CAS No. 33626-08-3
| IUPAC Name | 5-[(E)-2-(4-methoxyphenyl)ethenyl]benzene-1,3-diol | |
|---|---|---|
| CAS Number | 33626-08-3 | |
| Molecular Formula |
C15H14O3 |
|
| Molecular Weight (MW) | 242.27 | |
| SMILES | COC1=CC=C(C=C1)C=CC2=CC(=CC(=C2)O)O | |
| InChIKey | IHVRWFJGOIWMGC-NSCUHMNNSA-N |
4'-Methoxyresveratrol is a naturally occurring stilbenoid isolated from Gnetum cleistostachyum that exhibits anti-inflammatory activity. It suppresses advanced glycation end-product (AGE)-induced cellular inflammatory responses by blocking RAGE-mediated signaling cascades. This inhibition attenuates downstream MAPK and NF-κB signaling pathways, leading to reduced activation of the NLRP3 inflammasome and suppression of proinflammatory mediator expression. [1]
|
Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| DMSO |
48 mg/mL
(198.12 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 48 mg/mL |
| Water | Insoluble |
| DMSO |
48 mg/mL
(198.12 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 48 mg/mL |
| Water | Insoluble |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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- 4'-Methoxyresveratrol SDS｜MSDS