Catalog No.S2332 Synonyms: NSC 31048
Molecular Weight(MW): 610.56
Neohesperidin, a flavanone glycoside found in citrus fruits, is an antioxidant agent.
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|Description||Neohesperidin, a flavanone glycoside found in citrus fruits, is an antioxidant agent.|
Neohesperidin, a flavanone glycoside found in citrus fruits, is an antioxidant agent. Neohesperidin is an antioxidant agent with an IC50 of 22.31 μg/ml in the 1,1-diphenyl-2-picryldydrazyl (DPPH) radical-scavenging assay. Neohesperidin (50 mg/kg) significantly inhibits HCl/ethanol-induced gastric lesions, and increases the mucus content. In pylorus ligated rats, neohesperidin (50 mg/kg) significantly decreases the volume of gastric secretion and gastric acid output, and increases the pH.  In addition, Neohesperidin inhibits the growth of Caco-2, CEM/ADR5000 and CCRF-CEM leukaemia cells with IC50 of 0.17, 0.17 and 0.12 mM, respectively. 
|In vitro||DMSO||122 mg/mL (199.81 mM)|
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