Influenza Virus

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Influenza Virus Products

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  • Influenza Virus Inhibitors (17)
  • New Influenza Virus Products
Catalog No. Product Name Information Product Use Citations Product Validations
E0207New Chebulinic acid

Chebulinic acid, a phenolic compound isolated from Terminalia chebula fruit, is a novel Influenza viral neuraminidase inhibitor. Chebulinic acid is a antiangiogenic agent through inhibiting the actions of VEGF. Chebulinic acid shows antitumour activity.

S0289 KIN1148 KIN1148 is an agonist of interferon regulatory factor 3 (IRF3) that induces dose-dependent IRF3 nuclear translocation and specific activation of IRF3-responsive promoters. KIN1148 is an influenza vaccine adjuvant that enhances flu vaccine efficacy.
S0433 Nucleozin Nucleozin is an antivirus agent that targets influenza A nucleoprotein (NP). Nucleozin triggers the aggregation of NP and inhibits its nuclear accumulation.
Nat Commun, 2022, 13(1):2079
S0861 Laninamivir Octanoate Laninamivir octanoate (CS-8958, R-118958, Inavir, LANI), a prodrug of Laninamivir (R-125489), is a long-acting neuraminidase (NA) inhibitor with superior anti-influenza virus activity.
S1627 Nitazoxanide (NSC 697855) Nitazoxanide (NTZ, NSC 697855) is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent(IC50 for canine influenza virus ranges from 0.17 to 0.21 μM). Nitazoxanide modulates autophagy and inhibits mTORC1 signaling.
Biochem Pharmacol, 2022, 197:114913
Oncol Lett, 2022, 23(4):123
Front Pharmacol, 2021, 12:781640
S1848 Curcumin Curcumin (Diferuloylmethane, Natural Yellow 3, Turmeric yellow) is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). It is an inhibitor of p300 histone acetylatransferase(IC50~25 μM)and Histone deacetylase (HDAC); activates Nrf2 pathway and supresses the activation of NF-κB. Curcumin induces mitophagy, autophagy, apoptosis, and cell cycle arrest with antitumor activity. Curcumin reduces renal damage associated with rhabdomyolysis by decreasing ferroptosis-mediated cell death. Curcumin exhibits anti-infective properties against various human pathogens like the influenza virus, hepatitis C virus, HIV and so on.
Phytother Res, 2022, 36(3):1326-1337
Dis Markers, 2022, 2022:3129781
Adv Sci (Weinh), 2021, e2103360
S1964 Rimantadine Rimantadine (Flumadine) is an anti-influenza virus drug for T. brucei with IC50 of 7 μM.
J Virol Methods, 2019, 274:113714
S2120 Arbidol HCl Arbidol HCl (Umifenovir) is a broad-spectrum antiviral compound that blocks viral fusion, used in treatment of influenza and other respiratory viral infections.
S2597 Oseltamivir Phosphate Oseltamivir Phosphate is a potent and selective inhibitor of the neuraminidase that is essential for replication of influenza A and B viruses, used to prevent influenza.
iScience, 2022, 25(4):104088
J Ethnopharmacol, 2021, S0378-8741(21)00290-7
J Cell Mol Med, 2018, 22(3):1826-1839
S2716 Peramivir Trihydrate Peramivir Trihydrate (BCX-1812, RWJ-270201, S-021812) is a trihydrate of the anti-infection agent peramivir which is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM.
Emerg Microbes Infec, 2014, 3, e78
Emerg Microbes Infect, 2014, 3(11):e78
S2869 Adamantane

Adamantane is a colorless, crystalline chemical compound first isolated from petroleum with a camphor-like odor. Adamantane is used to treat influenza A virus infections.

S3007 Zanamivir Zanamivir (GG167) is a neuraminidase inhibitor used in the treatment and prophylaxis of influenza caused by influenza A virus and influenza B virus.
Front Immunol, 2019, 10:2575
Emerg Microbes Infec, 2014, 3, e78
Emerg Microbes Infect, 2014, 3(11):e78
S4491 Cetylpyridinium chloride monohydrate Cetylpyridinium chloride (CPC, Hexadecylpyridinium chloride) monohydrate is a broad-spectrum antimicrobial agent that possesses virucidal activity against susceptible and resistant strains of influenza virus by targeting and disrupting the viral envelope.
S5499 Amantadine Amantadine (1-Adamantanamine, 1-Adamantylamine, 1-Aminoadamantane) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is an M2 inhibitor which blocks the ion channel formed by the M2 protein that spans the viral membrane.
S6854 Triazavirin Triazavirin (TZV, Riamilovir) is a novel antiviral drug, a nucleoside analogue of nucleic acid that inhibits the synthesis of viral RNA and DNA and replication of genomic fragments. Triazavirin is active against influenza and a number of other viruses. Triazavirin is an effective protective agent on the transmission stage of influenza.
S7273 SC75741 SC75741 is a potent NF-κB inhibitor with EC50 of 200 nM. SC75741 efficiently blocks influenza virus propagation.
Front Immunol, 2022, 13:839460
Int J Mol Sci, 2022, 23(6)3280
Microbiol Spectr, 2022, e0188121
S7975 Favipiravir (T-705) Favipiravir (T-705) is a potent and selective RNA-dependent RNA polymerase inhibitor, used to treat influenza virus infections.
Nat Commun, 2022, 13(1):2256
Antiviral Res, 2022, 199:105273
Rapid Commun Mass Spectrom, 2022, e9255
E0207New Chebulinic acid

Chebulinic acid, a phenolic compound isolated from Terminalia chebula fruit, is a novel Influenza viral neuraminidase inhibitor. Chebulinic acid is a antiangiogenic agent through inhibiting the actions of VEGF. Chebulinic acid shows antitumour activity.

S0289 KIN1148 KIN1148 is an agonist of interferon regulatory factor 3 (IRF3) that induces dose-dependent IRF3 nuclear translocation and specific activation of IRF3-responsive promoters. KIN1148 is an influenza vaccine adjuvant that enhances flu vaccine efficacy.
S0433 Nucleozin Nucleozin is an antivirus agent that targets influenza A nucleoprotein (NP). Nucleozin triggers the aggregation of NP and inhibits its nuclear accumulation.
Nat Commun, 2022, 13(1):2079
S0861 Laninamivir Octanoate Laninamivir octanoate (CS-8958, R-118958, Inavir, LANI), a prodrug of Laninamivir (R-125489), is a long-acting neuraminidase (NA) inhibitor with superior anti-influenza virus activity.
S1627 Nitazoxanide (NSC 697855) Nitazoxanide (NTZ, NSC 697855) is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent(IC50 for canine influenza virus ranges from 0.17 to 0.21 μM). Nitazoxanide modulates autophagy and inhibits mTORC1 signaling.
Biochem Pharmacol, 2022, 197:114913
Oncol Lett, 2022, 23(4):123
Front Pharmacol, 2021, 12:781640
S1848 Curcumin Curcumin (Diferuloylmethane, Natural Yellow 3, Turmeric yellow) is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). It is an inhibitor of p300 histone acetylatransferase(IC50~25 μM)and Histone deacetylase (HDAC); activates Nrf2 pathway and supresses the activation of NF-κB. Curcumin induces mitophagy, autophagy, apoptosis, and cell cycle arrest with antitumor activity. Curcumin reduces renal damage associated with rhabdomyolysis by decreasing ferroptosis-mediated cell death. Curcumin exhibits anti-infective properties against various human pathogens like the influenza virus, hepatitis C virus, HIV and so on.
Phytother Res, 2022, 36(3):1326-1337
Dis Markers, 2022, 2022:3129781
Adv Sci (Weinh), 2021, e2103360
S1964 Rimantadine Rimantadine (Flumadine) is an anti-influenza virus drug for T. brucei with IC50 of 7 μM.
J Virol Methods, 2019, 274:113714
S2120 Arbidol HCl Arbidol HCl (Umifenovir) is a broad-spectrum antiviral compound that blocks viral fusion, used in treatment of influenza and other respiratory viral infections.
S2597 Oseltamivir Phosphate Oseltamivir Phosphate is a potent and selective inhibitor of the neuraminidase that is essential for replication of influenza A and B viruses, used to prevent influenza.
iScience, 2022, 25(4):104088
J Ethnopharmacol, 2021, S0378-8741(21)00290-7
J Cell Mol Med, 2018, 22(3):1826-1839
S2716 Peramivir Trihydrate Peramivir Trihydrate (BCX-1812, RWJ-270201, S-021812) is a trihydrate of the anti-infection agent peramivir which is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM.
Emerg Microbes Infec, 2014, 3, e78
Emerg Microbes Infect, 2014, 3(11):e78
S2869 Adamantane

Adamantane is a colorless, crystalline chemical compound first isolated from petroleum with a camphor-like odor. Adamantane is used to treat influenza A virus infections.

S3007 Zanamivir Zanamivir (GG167) is a neuraminidase inhibitor used in the treatment and prophylaxis of influenza caused by influenza A virus and influenza B virus.
Front Immunol, 2019, 10:2575
Emerg Microbes Infec, 2014, 3, e78
Emerg Microbes Infect, 2014, 3(11):e78
S4491 Cetylpyridinium chloride monohydrate Cetylpyridinium chloride (CPC, Hexadecylpyridinium chloride) monohydrate is a broad-spectrum antimicrobial agent that possesses virucidal activity against susceptible and resistant strains of influenza virus by targeting and disrupting the viral envelope.
S5499 Amantadine Amantadine (1-Adamantanamine, 1-Adamantylamine, 1-Aminoadamantane) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is an M2 inhibitor which blocks the ion channel formed by the M2 protein that spans the viral membrane.
S6854 Triazavirin Triazavirin (TZV, Riamilovir) is a novel antiviral drug, a nucleoside analogue of nucleic acid that inhibits the synthesis of viral RNA and DNA and replication of genomic fragments. Triazavirin is active against influenza and a number of other viruses. Triazavirin is an effective protective agent on the transmission stage of influenza.
S7273 SC75741 SC75741 is a potent NF-κB inhibitor with EC50 of 200 nM. SC75741 efficiently blocks influenza virus propagation.
Front Immunol, 2022, 13:839460
Int J Mol Sci, 2022, 23(6)3280
Microbiol Spectr, 2022, e0188121
S7975 Favipiravir (T-705) Favipiravir (T-705) is a potent and selective RNA-dependent RNA polymerase inhibitor, used to treat influenza virus infections.
Nat Commun, 2022, 13(1):2256
Antiviral Res, 2022, 199:105273
Rapid Commun Mass Spectrom, 2022, e9255
E0207New Chebulinic acid

Chebulinic acid, a phenolic compound isolated from Terminalia chebula fruit, is a novel Influenza viral neuraminidase inhibitor. Chebulinic acid is a antiangiogenic agent through inhibiting the actions of VEGF. Chebulinic acid shows antitumour activity.

Tags: Influenza Virus inhibitor|Influenza Virus agonist|Influenza Virus activator|Influenza Virus inducer|Influenza Virus antagonist|Influenza Virus signaling pathway|Influenza Virus assay kit