For research use only.
Catalog No.S4287 Synonyms: FK463 Sodium, Mycamine Sodium
CAS No. 208538-73-2
Micafungin Sodium (FK463, Mycamine) is an inhibitor of 1, 3-beta-D-glucan synthesis, used as an antifungal drug.
Selleck's Micafungin Sodium has been cited by 7 publications
3 Customer Reviews
Effect of Micafungin on erythrocyte forward scatter. A. Original histogram of forward scatter of erythrocytes following exposure for 48 hours to Ringer solution without (grey area) and with (black line) presense of 25 µg/ml Micafungin. B. Arithmetic means ± SEM (n = 14) of the erythrocyte forward scatter (FSC) following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Micafungin (10-25 µg/ml). C. Arithmetic means ± SEM (n = 14) of the percentage of erythrocytes with forward scatter(FSC) <200 following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Micafungin (10-25 µg/ml). D. Arithmetic means ± SEM (n = 14) of the percentage of erythrocytes with forward scatter (FSC) >800 following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Micafungin (10-25 µg/ml). ***(p<0.001) indicates significant difference from the absence of Micafungin (ANOVA).
Cell Physiol Biochem, 2016, 584-95. Micafungin Sodium purchased from Selleck.
Micafungin potently inhibits EV71 proliferation in LLC-MK2 Derivative cells. LLC-MK2 Derivative cells were infected with EV71 (100 CCID50) and immediately treated with increasing concentrations of micafungin. Twenty hours post-infection, dsRNAs were stained by using specific antibody and visualized by FITC-conjugated secondary antibody (green). Nuclear DNA was also visualized by DAPI staining (blue).
Virol J, 2016, 13(1):99.. Micafungin Sodium purchased from Selleck.
Purity & Quality Control
Choose Selective Fungal Inhibitors
|Description||Micafungin Sodium (FK463, Mycamine) is an inhibitor of 1, 3-beta-D-glucan synthesis, used as an antifungal drug.|
Micafungin is an antifungal agent that does not inhibit bacteria. Although micafungin does not inhibit the bacteria directly, it does promote the survival of G. mellonella. Micafungin inhibits biofilm formation by impeding 1,3-β-D-glucan synthesis in Candida albicans.
|In vitro||Water||100 mg/mL (77.38 mM)|
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
|Storage||3 years -20°C(in the dark) powder
2 years -80°C(in the dark) in solvent
|Synonyms||FK463 Sodium, Mycamine Sodium|
In vivo Formulation Calculator (Clear solution)
|Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)|
|Dosage||mg/kg||Average weight of animals||g||Dosing volume per animal||ul||Number of animals|
|Step 2: Enter the in vivo formulation ()|
|% DMSO % % Tween 80 % ddH2O|
Working concentration： mg/ml；
Method for preparing DMSO master liquid: ： mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL，)
Method for preparing in vivo formulation：Take μL DMSO master liquid, next addμL PEG300， mix and clarify, next addμL Tween 80，mix and clarify, next add μL ddH2O，mix and clarify.
1.Please make sure the liquid is clear before adding the next solvent.
2.Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
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This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )
* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).
Molecular Weight Calculator
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Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
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