IXA4

Catalog No.S9797

For research use only.

IXA4, a highly selective, non-toxic IRE1/XBP1s activator, activates IRE1/XBP1s signaling without globally activating the unfolded protein response (UPR) or other stress-responsive signaling pathways, and reduces secretion of amyloid precursor protein (APP) through IRE1 activation, preventing APP-associated mitochondrial dysfunction.

IXA4 Chemical Structure

CAS No. 1185329-96-7

Purity & Quality Control

Choose Selective IRE1 Inhibitors

Biological Activity

Description IXA4, a highly selective, non-toxic IRE1/XBP1s activator, activates IRE1/XBP1s signaling without globally activating the unfolded protein response (UPR) or other stress-responsive signaling pathways, and reduces secretion of amyloid precursor protein (APP) through IRE1 activation, preventing APP-associated mitochondrial dysfunction.
Targets
IRE1/XBP1s [1]

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 436.5
Formula

C24H28N4O4

CAS No. 1185329-96-7
Storage 3 years -20°C powder
2 years -80°C in solvent

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