DNA alkylator

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S1312 Streptozotocin (STZ) 53 mg/mL 53 mg/mL <1 mg/mL
S1692 Busulfan <1 mg/mL 49 mg/mL <1 mg/mL
S2057 Cyclophosphamide Monohydrate 7 mg/mL 55 mg/mL <1 mg/mL
S1278 Altretamine <1 mg/mL 15 mg/mL 33 mg/mL
S7829 CB1954 <1 mg/mL 50 mg/mL <1 mg/mL
S8266 Melphalan <1 mg/mL 10 mg/mL <1 mg/mL
Catalog No. Information Product Use Citations Product Validations
S1312

Streptozotocin (STZ)

Streptozotocin is a glucosamine-nitrosourea derivative, which is a methylating, carcinogenic, antibiotic and diabetes inducing agent.

S1692

Busulfan

Busulfan is a cell cycle non-specific alkylating antineoplastic agent.

S2057

Cyclophosphamide Monohydrate

Cyclophosphamide Monohydrate is a nitrogen mustard alkylating agent, it attaches the alkyl group to the guanine base of DNA, shown to crosslink DNA, causing strand breakage and inducing mutations.

S1278

Altretamine

Altretamine is an anti-neoplastic agent.

S7829New

CB1954

CB1954(Tretazicar) is a anticancer prodrug that is converted in the presence of the enzyme NQO2 and co-substrate caricotamide ( EP-0152R) (EP) into a potent cytotoxic bifunctional alkylating agent. It can be activated by NAD(P)H quinone oxidoreductase 2.

S8266New

Melphalan

Melphalan is a phenylalanine derivative of nitrogen mustard with antineoplastic activity.

Catalog No. Information Product Use Citations Product Validations
S1312

Streptozotocin (STZ)

Streptozotocin is a glucosamine-nitrosourea derivative, which is a methylating, carcinogenic, antibiotic and diabetes inducing agent.

S1692

Busulfan

Busulfan is a cell cycle non-specific alkylating antineoplastic agent.

S2057

Cyclophosphamide Monohydrate

Cyclophosphamide Monohydrate is a nitrogen mustard alkylating agent, it attaches the alkyl group to the guanine base of DNA, shown to crosslink DNA, causing strand breakage and inducing mutations.

2013, 73(20):6310-22

S1278

Altretamine

Altretamine is an anti-neoplastic agent.

S7829New

CB1954

CB1954(Tretazicar) is a anticancer prodrug that is converted in the presence of the enzyme NQO2 and co-substrate caricotamide ( EP-0152R) (EP) into a potent cytotoxic bifunctional alkylating agent. It can be activated by NAD(P)H quinone oxidoreductase 2.

S8266New

Melphalan

Melphalan is a phenylalanine derivative of nitrogen mustard with antineoplastic activity.