Home Microbiology Influenza Virus inhibitor Cetylpyridinium chloride monohydrate

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Cetylpyridinium chloride monohydrate Influenza Virus inhibitor

Cat.No.S4491

Cetylpyridinium chloride (CPC, Hexadecylpyridinium chloride) monohydrate is a broad-spectrum antimicrobial agent that possesses virucidal activity against susceptible and resistant strains of influenza virus by targeting and disrupting the viral envelope.
Cetylpyridinium chloride monohydrate Influenza Virus inhibitor Chemical Structure

Chemical Structure

Molecular Weight: 358

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Quality Control

Batch: S449101 DMSO]72 mg/mL]false]Water]72 mg/mL]false]Ethanol]72 mg/mL]false Purity: 99.98%
99.98

Solubility

In vitro
Batch:

DMSO : 72 mg/mL (201.11 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : 72 mg/mL

Ethanol : 72 mg/mL

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In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight 358 Formula

C21H40ClNO

 Storage (From the date of receipt) 3 years -20°C powder
CAS No. 6004-24-6 -- Storage of Stock Solutions

Synonyms CPC monohydrate, Hexadecylpyridinium chloride monohydrate Smiles O.[Cl-].CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1

Mechanism of Action

In vivo

Cetylpyridinium chloride (CPC) exposure significantly decreases the locomotor activity and social interaction of zebrafish at both life stages, and juveniles are more sensitive than adults. CPC exposure tends to increase the brain neurotransmitter levels of juveniles but decreases their levels in adults, in which the brain monoamine neurotransmitters and their turnover might play important roles in the life stage-dependent behavioral response to CPC.
References

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