| S2504 |
Ribavirin (ICN-1229)
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Ribavirin (NSC-163039, ICN-1229, RTCA, Tribavirin), a synthetic guanosine analogue, possesses a broad spectrum of activity against DNA and RNA viruses.
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Cancer Cell, 2025, 43(4):776-796.e14
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Cell Discov, 2025, 11(1):89
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Mol Ther, 2025, 33(3):1213-1225
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| S1807 |
Acyclovir (Aciclovir)
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Acyclovir (Aciclovir) is a synthetic nucleoside analogue active against herpesviruses, and it induces cell cycle perturbation and apoptosis in Jurkat leukemia cells.
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Int J Mol Sci, 2025, 26(15)7185
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Virol Sin, 2025, S1995-820X(25)00102-6
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Nat Commun, 2024, 15(1):9461
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| S2467 |
Famciclovir
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Famciclovir (BRL-42810) is a guanine analogue antiviral drug used for the treatment of various herpesvirus infections.
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iScience, 2024, 27(10):110862
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J Pers Med, 2022, 12(2)258
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Eur J Pharm Biopharm, 2022, S0939-6411(22)00047-9
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| S2486 |
Moroxydine HCl
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Moroxydine HCl(ABOB hydrochloride) is a synthetic antiviral compound chemically belonging to the series of the heterocyclic biguanidines.
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J Pers Med, 2022, 12(2)258
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Hum Cell, 2022, 10.1007/s13577-022-00671-y
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Biomedicines, 2021, 9(8)996
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| S2420 |
Aloperine
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Aloperine is an isolated alkaloid in sophora plants such as Sophora alopecuroides L, and exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.
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Cells, 2025, 14(12)929
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Cancer Cell Int, 2021, 21(1):662
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Tissue Cell, 2021, 74:101706
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| S4184 |
Penciclovir
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Penciclovir (BRL-39123, VSA 671,NSC-759624) is a purine acyclic nucleoside analogue with potent antiviral activity.
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Eur J Pharm Biopharm, 2022, S0939-6411(22)00047-9
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Antiviral Res, 2021, S0166-3542(21)00068-1
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ACS Infect Dis, 2021, 10.1021/acsinfecdis.1c00083
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| S2334 |
Oleanolic Acid
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Oleanolic Acid (Caryophyllin) is a non-toxic, hepatoprotective triterpenoid found in Phytolacca Americana, which exerts antitumor and antiviral properties.
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Sci Rep, 2024, 14(1):21852
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Front Pharmacol, 2021, 12:697483
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J Cell Sci, 2021, 134(8)jcs255273
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| S0936 |
Aloin B
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Aloin B (Isobarbaloin), isolated from Aloe vera, is one isomer of Aloin and has anti-hepatitis B virus (HBV) acyivity.
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Cytotechnology, 2025, 77(4):137
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Nan Fang Yi Ke Da Xue Xue Bao, 2023, 43(5):702-709
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| E2027 |
LL-37 acetate
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LL-37 acetate is a 37-residue, amphipathic, cathelicidin-derived peptide, which exhibits a broad spectrum of antimicrobial activity.
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Int J Mol Sci, 2025, 26(7)3156
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| S5684 |
Lapachol
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Lapachol (Tecomin, CI75490, Bethabarra wood, Greenhartin), a natural compound isolated from the bark of the lapacho tree, shows both antimicrobial and antiviral activity.
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Elife, 2020, 9e56773
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| S6289 |
Gentamicin
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Gentamicin, an aminoglycoside class of bactericidal antibiotic, is effective against gram-negative bacterial infections.This compound can be used to induce animal models of Renal Failure.
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Universitätsmedizin Berlin, 2021, 10.17169/refubium-29871
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| S1637 |
Docosanol
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Docosanol is a saturated fatty alcoholused traditionally as an emollient, emulsifier, and thickener in cosmetics, nutritional supplement. (ED50=2.5 mg/mL for plaque inhibition, and ED50=1.7 mg/mL for inhibition of virus production)
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| S1883 |
Idoxuridine
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Idoxuridine (NSC 39661, SKF 14287,5-Iodo-2′-deoxyuridine,5-IUdR,IdUrd) is an antiviral agent for feline herpesvirus type-1 with IC50 of 4.3 μM.
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| S9224 |
Dehydroandrographolide Succinate
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Dehydroandrographolide succinate (DAS), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, has antibacterial and antiviral effects.
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| S9278 |
Saikosaponin C
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Saikosaponin C is a triterpene saponin found in Bupleurum that exhibits antiviral and pro-angiogenic activities.
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| S4942 |
4-Hydroxy-3,5-dimethoxybenzyl alcohol
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4-Hydroxy-3,5-dimethoxybenzyl alcohol (Syringic alcohol, Syringyl alcohol) is a kind of phenol with antiviral properties.
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| E6043 |
Vidarabine phosphate
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Vidarabine phosphate (Vidarabine monophosphate, Ara-AMP) is a soluble nucleotide derivative of vidarabine, an antiviral agent. It demonstrates proven efficacy against herpes simplex virus, varicella zoster virus, and chronic hepatitis B infection.
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| E3359 |
Honeysuckle flower Extract
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Honeysuckle flower Extract is extracted from Lonicera japonica Thunb, which has antibacterial, antiviral, anti-inflammatory properties.
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| S3553 |
Riamilovir
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Riamilovir (Triazavirin) is a broad-spectrum antiviral drug candidate, which can be used for potential application against the Coronavirus 2019-nCoV.
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| S5016 |
Isoprinosine
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Isoprinosine (Inosine pranobex, Immunovir, Groprinosin, Delimmun) is an immunopharmacologic agent with antiviral activities.
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| E2110New |
Norwogonin
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Norwogonin, derived from Scutellaria baicalensis Georgi, exhibits antiviral effects against Enterovirus 71 (EV71), showing an IC50 value of 31.83 μg/ml.
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| S9078 |
Epigoitrin
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Epigoitrin (Goitrin, BA-51-090278), the main bioactive constituent of Radix isatidis, exerts antiviral, anticancer, and antithyroid activities.
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| E3409 |
Geranium wilfordii Extract
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Geranium wilfordii Extract is extracted from Geranium wilfordii, has anviral property.
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| S6067 |
2,4-dichlorobenzyl alcohol
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2,4-Dichlorobenzyl alcohol is a mild antiseptic, able to kill bacteria and viruses associated with mouth and throat infections.
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| S9328 |
5,6,7-Trimethoxyflavone
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5,6,7-Trimethoxyflavone (Baicalein Trimethyl Ether), methylations of the hydroxyl groups of oroxylin A or baicalein, has various pharmacological activities including antiviral, anticancer and antibacterial.
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| S9344 |
DL-Methionine
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DL-Methionine is an amino acid that has a role in the defence of oxidative stress.
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| S4518 |
Chloroxylenol
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Chloroxylenol is a broad-spectrum antimicrobial chemical compound used to control bacteria, algae, fungi and virus.
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| E3783 |
Spiraea Salicifolia Extract
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Spiraea Salicifolia Extract is obtained from Spiraea Salicifolia, which exerts potent antiviral activity against influenza A and B viruses.
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| E3788 |
Smallanthus Sonchifolius Extract
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Smallanthus Sonchifolius Extract is drawed from Smallantchus sonchifolius, which has antimicrobial, hypoglycemic, antiobesity, anticancer, and cholesterol-lowering activity.
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| E3800 |
Nidus Collocaliae Extract
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Nidus Collocaliae Extract is drawed from Nidus Collocaliae, which has anti-H5N1 virus effect probably through resisting hemagglutinin.
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| S4408 |
Procodazole
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Procodazole (Propazol, 2-Benzimidazolepropionic acid, 3-(1H-benzimidazole-2) propanoic acid) is used as a potentiator which is non-specific active immunoprotective against viral and bacterial infections.
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| S8071 |
UNC0638
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UNC0638 is a potent, selective and cell-penetrant chemical probe for G9a and GLP histone methyltransferase with IC50 of <15 nM and 19 nM, respectively, shows selectivity over a wide range of epigenetic and non-epigenetic targets. This compound has anti-viral activities.
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-
bioRxiv, 2025, 2025.07.01.662447
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Cell Rep, 2024, 43(2):113779
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Cell Rep, 2024, 43(8):114548
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| S9120 |
Scutellarein
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Scutellarein (6-Hydroxyapigenin), extracted from the perennial herb Scutellaria lateriflora, has antioxidant, antitumor, anti-adipogenic, antiviral and anti-inflammatory activities
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-
J Adv Res, 2025, S2090-1232(25)00499-0
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SLAS Discov, 2024, S2472-5552(24)00007-8
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| S9136 |
Neochlorogenic acid
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Neochlorogenic acid (Neochlorogenate, 5-O-Caffeoylquinic acid) is a natural polyphenolic compound found in some types of dried fruits and a variety of other plant sources such as peaches. It shows antioxidant, antibacterial, antiviral, and antipyretic activities and exerts neuroprotective effects through the inhibition of pro-inflammatory pathways in activated microglia.
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-
Biomacromolecules, 2024, 25(2):729-740
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| S5020 |
Tilorone dihydrochloride
|
Tilorone dihydrochloride is a broad-spectrum, orally active antiviral agent that activates interferon production. It has antitumor, anti-inflammatory properties.
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| S9099 |
Orientin
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Orientin (Lutexin, Luteolin-8-glucoside), isolated from medicinal plants, has various activities including anti-oxidant, anti-aging, anti-viral, anti-bacterial, anti-inflammation, vasodilatation and cardioprotective, antiadipogenesis, antinociceptive, radiation protective, neuroprotective, and antidepressant-like effects.
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| E3761 |
Elsholtzia Ciliata Extract
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Elsholtzia Ciliata Extract is obtained from Elsholtzia ciliata (Thunb.) Hyl.—an annual plant belonging to Lamiaceae Martinov family, which possesses anti-inflammatory, antiviral, antibacterial, antioxidant, anticancer, and vasorelaxant effects.
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