HD1 Selective Inhibitors

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S1484 MC1568

MC1568 is a selective HDAC inhibitor for maize HD1-A with IC50 of 100 nM. It is 34-fold more selective for HD1-A than HD1-B.

Selective HD1-B (Maize), IC50: 3.4 μM; HD1-A (Maize), IC50: 100 nM
S2170 Givinostat (ITF2357)

Givinostat (ITF2357) is a potent HDAC inhibitor for maize HD2, HD1B and HD1A with IC50 of 10 nM, 7.5 nM and 16 nM. Phase 2.

Pan HD1-B, IC50: 7.5 nM; HD1-A, IC50: 16 nM