Name: Moxidectin
Brand: Selleck Chemicals
SKU: S3713
Availability: InStock
Rating: 5 (1 reviews)

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Quality Control

Batch: Purity: 99.23%

99.23

Related Targets	Integrase Bacterial Antibiotics Anti-infection Fungal Antiviral COVID-19 Reverse Transcriptase HIV HCV Protease
Other Parasite Inhibitors	Diminazene Aceturate Oxfendazole Oxibendazole (+/-)-nerolidol Emodepside Avermectin B1 Milbemycin Oxime Arteether Eprinomectin Diclazuril

Solubility

In vitro
Batch:

DMSO : 100 mg/mL (156.29 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Ethanol : 100 mg/mL

Water : Insoluble

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
Mass value Mass unit	Concentration value Concentration unit	Volume value Volume unit	Molecular weight (g/mol)

Dilution Calculator Molecular Weight Calculator

In vivo batch selection In vivo Batch:
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
	5%DMSO 1 40%PEG300 2 5%Tween80 3 50%ddH2O Validated by Selleck labs. Should you need adjustments to this formulation, contact our sales team for custom testing.	5.000mg/ml (7.81mM)
	5% DMSO 1 95% Corn oil Validated by Selleck labs. Should you need adjustments to this formulation, contact our sales team for custom testing.	5.000mg/ml (7.81mM)
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal: μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO

%

% Tween 80

% ddH₂O

% DMSO

+

%

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight	639.82	Formula	C₃₇H₅₃NO₈	Storage (From the date of receipt)	3 years-20°Cpowder
CAS No.	113507-06-5	Download SDF		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent
Synonyms	Milbemycin B			SMILES	CC1CC(=CCC2CC(CC3(O2)CC(=NOC)C(C(O3)C(=CC(C)C)C)C)OC(=O)C4C=C(C(C5C4(C(=CC=C1)CO5)O)O)C)C

Read more about storage stability stock solution CAS number SMILES

Mechanism of Action

In vivo	In human, MOX is generally safe and well tolerated, with a slightly higher incidence of transient, mild, and moderate central nervous system AEs as the dose increased. The PKs of MOX are dose proportional within the dose range studied, and the elimination half-life (t1/2 elim) is long (mean: 20.2-35.1 days).
References	[1] https://pubmed.ncbi.nlm.nih.gov/23133688/ [2] https://pubmed.ncbi.nlm.nih.gov/14517193/

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2025-11-21)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT07145736	RECRUITING	Onchocerciasis; Ascaris Lumbricoides Infection; Trichuris Trichiura; Infection; Hookworm Infections; Scabies	Kirby Institute	2025-08-04	PHASE4
NCT07159373	NOT_YET_RECRUITING	Lymphatic Filariasis; Scabies; Strongyloidiasis	Medicines Development for Global Health	2026-03	PHASE3
NCT06070116	ACTIVE_NOT_RECRUITING	Onchocercal Subcutaneous Nodule; Onchocerciasis; Onchocerciasis, Ocular; Onchocerca Infection; Tropical Disease	Washington University School of Medicine	2024-04-05	PHASE2
NCT06795165	COMPLETED	Blepharitis	Eye Research Foundation, Inc.	2025-02-02	PHASE4
NCT05875441	COMPLETED	Scabies	Medicines Development for Global Health	2023-11-23	PHASE2
NCT04410406	COMPLETED	Lymphatic Filariasis	Washington University School of Medicine	2020-08-20	PHASE3

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Moxidectin Parasite inhibitor

Chemical Structure

Molecular Weight: 639.82