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Sulbactam Anti-infection inhibitor

Name: Sulbactam
Brand: Selleck Chemicals
SKU: S1958
Availability: InStock
Rating: 5 (1 reviews)

Cat.No.S1958

Sulbactam(CP45899) is a beta-lactamase inhibitor with an average IC50 of 0.8 μM.

Chemical Structure

Molecular Weight: 233.24

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Quality Control

Batch: Purity: 99.76%

99.76

Related Targets	Integrase Bacterial Antibiotics Fungal Antiviral COVID-19 Parasite Reverse Transcriptase HIV HCV Protease
Other Anti-infection Inhibitors	Clorsulon Sodium Tauroursodeoxycholate (TUDC) Cinchonidine Berberine chloride hydrate Chlorquinaldol p-Coumaric Acid Ascomycin (FK520) LL37 (Human cathelicidin) Cetrimonium Bromide (CTAB) Nitidine Chloride

Solubility

In vitro
Batch:

DMSO : 47 mg/mL (201.5 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : 47 mg/mL

Ethanol : 47 mg/mL

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
Mass value Mass unit	Concentration value Concentration unit	Volume value Volume unit	Molecular weight (g/mol)

Dilution Calculator Molecular Weight Calculator

In vivo batch selection In vivo Batch:
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal: μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO

% Tween 80

% ddH₂O

% DMSO

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight	233.24	Formula	C₈H₁₁NO₅S	Storage (From the date of receipt)	3 years-20°Cpowder
CAS No.	68373-14-8	Download SDF		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent
Synonyms	CP45899			Smiles	CC1(C(N2C(S1(=O)=O)CC2=O)C(=O)O)C

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT02688322	Completed	Acinetobacter Infections	Sutep Jaruratanasirikul\|Prince of Songkla University	September 2014	Phase 4
NCT01118403	Withdrawn	Ventilator Associated Pneumonia	Hospital Pablo Tobón Uribe	March 2011	Phase 4
NCT00137007	Completed	Pneumonia	Pfizer	November 2003	Phase 4

Tech Support

Handling Instructions

Tel: +1-832-582-8158 Ext:3

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