Home Microbiology Parasite inhibitor Pyrantel Pamoate For research use only.

Pyrantel Pamoate

Synonyms: Pyrantel Embonate

Pyrantel pamoate (Pyrantel Embonate), a broad-spectrum anthelmintic drug, is used to treat a number of parasitic worm infections.

Pyrantel Pamoate Chemical Structure

Pyrantel Pamoate Chemical Structure

CAS: 22204-24-6

Purity & Quality Control

Batch: S250101 DMSO] 100 mg/mL] false] Water] Insoluble] false] Ethanol] Insoluble] false Purity: 99.99%
99.99

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Biological Activity

Description Pyrantel pamoate (Pyrantel Embonate), a broad-spectrum anthelmintic drug, is used to treat a number of parasitic worm infections.
In vitro
In vitro Pyrantel pamoate can be used to treat helminthic infections (pinworm, hookworm, and others) because it blocks the neuromuscular junction and, consequently, blocks worm movements (the parasite is then expelled by the peristaltic movements). Its pharmacological action involves inhibition of cholinesterases[1].

Chemical Information & Solubility

Molecular Weight 594.692 Formula

C23H16O6.C11H14N2S
CAS No. 22204-24-6 SDF Download Pyrantel Pamoate SDF
Smiles CN1CCCN=C1C=CC2=CC=CS2.C1=CC=C2C(=C1)C=C(C(=C2CC3=C(C(=CC4=CC=CC=C43)C(=O)O)O)O)C(=O)O
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 100 mg/mL ( (168.15 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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