IL Receptor

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IL Receptor Products

All (8)
IL Receptor Inhibitors (5)
IL Receptor Modulators (2)
New IL Receptor Products

Catalog No.	Product Name	Information	Product Use Citations
A2011	Sarilumab (anti-IL-6Rα)	Sarilumab (anti-IL-6Rα) is a fully human anti-IL-6Rα mAb that binds membrane-bound and soluble human IL-6Rα with high affinity, MW: 144.13 KD.	Cancer Lett, 2022, 524:161-171 Xenotransplantation, 2019, doi: 10
A2012	Tocilizumab (anti-IL-6R)	Tocilizumab (anti-IL-6R) is a humanized monoclonal antibody that binds to the interleukin-6 receptor, MW: 148 KD.	Signal Transduct Target Ther, 2022, 7(1):52 Haematologica, 2022, 10.3324/haematol.2021.279957 Front Immunol, 2022, 13:832989
S4028	Dexamethasone Sodium Phosphate	Dexamethasone (Dexamethasone 21-phosphate disodium salt) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects.	Pharmaceutics, 2022, 14(2)400 Dis Model Mech, 2022, dmm.049109 Hematology, 2022, 27(1):32-42
S5764	YM 90709	YM 90709 is a novel IL-5 inhibitor which selectively blocks the binding of IL-5 to the IL-5 receptor (IL-5R).
S8562	IRAK4-IN-2	IRAK4-IN-2 is a reversible kinase inhibitor that modulates IRAK4 function in both the toll-like receptor (TLR) and interleukin 1 receptor (IL-1R) signaling cascades.	Cancer Lett, 2021, 503:75-90 Cancer Lett, 2021, 503:75-90
S1322	Dexamethasone (MK-125)	Dexamethasone (MK-125, NSC 34521, Hexadecadrol, Prednisolone F) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects. Dexamethasone induces autophagy and mitophagy. Dexamethasone is tested in hospitalized patients with COVID-19 and is found to have benefits for critically ill patients.	Cell Stem Cell, 2022, 29(4):545-558.e13 Blood, 2022, blood.2022016241 Hepatology, 2022, 10.1002/hep.32436
S3124	Dexamethasone Acetate	Dexamethasone (NSC 39471) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects.	Pharmaceutics, 2022, 14(2)400 Hematology, 2022, 27(1):32-42 Cell Rep, 2021, 36(2):109360
S0725	RP-54745	RP-54745 inhibits macrophage stimulation and interleukin-1 production. RP-54745 is a potential antirheumatic compound.
A2011	Sarilumab (anti-IL-6Rα)	Sarilumab (anti-IL-6Rα) is a fully human anti-IL-6Rα mAb that binds membrane-bound and soluble human IL-6Rα with high affinity, MW: 144.13 KD.	Cancer Lett, 2022, 524:161-171 Xenotransplantation, 2019, doi: 10
A2012	Tocilizumab (anti-IL-6R)	Tocilizumab (anti-IL-6R) is a humanized monoclonal antibody that binds to the interleukin-6 receptor, MW: 148 KD.	Signal Transduct Target Ther, 2022, 7(1):52 Haematologica, 2022, 10.3324/haematol.2021.279957 Front Immunol, 2022, 13:832989
S4028	Dexamethasone Sodium Phosphate	Dexamethasone (Dexamethasone 21-phosphate disodium salt) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects.	Pharmaceutics, 2022, 14(2)400 Dis Model Mech, 2022, dmm.049109 Hematology, 2022, 27(1):32-42
S5764	YM 90709	YM 90709 is a novel IL-5 inhibitor which selectively blocks the binding of IL-5 to the IL-5 receptor (IL-5R).
S8562	IRAK4-IN-2	IRAK4-IN-2 is a reversible kinase inhibitor that modulates IRAK4 function in both the toll-like receptor (TLR) and interleukin 1 receptor (IL-1R) signaling cascades.	Cancer Lett, 2021, 503:75-90 Cancer Lett, 2021, 503:75-90
S1322	Dexamethasone (MK-125)	Dexamethasone (MK-125, NSC 34521, Hexadecadrol, Prednisolone F) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects. Dexamethasone induces autophagy and mitophagy. Dexamethasone is tested in hospitalized patients with COVID-19 and is found to have benefits for critically ill patients.	Cell Stem Cell, 2022, 29(4):545-558.e13 Blood, 2022, blood.2022016241 Hepatology, 2022, 10.1002/hep.32436
S3124	Dexamethasone Acetate	Dexamethasone (NSC 39471) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects.	Pharmaceutics, 2022, 14(2)400 Hematology, 2022, 27(1):32-42 Cell Rep, 2021, 36(2):109360