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Suberohydroxamic acid

Name: Suberohydroxamic acid
Brand: Selleck Chemicals
SKU: S5905

Catalog No.S5905 Synonyms: suberic bishydroxamic acid

For research use only.

Suberohydroxamic acid (suberic bishydroxamic acid) is a competitive HDAC inhibitor with IC50 values of 0.25 and 0.3 μM for HDAC1 and HDAC3 respectively.

Suberohydroxamic acid Chemical Structure

CAS No. 38937-66-5

Purity & Quality Control

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HDAC Signaling Pathway Map

Biological Activity

Description

Suberohydroxamic acid (suberic bishydroxamic acid) is a competitive HDAC inhibitor with IC50 values of 0.25 and 0.3 μM for HDAC1 and HDAC3 respectively.

Targets

HDAC1 ^[1] (Cell-free assay)	HDAC3 ^[1] (Cell-free assay)
0.25 μM	0.3 μM

Protocol (from reference)

References

[1] Richon VM, et al. Proc Natl Acad Sci U S A. 1998, 95(6):3003-7.

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight	204.22
Formula	C₈H₁₆N₂O₄
CAS No.	38937-66-5
Storage	3 years	-20°C	powder
Storage	2 years	-80°C	in solvent
Smiles	C(CCCC(=O)NO)CCC(=O)NO

In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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