Histone deacetylases

Cat.No.	Product Name	Added

S2244	AR-42 (HDAC-42)	Jun 2011
AR-42 is a novel HDAC inhibitor with an IC50 of 0.61 μM for acute lymphoblastic leukemia (697) cell lines.

S1085	Belinostat (PXD101)	Jul 2009
Belinostat also known as PXD101 is a HDAC inhibitor with IC50 of 27 nM.

S1194	CUDC-101	May 2010
CUDC-101 is a potent multitargeted HDAC, EGFR and HER2 inhibitor with IC50 of 4.4, 2.4, and 15.7 nM, respectively.

S1422	Droxinostat	Jul 2010
Droxinostat is a selective inhibitor of HDAC3, HDAC6, and HDAC8 (IC50 at 16.9 ,2.47 and 1.46 μM, respectively).

S2170	ITF2357 (Givinostat)	Jan 2011
ITF2357 (Givinostat) is a noverl HDAC inhibitor with IC50 of 10, 7.5 and 16 nM for maize HDAC preparations HD2, HD-1B and HD-1A, respectively.

S1096	JNJ-26481585	Aug 2009
JNJ-26481585 is an orally bioavailable, second-generation, hydroxamic acid-based HDAC inhibitor with an IC50 of 2.43 nM for 5T33MMvt cells.

S1095	LAQ824 (NVP-LAQ824)	Aug 2009
LAQ824 (NVP-LAQ824) is an HDAC inhibitor with an IC50 of 0.032 μM.

S1030	LBH589 (Panobinostat)	Apr 2009
LBH589 (Panobinostat) is a HDAC inhibitor, IC50 for inhibition of proliferation in MOLT-4 cells is approximately 5 μM and for Reh cells is approximately 20 μM.

S1484	MC1568	Sep 2010
MC1568 is a potent selective class II (IIa) histone deacetylas (HDAC II) inhibitor (IC50 of a maize deacetylase HD2 at 22.0 µM).

S1122	MGCD0103 (Mocetinostat)	Oct 2009
MGCD0103 (Mocetinostat) is a potent HDAC inhibitor with IC50 of 0.15, 0.29 and 1.66 μM for HDAC 1, HDAC 2 and HDAC 3, respectively.

S1053	MS-275 (Entinostat)	Apr 2009
MS-275 (Entinostat) is a potent HDAC inhibitor with IC50 of 0.3 and 8µM for HDAC1 and HDAC3, respectively.

S1090	PCI-24781	Jul 2009
PCI-24781 (CRA-024781) is an HDAC inhibitor with Ki of 7 μM.

S1515	SB939	Sep 2010
SB939 is a novel potent and orally active histone deacetylase inhibitor with an IC50 of 52 nM for HDAC1 and a GI50 of 0.56 µM for Colo205.

S1045	Trichostatin A (TSA)	Apr 2009
Inhibitor of HDAC, HDAC inhibitory activity of TSA was similar in all cell lines with mean ± SD IC50 of 2.4 ± 0.5 nm (range, 1.5–2.9 nm)

S2627	Tubastatin A hydrochloride	Aug 2011
Tubastatin A hydrochloride is a potent selective HDAC6 inhibitor with an IC50 of 15 nM.

S1168	Valproate	Mar 2010
Valproate is a histone deacetylase inhibitor with an IC50 of 0.4 mM and exhibits anticancer, anti-inflammatory and neuroprotective effects.

S1047	Vorinostat (SAHA)	Apr 2009
Vorinostat also known as SAHA, Zolinza, MK-0683 is an HDAC inhibitor. Vorinostat CAS No 149647-78-9 with purity >99% & solubility DMSO is available.