Neohesperidin

Catalog No.S2332 Synonyms: NSC 31048

Neohesperidin Chemical Structure

Molecular Weight(MW): 610.56

Neohesperidin, a flavanone glycoside found in citrus fruits, is an antioxidant agent.

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Biological Activity

Description Neohesperidin, a flavanone glycoside found in citrus fruits, is an antioxidant agent.
In vitro

Neohesperidin, a flavanone glycoside found in citrus fruits, is an antioxidant agent. Neohesperidin is an antioxidant agent with an IC50 of 22.31 μg/ml in the 1,1-diphenyl-2-picryldydrazyl (DPPH) radical-scavenging assay. Neohesperidin (50 mg/kg) significantly inhibits HCl/ethanol-induced gastric lesions, and increases the mucus content. In pylorus ligated rats, neohesperidin (50 mg/kg) significantly decreases the volume of gastric secretion and gastric acid output, and increases the pH. [1] In addition, Neohesperidin inhibits the growth of Caco-2, CEM/ADR5000 and CCRF-CEM leukaemia cells with IC50 of 0.17, 0.17 and 0.12 mM, respectively. [2]

Protocol

Solubility (25°C)

In vitro DMSO 122 mg/mL (199.81 mM)
Water Insoluble
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 610.56
Formula

C28H34O15

CAS No. 13241-33-3
Storage powder
Synonyms NSC 31048

Bio Calculators

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID