4'-Methoxyresveratrol

Catalog No.S3939

For research use only.

4-Methoxyresveratrol is a stibenoid found in the Chinese herb Gnetum cleistostachyum. 4'-Methoxyresveratrol alleviates AGE-induced inflammation through suppressing RAGE-mediated MAPK/NF-κB signaling pathway and NLRP3 inflammasome activation.

4'-Methoxyresveratrol Chemical Structure

CAS No. 33626-08-3

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Biological Activity

Description 4-Methoxyresveratrol is a stibenoid found in the Chinese herb Gnetum cleistostachyum. 4'-Methoxyresveratrol alleviates AGE-induced inflammation through suppressing RAGE-mediated MAPK/NF-κB signaling pathway and NLRP3 inflammasome activation.
Targets
NF-κB [1]
()
NLRP3 [1]
()

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 48 mg/mL
(198.12 mM)
Ethanol 48 mg/mL
(198.12 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 242.27
Formula

C15H14O3

CAS No. 33626-08-3
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles COC1=CC=C(C=C1)C=CC2=CC(=CC(=C2)O)O

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT01199250 Not yet recruiting Other: Laboratory Biomarker Analysis Lynch Syndrome|Recurrent Uterine Corpus Carcinoma|Stage I Uterine Corpus Cancer|Stage II Uterine Corpus Cancer|Stage III Uterine Corpus Cancer|Stage IV Uterine Corpus Cancer Gynecologic Oncology Group|National Cancer Institute (NCI)|GOG Foundation January 2100 --
NCT02861183 Not yet recruiting Device: OVT (Sodium Hyaluronate)|Device: Saline Epicondylitis|Tennis Elbow|Epicondylosis Anika Therapeutics Inc. September 2025 Not Applicable
NCT02442752 Withdrawn Drug: Dexlansoprazole Pediatric Gastroesophageal Reflux Disease Takeda June 15 2025 Phase 1
NCT03773328 Not yet recruiting Biological: CK0801 Guillain-Barré Syndrome Cellenkos Inc. November 2022 Phase 1
NCT04134026 Not yet recruiting Drug: HIF-PHI|Drug: Epoetin Alfa Anemia in Incident Dialysis Patients Second Xiangya Hospital of Central South University October 20 2022 Phase 4
NCT04887935 Not yet recruiting Drug: Dapagliflozin Prostate Cancer|Cancer of Prostate Washington University School of Medicine September 30 2022 Phase 1

(data from https://clinicaltrials.gov, updated on 2021-09-06)

Tech Support

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Handling Instructions

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