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Isoform-selective Products

Cat.No. Product Name Information Product Use Citations Product Validations
S1633 Zafirlukast Zafirlukast is an oral leukotriene receptor antagonist (LTRA), used to prevent asthma symptoms.
Communications Medicine, 2025, 420
Int J Immunopathol Pharmacol, 2025, 39:3946320251351083
Antimicrobial Agents and Chemotherapy, 2024, e00168-24
S4211 Montelukast Sodium Montelukast Sodium selectively antagonizes leukotriene D4 (LTD4) by binding to it so that block the action of leukotriene D4 on the cysteinyl leukotriene receptor CysLT1. Montelukast improves macroautophagy but not the chaperone-mediated autophagy pathway. Solutions are unstable and should be fresh-prepared.
Sci Rep, 2025, 15(1):12720
Scientific Reports, 2025, 12720
Biochem Biophys Res Commun, 2022, 594:31-37
S5783 Montelukast Montelukast(MK0476) is a leukotriene receptor antagonist used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies.
Eur J Pharmacol, 2024, 985:177058
Biochem Biophys Res Commun, 2022, 594:31-37
Cancer Immunol Immunother, 2021, 70(1):203-213
S0505 MK-571 sodium salt MK-571 sodium salt (L-660711) is a selective, orally active antagonist of leukotriene D4 receptor. It is also an inhibitor of multidrug resistance-associated protein MRP4 (ABCC4) and ABCC1 (MRP1).
Diagnostics -Basel), 2023, 13(16)2646
Diagnostics (Basel), 2023, 13(16)2646
Cancers (Basel), 2022, 14(11)2643
S2959 LY255283 LY255283 is an antagonist of leukotriene B4 (LTB4) receptor (BLT2) that displaces [3H]LTB4 from its binding site on lung membranes with pKi of 7.0.
Journal of Translational Medicine, 2023, 923
J Transl Med, 2023, 21(1):923
S0428 Etalocib Etalocib(LY293111, VML295) is a leukotriene B4 receptor (LTB4R) antagonist that blocks activation of human neutrophils.
S8126 MK-571 (L-660711) MK571 is a selective, orally active CysLT1 receptor(Cysteinyl leukotriene receptor) antagonist.
Nat Commun, 2025, 16(1):6942
Nature Communications, 2025, 6942
STAR Protoc, 2025, 6(2):103777
Verified customer review of MK-571 (L-660711)
S3998 (+)-α-Lipoic acid (+)-α-Lipoic acid ((R)-(+)-α-Lipoic acid, α-Lipoic acid, Alpha-Lipoic acid), a physiological form of thioctic acid, is a strong antioxidant that relieves diabetic neuropathic symptoms. It shows superior antioxidative effects to its racemate. This compound is an essential cofactor of mitochondrial enzyme complexes. This chemical inhibits NF-κB-dependent HIV-1 LTR activation.
J Clin Invest, 2024, 134(22)e181314
The Journal of Clinical Investigation, 2024, e181314
E2671 SR 2640 hydrochloride SR2640 hydrochloride is a potent and selective competitive leukotriene D4/E4 antagonist.