE2
NCT02858804 COMPLETED
Mantle Cell Lymphoma
Institute of Hematology & Blood Diseases Hospital, China
 2016-01 PHASE4
NCT02262299 COMPLETED
Disorder Related to Lung Transplantation; CLAD, Bronchiolitis Obliterans
Rigshospitalet, Denmark
 2015-05 PHASE2; PHASE3
NCT03584802 TERMINATED
Exacerbation of Idiopathic Pulmonary Fibrosis
Assistance Publique - Hôpitaux de Paris
 2019-05-16
NCT04500743 COMPLETED
IVF; Endometriosis; Pregnancy Rate; Progestins; GnRH-analogue
National Research Centre, Egypt
 2018-08-01
NCT04004663 COMPLETED
Healthy Volunteers
Pfizer
 2019-07-15 PHASE1
NCT03867461 COMPLETED
Idiopathic Intracranial Hypertension
Wake Forest University Health Sciences
 2019-06-20
NCT03349606 COMPLETED
Cocaine Dependence
University of Pittsburgh
 2010-06-02 EARLY_PHASE1
NCT04071574 COMPLETED
Female Infertility; Female Infertility Due to Ovulatory Disorder; Premature Ovarian Failure; Polycystic Ovary Syndrome; Female Infertility of Tubal Origin; Ectopic Pregnancy; Salpingitis; Female Infertility Due to Tubal Block; Female Infertility Due to Tubal Occlusion; Hydrosalpinx; Female Infertility - Cervical/Vaginal; Female Infertility Endocrine; Endometriosis; Fibroids; Congenital Uterine Anomaly; Infections Uterine; Female Infertility of Other Origin
Lebanese University
 2018-02-01 PHASE1; PHASE2
NCT04593524 COMPLETED
Tuberculosis
Universitas Sumatera Utara
 2019-05-14
NCT03685305 COMPLETED
Overweight and Obesity
Virginia Polytechnic Institute and State University
 2018-08-06
NCT02906670 TERMINATED
Oncology
Symphogen A/S
 2016-11-01 PHASE1; PHASE2
NCT03531177 COMPLETED
Type2 Diabetes
King's College London
 2018-04-26
NCT02404870 COMPLETED
Healthy Volunteers
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
 2014-09-16 PHASE1
NCT00965900 UNKNOWN
Variceal Bleeding; Cirrhosis
Korea University
 2006-09 PHASE4
NCT02897596 UNKNOWN
Hepatitis C; HIV
Fundacion Clinic per a la Recerca Biomédica
 2017-04-28 PHASE3
NCT03804645 COMPLETED
Heart Failure
AstraZeneca
 2019-02-05 PHASE1
NCT03498989 UNKNOWN
Neonatal SEPSIS; Weight Gain; Feeding Disorder Neonatal
Assiut University
 2018-06-21
NCT03668860 COMPLETED
Preterm Birth; Antenatal Corticosteroids
Children's Hospital Medical Center, Cincinnati
 2018-09-20 PHASE1
NCT03315338 COMPLETED
Healthy
Corcept Therapeutics
 2017-09-15 PHASE1
NCT03020745 COMPLETED
Hepatitis B
GlaxoSmithKline
 2017-02-14 PHASE2
NCT03468803 COMPLETED
Invasive Candidiases
Medical University of Graz
 2018-03-01
NCT02624310 WITHDRAWN
HSAN Type IV
NYU Langone Health
 2016-01 PHASE2
NCT02464423 COMPLETED
Human Immunodeficiency Virus
Hektoen Institute for Medical Research
 2013-01
NCT02272790 COMPLETED
Ovarian, Fallopian Tube, Peritoneal Cancer, P53 Mutation
AstraZeneca
 2015-01-30 PHASE2
NCT03291249 WITHDRAWN
NASH - Nonalcoholic Steatohepatitis; NAFLD; T2DM (Type 2 Diabetes Mellitus)
Tiziana Life Sciences LTD
 2017-12-01 PHASE2
NCT03162237 COMPLETED
Type 1 Diabetes
Wei Wang,MD
 2013-07
NCT02457910 TERMINATED
Estrogen Receptor Negative; Estrogen Receptor Positive; HER2/Neu Negative; Progesterone Receptor Negative; Progesterone Receptor Positive; Stage IV Breast Cancer; Triple-Negative Breast Carcinoma
Vanderbilt-Ingram Cancer Center
 2015-06 PHASE1; PHASE2
NCT02561962 COMPLETED
Multiple Myeloma
Amgen
 2015-11-20 PHASE1
NCT03251482 COMPLETED
VTE Prophylaxis With Anticoagulation After Total Knee Replacement Surgery
Janssen Research & Development, LLC
 2017-11-13 PHASE2
NCT01295827 COMPLETED
Cancer, Solid Tumor
Merck Sharp & Dohme LLC
 2011-03-04 PHASE1
NCT01759771 COMPLETED
Prostate Cancer
VA Office of Research and Development
 2013-01-03 PHASE2
NCT02917967 COMPLETED
Cerebral Palsy
Yonsei University
 2016-11-15
NCT02891070 COMPLETED
Cerebrospinal Fluid Leak
Baxter Healthcare Corporation
 2016-10-11 PHASE3
NCT02933190 UNKNOWN
Magnetic Resonance Imaging; Ovarian Function; Menstruation
Shanghai First Maternity and Infant Hospital
 2016-11
NCT04997122 COMPLETED
Healthy; Hypercholesterolemia
Instituto de Ciencia y Tecnología de Alimentos y Nutrición
 2018-04-02
NCT03367663 COMPLETED
Atherosclerosis; Dyslipidemias; Diabetes
Prof. Tony hayek MD
 2018-01-17 EARLY_PHASE1
NCT03835637 COMPLETED
Healthy Volunteers
ORIC Pharmaceuticals
 2018-03-23 PHASE1
NCT02422784 WITHDRAWN
Vitamin D Deficiency
University of Manitoba
 2016-07 PHASE1
NCT02622074 COMPLETED
Triple Negative Breast Neoplasms
Merck Sharp & Dohme LLC
 2016-01-27 PHASE1
NCT03216278 COMPLETED
Healthy Subjects in Fasted and Fed State
AstraZeneca
 2017-09-26 PHASE1
NCT02507609 COMPLETED
Hip Fractures
Konkuk University Medical Center
 2015-09-08
NCT00875342 TERMINATED
Posttraumatic Stress Disorder
Weill Medical College of Cornell University
 2008-05
NCT02404623 COMPLETED
Other Preterm Infants; Vitamin D Deficiency; Bronchiolitis; Asthma; Pneumonia
Soroka University Medical Center
 2015-04
NCT02132481 COMPLETED
Substance Use Disorder (SUD); Recovery
Chestnut Health Systems
 2015-06
NCT03227445 COMPLETED
Pulmonary Disease, Chronic Obstructive
GlaxoSmithKline
 2017-09-20 PHASE4
NCT03134443 UNKNOWN
Acute Tonsillitis
Jiangxi Qingfeng Pharmaceutical Co. Ltd.
 2016-12-01 PHASE4
NCT03023748 UNKNOWN
Endstage Renal Disease; Secondary Hyperparathyroidism
The University of Hong Kong
 2011-09 PHASE4
NCT02462824 COMPLETED
Peripheral Artery Disease
Northwestern University
 2015-04
NCT03260764 UNKNOWN
Multifocal Contact Lenses
Sun Yat-sen University
 2017-08-20
NCT03846843 COMPLETED
Cirrhosis
Ocera Therapeutics, Inc.
 2016-08-15 PHASE1
NCT03200080 TERMINATED
Abuse Potential
Biotie Therapies Inc.
 2017-09-18 PHASE1
NCT01721915 COMPLETED
Polycystic Ovary Syndrome; Healthy; Vitamin D Deficiency
Medical University of Graz
 2012-10 PHASE4
NCT02561091 COMPLETED
Hearing Loss
Auris Medical AG
 2015-11 PHASE3
NCT04113343 COMPLETED
Safety Issues
Paion UK Ltd.
 2017-05-30 PHASE1
NCT02918266 TERMINATED
Healthy Volunteers
Takeda
 2016-11-21 PHASE1
NCT02507323 WITHDRAWN
Cardiovascular Disease
Yochai Birnbaum
 2016-02 PHASE2
NCT01824940 COMPLETED
Growth; Stunting, Nutritional; Anemia
Johns Hopkins Bloomberg School of Public Health
 2012-11
NCT03066713 COMPLETED
Glycemic Response; Appetitive Behavior
Purdue University
 2017-01-31
NCT03198676 COMPLETED
Upper Respiratory Tract Infections
Prep Biopharm Limited
 2017-05-08 PHASE1
NCT00828386 TERMINATED
Nasopharyngeal Cancers
Groupe Oncologie Radiotherapie Tete et Cou
 2009-01 PHASE3
NCT02368899 COMPLETED
Alcoholism
Research Circle Associates, LLC
 2016-11
NCT02472548 COMPLETED
Respiratory Syncytial Virus
Dalhousie University
 2015-05 PHASE1
NCT02337855 COMPLETED
Schistosomiasis
National Institute of Allergy and Infectious Diseases (NIAID)
 2015-02-04 PHASE1
NCT04991194 TERMINATED
Pulmonary Arterial Hypertension
Bial - Portela C S.A.
 2015-10-12 PHASE1
NCT02720575 COMPLETED
Healthy
Boston University
 2016-01
NCT02930694 COMPLETED
Healthy
Janssen Research & Development, LLC
 2016-10 PHASE1
NCT01800175 UNKNOWN
Healthy Subjects
Ocular Therapeutix, Inc.
 2013-02 PHASE1
NCT01893606 UNKNOWN
Irritable Bowel Syndrome
Third Military Medical University
 2013-04 PHASE2; PHASE3
NCT02096133 TERMINATED
Multiple Sclerosis
Academic MS Center Limburg
 2014-10-13 PHASE2
NCT02513381 COMPLETED
Polycystic Ovary Syndrome
Hull University Teaching Hospitals NHS Trust
 2015-07
NCT02534636 COMPLETED
Healthy Subjects
Bristol-Myers Squibb
 2015-10 PHASE1
NCT01589666 COMPLETED
Coagulation Defects
Entegrion, Inc.
 2013-11 PHASE1
NCT02279914 COMPLETED
Abortion, Induced
Planned Parenthood of Greater New York
 2014-11
NCT02578420 COMPLETED
Placebo Effect; Pain; Expectancy
University Hospital, Basel, Switzerland
 2016-01
NCT02411903 UNKNOWN
Cerebral Infarction; Clopidogrel,Poor Metabolism of (Disorder)
The Third Affiliated Hospital of Guangzhou Medical University
 2015-03 PHASE4
NCT02545946 COMPLETED
Cutaneous Abscess
Wake Forest University Health Sciences
 2015-10
NCT04461665 COMPLETED
Vitamin D Deficiency
Shih Chien University
 2015-08-18
NCT02678416 COMPLETED
Pain
Mallinckrodt
 2015-12-07 PHASE4
NCT01669915 COMPLETED
Cognitive Decline
Brigham and Women's Hospital
 2011-09-14
NCT01649895 COMPLETED
Obsessive-compulsive Disorder
Christian Rück
 2012-08 PHASE4
NCT02437357 COMPLETED
Depression
Universitätsklinikum Hamburg-Eppendorf
 2015-03
NCT02275390 COMPLETED
Mental Illness
The Hong Kong Polytechnic University
 2012-03-01
NCT02530502 TERMINATED
Adult Glioblastoma
Northwestern University
 2015-09-30 PHASE1
NCT02768545 UNKNOWN
Hepatitis C
Pontificia Universidad Catolica de Chile
 2013-06 PHASE4
NCT02120274 TERMINATED
RNA Virus Infections; Flaviviridae Infections; Hepatitis C; Hepatitis C, Chronic
Federal University of São Paulo
 2014-03 PHASE4
NCT02569554 COMPLETED
Healthy
Pfizer
 2015-12 PHASE1
NCT01712724 COMPLETED
Cerebrovascular Accident
University Health Network, Toronto
 2013-03
NCT02678520 WITHDRAWN
Prostate Cancer
University of Kansas Medical Center
 2015-12 PHASE2
NCT00525785 COMPLETED
Stomach Cancer; Gastric Cancer
M.D. Anderson Cancer Center
 2004-01 PHASE2
NCT02406040 COMPLETED
Obesity
McMaster University
 2015-06
NCT02273154 UNKNOWN
Major Depression Disorder
Si Tianmei
 2014-08 PHASE4
NCT01987310 WITHDRAWN
Non Alcoholic Fatty Liver Disease
Sheba Medical Center
 2015-12
NCT01658410 UNKNOWN
Coronary Artery Disease; Aorto-coronary Bypass Grafting
Medical University of Vienna
 2012-07 PHASE2
NCT02349282 COMPLETED
Deficiency, Vitamin D; Elderly, Frail
Wageningen University
 2014-12
NCT02518763 UNKNOWN
Osteoporosis
University Hospital, Caen
 2011-06 PHASE3
NCT02120027 TERMINATED
Irritable Bowel Syndrome With Diarrhea
Menarini Group
 2014-02 PHASE3
NCT02026310 COMPLETED
Diabetes Mellitus, Type 2
Qifu Li
 2014-01
NCT02130817 WITHDRAWN
End Stage Renal Disease; Antibody Mediated Rejection
University of Wisconsin, Madison
 2014-09-24 PHASE4
NCT02452879 UNKNOWN
Overactive Bladder
Guang'anmen Hospital of China Academy of Chinese Medical Sciences
 2014-10
NCT02004548 COMPLETED
Advanced or Metastatic Solid Tumors
Jiangsu Simcere Pharmaceutical Co., Ltd.
 2013-05 PHASE1
NCT01633853 COMPLETED
Vitamin D Deficiency
Dongliang Zhang, MD
 2012-07 PHASE4
NCT01407848 COMPLETED
Transient Tachypnoea of the Newborn
University of Cologne
 2012-01 PHASE2
NCT00526110 COMPLETED
Gastrointestinal Diseases
M.D. Anderson Cancer Center
 2004-08 PHASE1; PHASE2
NCT01757847 COMPLETED
Binge-Eating Disorder
VA Office of Research and Development
 2013-01
NCT02331667 COMPLETED
Cognitive Performance
National Institute of Nutrition and Seafood Research, Norway
 2014-12
NCT02382640 COMPLETED
Healthy Volunteers
Takeda
 2015-03 PHASE1
NCT02221739 COMPLETED
Non-small Cell Lung Cancer (NSCLC)
NYU Langone Health
 2014-07-01 PHASE1; PHASE2
NCT01984801 COMPLETED
Acne Vulgaris
GlaxoSmithKline
 2013-10-14 PHASE1
NCT02751307 COMPLETED
Metabolic Syndrome
Taipei Medical University WanFang Hospital
 2013-05 PHASE4
NCT03521700 COMPLETED
Renal Artery Obstruction; Stents; Lipids; Glomerular Filtration Rate; Blood Pressure
Chinese Academy of Medical Sciences, Fuwai Hospital
 2013-06-01 PHASE2; PHASE3
NCT02218723 COMPLETED
Asthma
GlaxoSmithKline
 2014-10-28 PHASE1
NCT02142595 COMPLETED
Sleep Quality of Patients Undergoing TURP
China Medical University, China
 2014-05 PHASE4
NCT01455519 COMPLETED
Low Back Pain
Shirley Ryan AbilityLab
 2011-10 PHASE4
NCT02160756 COMPLETED
Healthy
Aragon Pharmaceuticals, Inc.
 2014-06 PHASE1
NCT01519635 COMPLETED
Hypertension
Centre Hospitalier Universitaire Vaudois
 2011-10 PHASE4
NCT01990885 COMPLETED
Celiac Disease
BioLineRx, Ltd.
 2013-12 PHASE1; PHASE2
NCT06689709 COMPLETED
Alkaline Phosphatase Deficiency; Vitamin D Deficiency
Emine Hafize
 2013-09-01
NCT01502202 UNKNOWN
Non Small Cell Lung Cancer; Adenocarcinoma
National Cancer Center, Korea
 2012-03 PHASE2
NCT03392961 COMPLETED
Type 2 Diabetes Mellitus
Biocon Limited
 2014-03-27 PHASE1
NCT01709474 TERMINATED
Systemic Lupus Erythematosus
National Institute of Allergy and Infectious Diseases (NIAID)
 2013-06 PHASE2
NCT00866307 COMPLETED
Acute Lymphoblastic Leukemia; Adult B Acute Lymphoblastic Leukemia; Childhood B Acute Lymphoblastic Leukemia
Children's Oncology Group
 2009-02-23 PHASE1
NCT00356278 COMPLETED
Stress Disorder, Post Traumatic
Emory University
 2006-09 PHASE2; PHASE3
NCT01071564 TERMINATED
Estrogen Receptor Negative; HER2/Neu Negative; Progesterone Receptor Negative; Recurrent Breast Carcinoma; Stage IIIB Breast Cancer; Stage IIIC Breast Cancer; Stage IV Breast Cancer; Triple-Negative Breast Carcinoma
National Cancer Institute (NCI)
 2009-11 PHASE1
NCT01608724 COMPLETED
Diabetes Mellitus, Non-Insulin-Dependent
AstraZeneca
 2012-11 PHASE4
NCT01905215 COMPLETED
Infections, Respiratory Syncytial Virus
GlaxoSmithKline
 2013-07-22 PHASE1
NCT02028598 COMPLETED
Healthy
CTC Bio, Inc.
 2014-01 PHASE1
NCT00632749 COMPLETED
Leukemia, Myeloid, Acute
Boehringer Ingelheim
 2008-05 PHASE2
NCT00103285 COMPLETED
Acute Lymphoblastic Leukemia; Childhood B Acute Lymphoblastic Leukemia
Children's Oncology Group
 2005-04-11 PHASE3
NCT00365937 TERMINATED
Melanoma
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
 2006-08 PHASE1; PHASE2
NCT01537809 COMPLETED
Vitamin D Deficiency
Tufts University
 2011-06
NCT02306798 COMPLETED
Ulcerative Colitis
Tillotts Pharma AG
 2013-09 PHASE1
NCT01157949 WITHDRAWN
Cardiac Allograft Vasculopathy
Cedars-Sinai Medical Center
 2010-11 PHASE3
NCT02092701 COMPLETED
Vitamin D; Burn Injury
University of Liege
 2012-10
NCT01363167 COMPLETED
Infant, Very Low Birth Weight; Calcium Deficiency; Vitamin D Deficiency
Medical University of South Carolina
 2011-10
NCT02055547 COMPLETED
Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC
 2013-05-10 PHASE1
NCT01316718 COMPLETED
Irritable Bowel Syndrome With Diarrhoea
University of Nottingham
 2011-03 PHASE4
NCT01593501 COMPLETED
Magnesium Deficiency; Calcium Metabolism Disorders
University of Wisconsin, Madison
 2012-05 PHASE4
NCT01856348 COMPLETED
Physiological Effects of Vitamin D
University of Zurich
 2013-05 PHASE1
NCT01709019 COMPLETED
Respiratory Syncytial Virus (RSV)
Novavax
 2012-10 PHASE1
NCT01056237 COMPLETED
Lupus Nephritis
Zhi-Hong Liu, M.D.
 2010-02
NCT01896492 COMPLETED
PCOS
Woman's Health University Hospital, Egypt
 2011-01 PHASE4
NCT01741324 COMPLETED
Vitamin D Deficiency
Umeå University
 2012-11
NCT01549002 COMPLETED
Abscess; Pain
Columbia University
 2012-01 PHASE3
NCT01805726 COMPLETED
Bronchoscopy; Conscious Sedation
Saint-Joseph University
 2013-02 PHASE3
NCT01350934 COMPLETED
Osteoporosis, Postmenopausal
Organon and Co
 2011-06-19 PHASE4
NCT01168401 COMPLETED
Gastroenteritis
Takeda
 2010-09-03 PHASE1
NCT01007071 COMPLETED
Hypopituitarism
Stanford University
 2009-11-01 PHASE3
NCT00696228 COMPLETED
Obesity
Vanderbilt University
 2008-08 PHASE3
NCT01447355 COMPLETED
Healthy, no Evidence of Disease; Skin Cancer
National Cancer Institute (NCI)
 2012-08 PHASE1
NCT01371058 COMPLETED
Coronary Artery Disease
Shenyang Northern Hospital
 2011-03 PHASE4
NCT01112891 COMPLETED
Vitamin D Deficiency
University of British Columbia
 2010-03 PHASE4
NCT01549236 COMPLETED
Chagas' Disease
Drugs for Neglected Diseases
 2011-05 PHASE4
NCT01634724 UNKNOWN
Infertile High-risk Patients With Polycystic Ovaries
Nanjing University
 2012-07
NCT00801606 COMPLETED
Tuberculosis
All India Institute of Medical Sciences
 2008-12 PHASE3
NCT01503216 COMPLETED
Vitamin D Deficiency
Ulrike Lehmann
 2012-01
NCT00154180 UNKNOWN
Menopause; Arteriosclerosis
Kronos Longevity Research Institute
 2005-09 PHASE4
NCT00748618 COMPLETED
Kidney Transplantation; Vitamin D Deficiency
University of Nebraska
 2008-10-01
NCT00926900 UNKNOWN
Alcohol Drinking
Central Institute of Mental Health, Mannheim
 2009-03 PHASE2; PHASE3
NCT01919905 COMPLETED
Change in Serum 25 Hydroxyvitamin D Levels
University of Toronto
 2012-01
NCT01101113 COMPLETED
Secondary Hyperparathyroidism
Seoul National University Hospital
 2010-09 PHASE4
NCT01008384 COMPLETED
Atherosclerosis
Rockefeller University
 2009-10
NCT00482846 COMPLETED
Mucositis; Multiple Myeloma
Barbara Ann Karmanos Cancer Institute
 2007-06 PHASE1
NCT01309477 COMPLETED
Nephrotic Syndrome
Sun Yat-sen University
 2011-01 PHASE3
NCT01208688 COMPLETED
Spinal Cord Injuries
Toronto Rehabilitation Institute
 2009-09 PHASE2
NCT01263028 TERMINATED
Chronic Kidney Disease Stages 3-5
Kaiser Permanente
 2010-08
NCT01524874 COMPLETED
Hypovitaminosis D; Insulin Resistance; Diabetes
Bastyr University
 2010-08
NCT01268618 TERMINATED
IBS-D and Functional Dyspepsia
Sprim Advanced Life Sciences
 2011-01 PHASE2; PHASE3
NCT00398710 COMPLETED
Waldenström's Macroglobulinemia
AEterna Zentaris
 2006-10 PHASE2
NCT01100723 COMPLETED
Secondary Hyperparathyroidism; Chronic Kidney Disease
University of Colorado, Denver
 2010-03 PHASE4
NCT01218880 UNKNOWN
Pancreatic Cancer
Beijing Protgen Biotechnology Development Co., Ltd.
 2010-06 PHASE1
NCT00118066 TERMINATED
Precancerous/Nonmalignant Condition; Prostate Cancer
Rutgers, The State University of New Jersey
 2004-05 PHASE2
NCT01347203 COMPLETED
Deep Vein Thrombosis Leg
Diakron Pharmaceuticals
 2011-04 PHASE1
NCT01310478 UNKNOWN
Colorectal Neoplasm
Fudan University
 2010-08 PHASE1
NCT00495326 COMPLETED
Tuberculosis; Aids; Hiv Infections
French National Agency for Research on AIDS and Viral Hepatitis
 2007-12 PHASE2; PHASE3
NCT01402648 COMPLETED
Adenocarcinoma of Colon Recurrent
CM&D Pharma Limited
 2009-10 PHASE1; PHASE2
NCT00870220 TERMINATED
Turner's Syndrome
University of Chicago
 2009-04 PHASE1
NCT03409510 COMPLETED
Healthy Volunteers
Bispebjerg Hospital
 2010-11-01
NCT00994396 COMPLETED
Obesity; Glucose Intolerance; Inflammation
University of Missouri-Columbia
 2009-11
NCT01181700 COMPLETED
Pharmacokinetics
Pfizer
 2010-10 PHASE1
NCT01213511 COMPLETED
Coronary Artery Bypass
AHEPA University Hospital
 2009-01
NCT00315133 COMPLETED
Type 1 Diabetes Mellitus
University of Sao Paulo
 2003-12 PHASE1; PHASE2
NCT00634595 UNKNOWN
Head and Neck Squamous Carcinoma; Nasopharyngeal Carcinoma
Sun Yat-sen University
 2008-03 PHASE2
NCT01075022 UNKNOWN
Insulin Resistance; Glucose Intolerance
Hospital de Clinicas de Porto Alegre
 2009-05
NCT00524589 TERMINATED
Prostate Cancer
Roswell Park Cancer Institute
 2006-04 PHASE2
NCT00513058 COMPLETED
Breast Cancer
UNICANCER
 2007-06 PHASE1
NCT01095601 COMPLETED
Healthy
VIVUS LLC
 2010-04 PHASE1
NCT00985361 COMPLETED
Type 2 Diabetes Mellitus
ProMedica Health System
 2009-10
NCT00677339 COMPLETED
Smear Positive Pulmonary Tuberculosis
Menzies School of Health Research
 2008-06 PHASE3
NCT00433381 COMPLETED
Adult Glioblastoma; Adult Gliosarcoma; Recurrent Adult Brain Neoplasm
National Cancer Institute (NCI)
 2007-03-01 PHASE2
NCT00207402 COMPLETED
Hepatitis C
Brooke Army Medical Center
 2005-10 PHASE4
NCT00608660 COMPLETED
Bell's Palsy
Chengdu University of Traditional Chinese Medicine
 2006-10
NCT00663104 TERMINATED
Bone Diseases; Metabolic Syndrome X; Coronary Disease
University of Erlangen-Nürnberg Medical School
 2008-04 PHASE3
NCT00664430 TERMINATED
Secondary Hyperparathyroidism; Dialysis
Abbott
 2009-01 PHASE4
NCT01042197 COMPLETED
Vitamin D Status
Bispebjerg Hospital
 2008-01
NCT00558961 TERMINATED
Chronic Lymphocytic Leukemia
Jewish General Hospital
 2005-10 PHASE1; PHASE2
NCT01547377 COMPLETED
Dietary Selenium Deficiency; Dietary Zinc Deficiency
Universidade Federal do Rio Grande do Norte
 2008-01
NCT00850746 COMPLETED
Functional Dyspepsia
Astellas Pharma Inc
 2009-02 PHASE1
NCT00771199 COMPLETED
Cancer, Pain
Janssen-Cilag Ltd.
 2008-10-01 PHASE4
NCT00086411 COMPLETED
Tobacco Use Disorder
University of Pennsylvania
 2003-09 PHASE2
NCT00442598 TERMINATED
Ovarian Cancer
Eleison Pharmaceuticals LLC.
 2007-01 PHASE2
NCT00718653 COMPLETED
Eye Health
National Eye Institute (NEI)
 2004-09
NCT00337987 COMPLETED
Peripheral T-Cell Lymphoma
Yale University
 2005-11 PHASE2
NCT00769132 COMPLETED
Hypercholesterolemia
Merck Sharp & Dohme LLC
 2007-08-03 PHASE1
NCT01181310 COMPLETED
Dementia
Merck Sharp & Dohme LLC
 2007-06 PHASE1
NCT00456339 TERMINATED
Obstructive Sleep Apnea Syndrome
University of Chicago
 2006-07 PHASE4
NCT00009789 COMPLETED
Lung Cancer
Alliance for Clinical Trials in Oncology
 2000-12 PHASE1
NCT00301080 TERMINATED
Neurotoxicity; Pain; Breast Cancer
Northwestern University
 2006-02 PHASE3
NCT00203957 COMPLETED
Parkinson's Disease
University of Chicago
 2005-03 PHASE3
NCT00307710 COMPLETED
Lymphoma
M.D. Anderson Cancer Center
 2004-08 PHASE2
NCT00586014 COMPLETED
Multiple Myeloma
Duke University
 1997-05 PHASE2
NCT00227110 COMPLETED
Nonalcoholic Steatohepatitis
The University of Texas Health Science Center at San Antonio
 2002-10 PHASE4
NCT01371175 COMPLETED
HIV Infections
International AIDS Vaccine Initiative
 2003-04 PHASE2
NCT00769418 COMPLETED
Osteoporosis
Merck Sharp & Dohme LLC
 2004-09 PHASE1
NCT01819649 COMPLETED
Cancer
Odense University Hospital
 1998-11
NCT00615238 COMPLETED
Obesity
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
 2000-04
NCT02183012 COMPLETED
Healthy
Boehringer Ingelheim
 2002-08 PHASE1
NCT01437826 TERMINATED
Colorectal Adenomas
IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
 1988-03 PHASE3
NCT00353093 COMPLETED
Deep Vein Thrombosis of the Lower Extremities
University of Padova
 2003-01
NCT00235586 COMPLETED
Postmenopausal Women
University of Kansas
 2004-04
NCT00460460 TERMINATED
Lymphoma
AstraZeneca
 2007-03 PHASE1
NCT01168544 COMPLETED
Vitamin D Deficiency in Older Persons
Rijnstate Hospital
 2011-05 PHASE3
NCT01215890 COMPLETED
Crohn's Disease; Low Bone Mineral Density
University of Alberta
 PHASE4
NCT00567086 COMPLETED
Migraine
TorreyPines Therapeutics
 2006-10 PHASE2
NCT00160264 COMPLETED
Osteopenia
Solvay Pharmaceuticals
 2003-01 PHASE4

(data from https://clinicaltrials.gov, updated on 2026-03-27)

Check the D-(+)-Trehalose dihydrate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Compliance for Clinical Use

Mechanism and Biochemical Profile

As a non-reducing disaccharide, D-(+)-trehalose directly stabilizes cellular membranes and protein structures, preventing aberrant protein aggregation and suppressing downstream intracellular stress signaling pathways. This preservation of cellular integrity and enhancement of autophagic clearance reduces biomolecular damage, conferring cytoprotection relevant to clinical studies in metabolic disorders and solid tumors.

Appendix RUO and cGMP Quality Standards

Quality Dimension RUO (Research Use Only) cGMP (Current Good Manufacturing Practice)
Clinical Applicability Prohibited in human clinical trials or medical diagnostics. Mandatory for human clinical trials (Phase I–III) and therapies.
Regulatory Status Non-regulated grade; exempt from drug manufacturing laws. Legally enforced by health authorities (e.g., FDA, EMA, NMPA).
Facility Environment Unclassified analytical or research laboratories. Validated Cleanrooms (ISO Class 5–8) with continuous monitoring.
Quality Control Basic purity and activity testing. Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma).
Process Validation Basic equipment calibration; no process validation required. Full qualification (IQ/OQ/PQ) and complete batch records.
Quality Assurance Vendor self-declared without required formal QMS. Mandatory QA/QC unit, Change Control, CAPA, and vendor audits.
Regulatory Impact High risk of IND rejection if used as a critical raw material. Required for IND/NDA filings, supported by Drug Master Files (DMF).

Footnotes

Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).

Jump to

Note: Technical data last updated: Sep 1, 2026.