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S1060
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Olaparib (AZD2281) |
Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1 and PARP2 with IC50 of 5 nM and 1 nM, respectively. |
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S1004
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ABT-888 (Veliparib) |
ABT-888 (Veliparib, NSC 737664) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM, respectively. |
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S1098
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Rucaparib (AG-014699 , PF-01367338) |
Rucaparib (AG-014699, PF-01367338) is an inhibitor of PARP with Ki of 1.4 nM. |
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S1087
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Iniparib (BSI-201) |
BSI-201 (Iniparib, SAR240550) is a PARP1 inhibitor. |
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S2197
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A-966492 |
A-966492 is a novel and potent inhibitor of PARP1 and PARP2 with Ki of 1 nM and 1.5 nM, respectively. |
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S7048
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BMN 673 |
BMN 673 is a novel PARP inhibitor with IC50 of 0.58 nM. |
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S8038
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UPF 1069 |
UPF 1069 is a selective PARP2 inhibitor with IC50 of 0.3 μM. |
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S2178
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AG14361 |
AG14361 is a potent inhibitor of PARP1 with Ki of < 5 nM. |
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S1132
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INO-1001 |
INO-1001 is a potent inhibitor of PARP with IC50 of 50 nM and a mediator of oxidant-induced myocyte dysfunction during reperfusion. |
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S2741
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MK-4827 |
MK-4827 is an selective inhibitor of PARP1 and PARP2 with IC50 of 3.8 nM and 2.1 nM, respectively. |
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