ROS Chemicals

Cat.No.	Product Name	Information	Product Use Citations
S7551	Piperlongumine	Piperlongumine (PPLGM, Piplartine), a natural alkaloid from Piper longum L., increases the level of reactive oxygen species (ROS) and selectively kills cancer cells. It is a direct TrxR1 inhibitor with suppressive activity against gastric cancer and a novel inhibitor of CRM1; also an inhibitor of PI3K/Akt/mTOR in human breast cancer cells.	Biochim Biophys Acta Mol Basis Dis, 2025, 1871(3):167687 Eur J Pharmacol, 2025, 997:177478 PLoS One, 2025, 20(9):e0333127
S9687	H2DCFDA (DCFH-DA)	H2DCFDA (DCFH-DA) is a cell-permeable probe used to detect intracellular reactive oxygen species (ROS) production. It is de-esterified intracellularly and turns to highly fluorescent 2′,7′-dichlorofluorescein upon oxidation. This compound is used in sensitive and rapid quantitation of oxygen-reactive species in response to oxidative metabolism; microplate assay for detecting oxidative products in phagocytic cells, and quantitative multiwell myeloid differentiation assay.(Ex/Em=488/525 nm)	Nat Commun, 2024, 15(1):1750 J Exp Clin Cancer Res, 2023, 42(1):236 Free Radic Biol Med, 2023, 204:301-312
S2332	Neohesperidin	Neohesperidin (NSC 31048), a flavanone glycoside found in citrus fruits, is an antioxidant agent.	J Nutr Biochem, 2024, 136:109804 Transl Oncol, 2023, 35:101712 Curr Opin Colloid Interface Sci, 2021, 101461
S2605	Idebenone	Idebenone (CV-2619) is a synthetic analog of coenzyme Q10 (CoQ10) and a brain stimulant. This compound is known for its neuroprotective properties and is often used in research related to mitochondrial diseases. It has also been studied for its potential benefits in treating cognitive decline.	Molecules, 2025, 30(18)3772 Nature, 2024, 626(7998):411-418. Science, 2022, 375(6586):1254-1261
S2062	Tiopronin	Tiopronin is an antioxidant agent, used for the treatment of cystinuria by controlling the rate of cystine precipitation and excretion.	Nature, 2024, 629(8011):450-457 J Immunother Cancer, 2024, 12(11)e009805
S9021	(20R)Ginsenoside Rg3	(20R)Ginsenoside Rg3 is extracted from traditional Chinese medicine, red ginseng. It has a role as an antioxidant and a plant metabolite.	J Agric Food Chem, 2021, 69(21):6073-6086 Bioorg Chem, 2021, 111:104844 Environ Toxicol, 2020, 10.1002/tox.22899
S3885	Pyrogallol	Pyrogallol (1,2,3-trihydroxybenzene), an organic compound belonging to the phenol family, used as a photographic film developer and in the preparation of other chemicals. It is known to be a superoxide anion generator and ROS inducer.	Life Sci, 2023, 329:121972 Parasit Vectors, 2020, 13(1):449 Parasites & Vectors, 2020, 449-2020)
S4580	Hydroquinone	Hydroquinone (Quinol, 1,4-Benzenediol, 1,4-Dihydroxybenzene, HQ) is a Melanin Synthesis Inhibitor. The physiologic effect of hydroquinone is by means of Depigmenting Activity. It also posesses antioxidant properties that can cause toxicity in several organs, notably the kidney.This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.	Theranostics, 2022, 12(5):2063-2079 Neurotox Res, 2020, 2
S5709	Norgestrel	Norgestrel (WY-3707, SH-70850, SH-850, FH 122-A) is synthetic steroidal progestin that is used in combination with ethinyl estradiol for oral contraception. It also has strong neuroprotective activity.	Cancer Cell, 2025, 43(4):776-796.e14
S3222	Raspberry ketone glucoside	Raspberry ketone glucoside (RKG), a natural product in raspberry fruit, is an antioxidant that has the inhibitory effect on the melanin synthesis.
E0224	Chicoric acid	Chicoric acid is an orally active dicaffeoyltartaric acid with antioxidant, anti-inflammatory, and antidiabetic properties. It induces ROS generation and triggers mitochondria-dependent apoptosis in 3T3-L1 preadipocytes via PI3K/Akt and MAPK pathways. It also enhances glucose uptake and improves insulin resistance.
S4970	Nerol	Nerol (Cis-Geraniol, Neryl alcohol) is a monoterpene found in many essential oils such as lemongrass and hops. This compound has antifungal activity, and it can trigger mitochondrial dysfunction and disruption via elevation of Ca2+ and ROS leading to apoptosis.
S5314	HTHQ (1-O-Hexyl-2,3,5-trimethylhydroquinone)	HTHQ (1-O-Hexyl-2,3,5-trimethylhydroquinone), a hydroquinone monoalkylether, is a potent anti-oxidative and anti-lipid-peroxidative agent. This compound has considerable anti-oxidative activity by directly reacting with reactive oxygen species (ROS), including peroxyl radicals, and scavenging them to form more stable free radicals.
S3838	Carnosic acid	Carnosic acid (Salvin) is a phenolic diterpene, endowed with antioxidative and antimicrobial properties. It is increasingly used within food, nutritional health and cosmetics industries.	ACS Sustain Chem Eng, 2023, 11(12):4727-4737 Am J Cancer Res, 2020, 1;10(5):1442-1454 J Reprod Dev, 2020, 10.1262/jrd.2020-086
S3840	Baohuoside I	Baohuoside I (Icariside II) is a flavonoid isolated from Epimedium koreanum Nakai with anti-inflammatory and anti-cancer activities. It may exert cytotoxic effect via the ROS/MAPK pathway.
S9034	Isochlorogenic acid C	Isochlorogenic acid C (3,4-Dicaffeoylquinic acid; 4,5-Dicaffeoylquinic acid), which is a di-O-caffeoyl derivative of chlorogenic acid, is a well-known antioxidant from herbal plants and shows anti-viral effects against EV71.
E3399	Kelp Extract	Kelp Extract is extrcated from Laminariales, which can reduce the generation of endogenous reactive oxygen species.
S4511	6-Benzylaminopurine	6-Benzylaminopurine is a first-generation synthetic cytokinin which could regulate the activities of the antioxidant defense system of plants.Its treatment elicits plant growth and development.
E3495	Oyster Peptide	Oyster peptide enhances the function of the pituitary gonad axis and lowers ROS generation.