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Alkylating Agent

Alkylating Agent Products

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Cat.No. Product Name Information Product Use Citations Product Validations
S1237 TMZ(Temozolomide) TMZ(Temozolomide) is a monofunctional SN-1 alkylating agent that can modify nitrogen atoms in the DNA ring and the extracyclic oxygen group, chemically converted to MTIC and degrades to methyldiazonium cation, which transfers methyl groups to DNA at physiologic pH. A DNA damage inducer in L-1210 and L-1210/BCNU cells. Temozolomide induces apoptosis and exhibits antitumor activity.
Cancer Cell, 2025, S1535-6108(25)00223-5
Cancer Cell, 2025, 43(4):776-796.e14
Nat Commun, 2025, 16(1):4239
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S2057 Cyclophosphamide Monohydrate Cyclophosphamide Monohydrate is a nitrogen mustard alkylating agent, it attaches the alkyl group to the guanine base of DNA, shown to crosslink DNA, causing strand breakage and inducing mutations.Cyclophosphamide (NSC-26271) Monohydrate can be used to induce animal models of Anemia.
Cell Rep Med, 2025, S2666-3791(25)00102-8
Cell Mol Life Sci, 2025, 82(1):164
Int J Mol Sci, 2025, 26(17)8494
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S1217 Cyclophosphamide Cyclophosphamide(NSC 26271,Endoxan, Cytoxan, Neosar, Procytox, Revimmune, Cytophosphane) is a nitrogen mustard alkylating agent from the oxazophorines group.
Neurotherapeutics, 2025, 22(1):e00480
Sci Rep, 2025, 15(1):2893
Cancers (Basel), 2024, 16(21)3565
Verified customer review of Cyclophosphamide