IL Receptor

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IL Receptor Products

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  • IL Receptor Inhibitors (5)
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Catalog No. Product Name Information Product Use Citations Product Validations
A2011 Sarilumab (anti-IL-6Rα) Sarilumab (anti-IL-6Rα) is a fully human anti-IL-6Rα mAb that binds membrane-bound and soluble human IL-6Rα with high affinity, MW: 144.13 KD.
Cancer Lett, 2022, 524:161-171
Xenotransplantation, 2019, doi: 10
A2012 Tocilizumab (anti-IL-6R) Tocilizumab (anti-IL-6R) is a humanized monoclonal antibody that binds to the interleukin-6 receptor, MW: 148 KD.
Signal Transduct Target Ther, 2022, 7(1):52
Haematologica, 2022, 10.3324/haematol.2021.279957
Front Immunol, 2022, 13:832989
S4028 Dexamethasone Sodium Phosphate Dexamethasone (Dexamethasone 21-phosphate disodium salt) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects.
Pharmaceutics, 2022, 14(2)400
Dis Model Mech, 2022, dmm.049109
Hematology, 2022, 27(1):32-42
S5764 YM 90709 YM 90709 is a novel IL-5 inhibitor which selectively blocks the binding of IL-5 to the IL-5 receptor (IL-5R).
S8562 IRAK4-IN-2 IRAK4-IN-2 is a reversible kinase inhibitor that modulates IRAK4 function in both the toll-like receptor (TLR) and interleukin 1 receptor (IL-1R) signaling cascades.
Cancer Lett, 2021, 503:75-90
Cancer Lett, 2021, 503:75-90
S1322 Dexamethasone (MK-125) Dexamethasone (MK-125, NSC 34521, Hexadecadrol, Prednisolone F) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects. Dexamethasone induces autophagy and mitophagy. Dexamethasone is tested in hospitalized patients with COVID-19 and is found to have benefits for critically ill patients.
Cell Stem Cell, 2022, 29(4):545-558.e13
Blood, 2022, blood.2022016241
Hepatology, 2022, 10.1002/hep.32436
S3124 Dexamethasone Acetate Dexamethasone (NSC 39471) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects.
Pharmaceutics, 2022, 14(2)400
Hematology, 2022, 27(1):32-42
Cell Rep, 2021, 36(2):109360
S0725 RP-54745 RP-54745 inhibits macrophage stimulation and interleukin-1 production. RP-54745 is a potential antirheumatic compound.
A2011 Sarilumab (anti-IL-6Rα) Sarilumab (anti-IL-6Rα) is a fully human anti-IL-6Rα mAb that binds membrane-bound and soluble human IL-6Rα with high affinity, MW: 144.13 KD.
Cancer Lett, 2022, 524:161-171
Xenotransplantation, 2019, doi: 10
A2012 Tocilizumab (anti-IL-6R) Tocilizumab (anti-IL-6R) is a humanized monoclonal antibody that binds to the interleukin-6 receptor, MW: 148 KD.
Signal Transduct Target Ther, 2022, 7(1):52
Haematologica, 2022, 10.3324/haematol.2021.279957
Front Immunol, 2022, 13:832989
S4028 Dexamethasone Sodium Phosphate Dexamethasone (Dexamethasone 21-phosphate disodium salt) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects.
Pharmaceutics, 2022, 14(2)400
Dis Model Mech, 2022, dmm.049109
Hematology, 2022, 27(1):32-42
S5764 YM 90709 YM 90709 is a novel IL-5 inhibitor which selectively blocks the binding of IL-5 to the IL-5 receptor (IL-5R).
S8562 IRAK4-IN-2 IRAK4-IN-2 is a reversible kinase inhibitor that modulates IRAK4 function in both the toll-like receptor (TLR) and interleukin 1 receptor (IL-1R) signaling cascades.
Cancer Lett, 2021, 503:75-90
Cancer Lett, 2021, 503:75-90
S1322 Dexamethasone (MK-125) Dexamethasone (MK-125, NSC 34521, Hexadecadrol, Prednisolone F) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects. Dexamethasone induces autophagy and mitophagy. Dexamethasone is tested in hospitalized patients with COVID-19 and is found to have benefits for critically ill patients.
Cell Stem Cell, 2022, 29(4):545-558.e13
Blood, 2022, blood.2022016241
Hepatology, 2022, 10.1002/hep.32436
S3124 Dexamethasone Acetate Dexamethasone (NSC 39471) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects.
Pharmaceutics, 2022, 14(2)400
Hematology, 2022, 27(1):32-42
Cell Rep, 2021, 36(2):109360
Tags: IL Receptor inhibitor|IL Receptor agonist|IL Receptor activator|IL Receptor inducer|IL Receptor antagonist|IL Receptor signaling pathway|IL Receptor assay kit