TpoR

Other Immunology & Inflammation Related Inhibitors

CXCR AhR STING COX IL Receptor gp120/CD4 NOD NADPH-oxidase ROS Nrf2

Cat.No.	Product Name	Information	Product Use Citations
S2229	Eltrombopag Olamine	Eltrombopag Olamine is a member of the biarylhydrazone class, which is a nonpeptide agonist of the thrombopoietin receptor (TpoR).	J Transl Med, 2025, 23(1):69 iScience, 2024, 27(10):110862 J Mol Cell Biol, 2023, 15(3)mjad017
S4502	Eltrombopag (SB-497115)	Eltrombopag (SB-497115), a member of the biarylhydrazone class, is a nonpeptide agonist of the thrombopoietin receptor (TpoR), used to treat chronic hepatitis C-associated thrombocytopenia and chronic immune (idiopathic) thrombocytopenia (ITP).	BMC Biol, 2025, 23(1):24 Hemasphere, 2023, 7(6):e906 Am J Cancer Res, 2022, 12(6):2697-2710
S6624	Avatrombopag	Avatrombopag (AKR-501,E5501,YM477) is an orally administered, small-molecule thrombopoietin receptor (c-Mpl) agonist which increases platelet number, but not platelet activation.	Cell Death Dis, 2024, 15(12):932
E1352	Butyzamide	Butyzamide is a non-peptidyl thrombopoietin receptor, activator of Mpl . It also augments the phosphorylation level of JAK2, STAT3, STAT5 and MAPK. It has potential for treatment of thrombocytopenia.
E4969	Avatrombopag hydrochloride	Avatrombopag hydrochloride(AKR-501 hydrochloride, YM477 hydrochloride) is an orally administered second generation agonist of Thrombopoietin receptor(TpoR) with an EC50 value of 3.3 nM. It is used in the treatment of primary chronic immune thrombocytopenia (ITP).
S6988	Lusutrombopag	Lusutrombopag is an orally bioavailable thrombopoietin (TPO) receptor agonist being developed for chronic liver disease (CLD).