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Pyrantel Pamoate Parasite inhibitor

Cat.No.S2501

Pyrantel pamoate (Pyrantel Embonate), a broad-spectrum anthelmintic drug, is used to treat a number of parasitic worm infections.
Pyrantel Pamoate Parasite inhibitor Chemical Structure

Chemical Structure

Molecular Weight: 594.692

Jump to Mechanism of Action Solubility Chemical Information, Storage & Stability

Quality Control

Batch: S250101 DMSO]100 mg/mL]false]Water]Insoluble]false]Ethanol]Insoluble]false Purity: 99.99%
99.99

Chemical Information, Storage & Stability

Molecular Weight 594.692 Formula

C23H16O6.C11H14N2S

 Storage (From the date of receipt)
CAS No. 22204-24-6 Download SDF Storage of Stock Solutions

Synonyms Pyrantel Embonate Smiles CN1CCCN=C1C=CC2=CC=CS2.C1=CC=C2C(=C1)C=C(C(=C2CC3=C(C(=CC4=CC=CC=C43)C(=O)O)O)O)C(=O)O

Solubility

In vitro
Batch:

DMSO : 100 mg/mL (168.15 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : Insoluble

Ethanol : Insoluble

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

In vitro
Pyrantel pamoate can be used to treat helminthic infections (pinworm, hookworm, and others) because it blocks the neuromuscular junction and, consequently, blocks worm movements (the parasite is then expelled by the peristaltic movements). Its pharmacological action involves inhibition of cholinesterases[1].
References

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