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Reductase

Other Metabolism Related Inhibitors

Dehydrogenase Transferase DPP Aminopeptidase Procollagen C Proteinase P450 (e.g. CYP17) Phospholipase (e.g. PLA) Factor Xa PDE DHFR
Cat.No. Product Name Information Product Use Citations Product Validations
S9103 Ginsenoside Ro Ginsenoside Ro (Chikusetsusaponin V), one of the high-abundance saponins in ginseng, is widely used as a dietary supplement and has many health-promoting effects.
S1202 Dutasteride Dutasteride (GI198745, GG-745) is a dual 5-α reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone (DHT).
Chemical and Pharmaceutical Bulletin, 2025, 857-867
Neoplasia, 2024, 101045
Neoplasia, 2024, 57:101045
S2404 Isoliquiritigenin Isoliquiritigenin, an anti-tumor flavonoid from the root of Glycyrrhiza glabra, inhibits aldose reductase with an IC50 of 320 nM.
Proceedings of the National Academy of Sciences, October 16 2018, E9869-E9878
The American Journal of Chinese Medicine, November 04 2023, 2221-2241
J Nutr Biochem, 2024, 136:109808
Verified customer review of Isoliquiritigenin
S1197 Finasteride Finasteride (MK-906) is a potent, reversible inhibitor of the rat type 1 5 alpha-reductase with Ki of 10.2 nM, used in the treatment of benign prostatic hyperplasia (BPH) and male pattern baldness (MPB).
PLoS One, June 2, 2016, e0156549
Frontiers in Pharmacology, February 20, 2023, 1038039
Biochem Pharmacol, 2025, 241:117171
S2035 Epalrestat Epalrestat is an aldose reductase inhibitor with IC50 of 72 nM.
Cell Rep Med, 2023, 4(6):101056
Free Radic Biol Med, 2021, 163:220-233
J Agric Food Chem, 2020, 68(42):11747-11757
S9170 Engeletin Engeletin (Dihydrokaempferol 3-rhamnoside), a bioactive flavonoid, has multiple biological activities such as anti-diabetic and anti-inflammatory effects. engeletin againsts LPS-stimulated endometritis in mice via negative regulation of pro-inflammatory mediators via the TLR4-regulated NF-κB pathway.
Journal of Inflammation Research, October 10, 2022, 5767-5783
Journal of Inflammation Research, 2022, 5767-5783
J Inflamm Res, 2022, 15:5767-5783
S5803 Alrestatin Alrestatin is an inhibitor of aldose reductase which is involved in the pathogenesis of complications of diabetes mellitus, including diabetic neuropathy.
iScience, 2022, 25(4):104153
S5910 Alpha-Estradiol Alpha-Estradiol (α-Estradiol, 17 alpha-Estradiol, Alfatradiol, Epiestradiol, Epiestrol, Alora, 17 α-E2), a natural, non-feminizing stereoisomer, a hormonally almost inactive isomer of physiological 17 beta-estradiol (17 β-E2), is a weak inhibitor of estrogen.
Biomater Res, 2024, 28:0010
S3818 Tectoridin Tectoridin (Shekanin), an isoflavone isolated from flowers of Pueraria thunbergiana, has several pharmacological effects including anti-cancer, anti-inflammatory, antioxidant, and hepatoprotectivy.
S1074 Poliumoside Poliumoside exhibits significant inhibition of advanced glycation end product formation with IC50 values of 19.69 µM. In the rat lens aldose reductase assay. This compound exhibits greater inhibitory effects on rat lens aldose reductase(RLAR) with IC50 values of 8.47 µM.