IL Receptor

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IL Receptor Products

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IL Receptor Inhibitors (3)
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New IL Receptor Products

Catalog No.	Product Name	Information	Product Use Citations
S4028	Dexamethasone Sodium Phosphate	Dexamethasone (Dexamethasone 21-phosphate disodium salt) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects.	Cell Rep, 2021, 36(2):109360 Mol Cancer, 2021, 20(1):84 JCI Insight, 2021, 6(19)e147038
S5764	YM 90709	YM 90709 is a novel IL-5 inhibitor which selectively blocks the binding of IL-5 to the IL-5 receptor (IL-5R).
S8562	IRAK4-IN-2	IRAK4-IN-2 is a reversible kinase inhibitor that modulates IRAK4 function in both the toll-like receptor (TLR) and interleukin 1 receptor (IL-1R) signaling cascades.	Cancer Lett, 2021, 503:75-90 Cancer Lett, 2021, 503:75-90
A2011	Sarilumab (anti-IL-6Rα)	Sarilumab (anti-IL-6Rα) is a fully human anti-IL-6Rα mAb that binds membrane-bound and soluble human IL-6Rα with high affinity, MW: 144.13 KD.	Cancer Lett, 2022, 524:161-171 Xenotransplantation, 2019, doi: 10
A2012	Tocilizumab (anti-IL-6R)	Tocilizumab (anti-IL-6R) is a humanized monoclonal antibody that binds to the interleukin-6 receptor, MW: 148 KD.	Cancer Lett, 2022, 524:161-171 Nat Commun, 2021, 12(1):5006 Adv Healthc Mater, 2021, e2100884
S1322	Dexamethasone (MK-125)	Dexamethasone (MK-125, NSC 34521, Hexadecadrol, Prednisolone F) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects. Dexamethasone induces autophagy and mitophagy. Dexamethasone is tested in hospitalized patients with COVID-19 and is found to have benefits for critically ill patients.	Mol Syst Biol, 2021, 17(9):e10426 Cell Rep, 2021, 36(2):109360 Cell Rep, 2021, 37(5):109912
S3124	Dexamethasone Acetate	Dexamethasone (NSC 39471) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects.	Cell Rep, 2021, 36(2):109360 J Control Release, 2021, S0168-3659(21)00446-6 Mol Cancer, 2021, 20(1):84
S4028	Dexamethasone Sodium Phosphate	Dexamethasone (Dexamethasone 21-phosphate disodium salt) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects.	Cell Rep, 2021, 36(2):109360 Mol Cancer, 2021, 20(1):84 JCI Insight, 2021, 6(19)e147038
S5764	YM 90709	YM 90709 is a novel IL-5 inhibitor which selectively blocks the binding of IL-5 to the IL-5 receptor (IL-5R).
S8562	IRAK4-IN-2	IRAK4-IN-2 is a reversible kinase inhibitor that modulates IRAK4 function in both the toll-like receptor (TLR) and interleukin 1 receptor (IL-1R) signaling cascades.	Cancer Lett, 2021, 503:75-90 Cancer Lett, 2021, 503:75-90
A2011	Sarilumab (anti-IL-6Rα)	Sarilumab (anti-IL-6Rα) is a fully human anti-IL-6Rα mAb that binds membrane-bound and soluble human IL-6Rα with high affinity, MW: 144.13 KD.	Cancer Lett, 2022, 524:161-171 Xenotransplantation, 2019, doi: 10
A2012	Tocilizumab (anti-IL-6R)	Tocilizumab (anti-IL-6R) is a humanized monoclonal antibody that binds to the interleukin-6 receptor, MW: 148 KD.	Cancer Lett, 2022, 524:161-171 Nat Commun, 2021, 12(1):5006 Adv Healthc Mater, 2021, e2100884
S1322	Dexamethasone (MK-125)	Dexamethasone (MK-125, NSC 34521, Hexadecadrol, Prednisolone F) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects. Dexamethasone induces autophagy and mitophagy. Dexamethasone is tested in hospitalized patients with COVID-19 and is found to have benefits for critically ill patients.	Mol Syst Biol, 2021, 17(9):e10426 Cell Rep, 2021, 36(2):109360 Cell Rep, 2021, 37(5):109912
S3124	Dexamethasone Acetate	Dexamethasone (NSC 39471) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects.	Cell Rep, 2021, 36(2):109360 J Control Release, 2021, S0168-3659(21)00446-6 Mol Cancer, 2021, 20(1):84