Pramipexole

Catalog No.S2460 Synonyms: SND 919

Pramipexole Chemical Structure

Molecular Weight(MW): 211.33

Pramipexole is a partial/full D2S, D2L, D3, D4 receptor agonist with a Ki of 3.9, 2.2, 0.5 and 5.1 nM for D2S, D2L, D3, D4 receptor, respectively.

Size Price Stock Quantity  
In DMSO USD 90 In stock
USD 70 In stock
USD 170 In stock
USD 370 In stock
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Biological Activity

Description Pramipexole is a partial/full D2S, D2L, D3, D4 receptor agonist with a Ki of 3.9, 2.2, 0.5 and 5.1 nM for D2S, D2L, D3, D4 receptor, respectively.
Targets
D3 receptor [1] D2L Receptor [1] D2S Receptor [1] D4 receptor [1]
0.5 nM(Ki) 2.2 nM(Ki) 3.9 nM(Ki) 5.1 nM(Ki)
Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
CHO cells Mn7pSpVv[3Srb36gZZN{[Xl? NW\WSFBuUGmpaDDpcohq[mm2aX;uJINwdnO2YX70JIFo[Wmwc4SgX|NJZXOyaYDldo9v\SCkaX7kbY5oKHSxIHj1cYFvKESxcHHtbY5mKHKnY3XweI9zKER|IHX4dJJme3OnZDDpckBEUE9iY3XscJMtKEurPUCuPFghdk1? Mm\SNVU5ODF6M{m=

... Click to View More Cell Line Experimental Data

Protocol

Solubility (25°C)

In vitro DMSO 42 mg/mL (198.74 mM)
Ethanol 42 mg/mL (198.74 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 211.33
Formula

C10H17N3S

CAS No. 104632-26-0
Storage powder
Synonyms SND 919

Bio Calculators

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Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

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Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

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This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

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Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT01441284 Not yet recruiting Essential Tremor University of Pecs March 2017 Phase 3
NCT02660060 Completed Healthy Dexa Medica Group May 2015 --
NCT02347059 Unknown status Parkinsons Disease University of Toronto|Michael J. Fox Foundation for Parkinsons Research January 2015 Phase 2
NCT02397837 Recruiting Bipolar Disorder Icahn School of Medicine at Mount Sinai|The Zucker Hillside Hospital|Northwell Health|National Institute of Mental Health (NIMH) October 2014 Phase 4
NCT02217332 Active, not recruiting Chronic Sinusitis With Nasal Polyps and Eosinophilia Knopp Biosciences August 2014 Phase 2
NCT02033369 Recruiting Major Depressive Disorder New York State Psychiatric Institute|Columbia University|Research Foundation for Mental Hygiene, Inc.|Mclean Hospital|Icahn School of Medicine at Mount Sinai|National Institute of Mental Health (NIMH) February 2014 Phase 4

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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Dopamine Receptor Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID