CAS No. 30964-13-7
Batch:
Purity:99.97
Chemical Structure
Check the
Cynarin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | (1R,3R,4S,5R)-1,3-bis[3-(3,4-dihydroxyphenyl)prop-2-enoyloxy]-4,5-dihydroxycyclohexane-1-carboxylic acid | |
|---|---|---|
| CAS Number | 30964-13-7 | |
| Molecular Formula |
C25H24O12 |
|
| Molecular Weight (MW) | 516.45 | |
| InChIKey | YDDUMTOHNYZQPO-GCBRTHAASA-N |
Biological Activity
Cynarin is an artichoke-derived phytochemical that acts as an antioxidant and inhibitor of the T-cell co-stimulatory pathway by blocking the interaction between CD28 on T cells and CD80 on antigen-presenting cells. It promotes the nuclear translocation of Nrf2, restoring the balance between glutathione and reactive oxygen species while preventing mitochondrial depolarization. Through these mechanisms, cynarin exhibits free-radical scavenging, antiviral, and immunomodulatory activities. [1][2]
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(193.62 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 3 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
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Note: Technical data last updated: Sep 1, 2026.