BI-D1870

Catalog No.S2843

BI-D1870 Chemical Structure

Molecular Weight(MW): 391.42

BI-D1870 is an ATP-competitive inhibitor of S6 ribosome for RSK1/2/3/4 with IC50 of 31 nM/24 nM/18 nM/15 nM in cell-free assays, respectively; 10- to 100-fold selectivity for RSK than MST2, GSK-3β, MARK3, CK1 and Aurora B.

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Cited by 6 Publications

4 Customer Reviews

  • Expressions of active forms of all p90RSK isoforms were assessed by immunoblotting in Control vs. GR cells following treatment with increasing concentrations of BI-D1870 for 24 hours. Actin was included as a loading control.

    Mol Cancer Ther, 2017, 16(5):793-804. BI-D1870 purchased from Selleck.

    (g) Changes of UBE2R1 expression in cells treated with an RSK inhibitor, BI-D1870, for 6 h.

    Sci Rep, 2016, 6:36134.. BI-D1870 purchased from Selleck.

  • HeLa cells were serum starved for 24 h, and then were treated with MK2206 (1 μM), rapamycin (Rapa; 100 nM), PP242 (1 μM), BEZ235 (0.5 μM), U0126 (U0; 15 μM), BI-D1870 (BI; 10 μM), GNE-652 (1 μM), AZD1208 (3 μM), and the indicated inhibitor combinations for 3 h before insulin (1 g/ml) was added for an additional 30 min. Cell lysates were analyzed by immunoblot assays using the indicated antibodies.

    Mol Cell Biol, 2014, 34(13): 2517-32. BI-D1870 purchased from Selleck.

    Serum-starved N41/OX1R cells were treated with 50 nM orexin-A for 1 h with or without 1 or 10 μM BI-D1870. Phosphorylation of S6K and S6 as well as MEK1/2, RSK, and Erk1/2 were evaluated by Western blotting.

    J Biol Chem, 2014, 289(46): 31950-9. BI-D1870 purchased from Selleck.

Purity & Quality Control

Choose Selective S6 Kinase Inhibitors

Biological Activity

Description BI-D1870 is an ATP-competitive inhibitor of S6 ribosome for RSK1/2/3/4 with IC50 of 31 nM/24 nM/18 nM/15 nM in cell-free assays, respectively; 10- to 100-fold selectivity for RSK than MST2, GSK-3β, MARK3, CK1 and Aurora B.
Targets
RSK4 [1]
(Cell-free assay)
RSK3 [1]
(Cell-free assay)
RSK2 [1]
(Cell-free assay)
RSK1 [1]
(Cell-free assay)
15 nM 18 nM 24 nM 31 nM
In vitro

BI-D1870 inhibits RSK1, RSK2, RSK3 and RSK4 with an IC50 of 10–30 nM, but does not significantly inhibit ten other AGC kinase members and over 40 other protein kinases tested at 100-fold higher concentrations. BI-D1870 is cell permeant and prevents the RSK-mediated phorbol ester- and EGF -induced phosphorylation of glycogen synthase kinase-3β and LKB1 in human embry-onic kidney 293 cells and Rat-2 cells. BI-D1870 does not affect the agonist-triggered phosphorylation of substrates for six other AGC kinases. Moreover, BI-D1870 does not suppress the phorbol ester- or EGF-induced phosphorylation of CREB. [1]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
EW-3 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGP1VmVKSzVyPUCuNFM2QCEQvF2= MVrTRW5ITVJ?
H9 NXXn[m4zT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmDQTWM2OD1yLkC2NFE6KM7:TR?= MoG2V2FPT0WU
KARPAS-45 NXrjRWVOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mn;zTWM2OD1yLkG2OVI2KM7:TR?= NUTxWJJRW0GQR1XS
NCI-H720 MnS0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoTmTWM2OD1yLkG3NVk1KM7:TR?= M2\lNHNCVkeHUh?=
CTV-1 MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXXJR|UxRTBwNEe4O|Ih|ryP M3nHUXNCVkeHUh?=
DU-4475 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnjCTWM2OD1yLkWwOFE4KM7:TR?= MkL1V2FPT0WU
A172 MmHaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWDJR|UxRTBwNUG3NFUh|ryP M{\5b3NCVkeHUh?=
EW-18 NHzlSVZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnzkTWM2OD1yLk[yNlEyKM7:TR?= M2i1T3NCVkeHUh?=
KU812 NFrIOIxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoXsTWM2OD1yLk[yOlI{KM7:TR?= NFPiR4JUSU6JRWK=
KP-N-YS MlSxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV7JR|UxRTBwNkiyNlMh|ryP MV\TRW5ITVJ?
SBC-1 MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXTJR|UxRTBwNkm1NlQh|ryP NF\h[mpUSU6JRWK=
ECC10 M3u4RWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mk[4TWM2OD1yLkewNFk1KM7:TR?= NI\OeZRUSU6JRWK=
GAMG NHnaeW5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{nJW2lEPTB;MD63OFcyPyEQvF2= NXLDUIhpW0GQR1XS
NCI-H209 Ml:zS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXjJR|UxRTBwN{[4NkDPxE1? NW\Xb5BvW0GQR1XS
MC-IXC Mmj3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV3acnpiUUN3ME2wMlc6PTh7IN88US=> MnjjV2FPT0WU
HSC-3 MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXrpZpQ4UUN3ME2wMlgyPzZ7IN88US=> MULTRW5ITVJ?
IST-SL1 NH63WoJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXLJR|UxRTBwOES1O|Qh|ryP MULTRW5ITVJ?
LU-139 MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVzvNohrUUN3ME2wMlg1QTV6IN88US=> M3;kO3NCVkeHUh?=
ML-2 MnvuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUL1SVJHUUN3ME2wMlg2PTd3IN88US=> NXLoN4t1W0GQR1XS
CAL-62 M122cWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnL4TWM2OD1yLki4NVUzKM7:TR?= MmmxV2FPT0WU
HL-60 M1jQVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVXJR|UxRTBwOEizOlIh|ryP M2joTHNCVkeHUh?=
KY821 NYrCZWprT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXi4c3FkUUN3ME2wMlg5QDF{IN88US=> NU\nRWtsW0GQR1XS
ES7 M4[0WWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVvLVZZuUUN3ME2wMlkyPjB5IN88US=> M1;1[3NCVkeHUh?=
MV-4-11 NYL4fINvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGjBVWJKSzVyPUCuPVc5QTdizszN M1HsWXNCVkeHUh?=
Daoy Mn3rS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYnMXYhHUUN3ME2wMlk5PzZ5IN88US=> M2focXNCVkeHUh?=
EoL-1-cell MmjHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1PQSWlEPTB;MT6wNVg4QCEQvF2= MmDhV2FPT0WU
TGW M1zubmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV;zOJpyUUN3ME2xMlA2OTJ2IN88US=> M4X6TXNCVkeHUh?=
LAMA-84 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWrJR|UxRTFwMUK3PVQh|ryP MlrRV2FPT0WU
KOSC-2 M1L6TWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIPFdWNKSzVyPUGuNVM{QDVizszN NF3OT2xUSU6JRWK=
A549 M{PhZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3Pi[GlEPTB;MT6zNFk2PSEQvF2= NFT2T|dUSU6JRWK=
CTB-1 MoTtS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHnse3BKSzVyPUGuOFQ3PzlizszN MkX1V2FPT0WU
NCI-H292 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFvodYFKSzVyPUGuOFYxPjlizszN NV3Pb3RvW0GQR1XS
LoVo M3TVOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWn2[GF7UUN3ME2xMlQ3PzV3IN88US=> M4q3OHNCVkeHUh?=
BFTC-905 NV\HSnh7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXfYTVdwUUN3ME2xMlU3OzN{IN88US=> MXzTRW5ITVJ?
BE-13 M3H6TGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVjJR|UxRTFwNUi3NFkh|ryP M3rESXNCVkeHUh?=
KE-37 NXXhXHFbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MY\JR|UxRTFwNUm0O|gh|ryP NV[zXnpjW0GQR1XS
HN MnjPS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGnZXVVKSzVyPUGuOlE{PjhizszN M1XFc3NCVkeHUh?=
A3-KAW MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXzJR|UxRTFwNkK4N|Qh|ryP M4faZ3NCVkeHUh?=
NEC8 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M17tbGlEPTB;MT63NFEyPSEQvF2= M4HFPXNCVkeHUh?=
Ramos-2G6-4C10 M2G2dWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUnJR|UxRTFwN{C0OFQh|ryP NX3qNXoyW0GQR1XS
NB10 MkDoS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkjJTWM2OD1zLke3OlMh|ryP MnzIV2FPT0WU
NBsusSR MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnvCTWM2OD1zLkiyPVYyKM7:TR?= MXfTRW5ITVJ?
ES4 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoHITWM2OD1zLki1NVQ{KM7:TR?= NH\QUmdUSU6JRWK=
ES8 M3jVUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYHJR|UxRTFwOEe3NlQh|ryP M{PLPHNCVkeHUh?=
CHL-1 NV7pRYpFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4f2VGlEPTB;MT65OVc6OiEQvF2= MYfTRW5ITVJ?
NCI-H2029 MmLwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF;6dGhKSzVyPUGuPVczPDFizszN M4HUcHNCVkeHUh?=
YKG-1 M2CzZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVfWSZhLUUN3ME2xMlk5PDN{IN88US=> MoPyV2FPT0WU
BV-173 M4XLW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVTJR|UxRTFwOUi2OlYh|ryP MUDTRW5ITVJ?
697 NHe4XopIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M123fWlEPTB;Mj6wNlIzQCEQvF2= NETq[|RUSU6JRWK=
SK-NEP-1 MnznS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnrRTWM2OD1{LkC0OEDPxE1? NWrrVFIxW0GQR1XS
LOXIMVI M2KyWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHnTfmhKSzVyPUKuNFQ1OzRizszN MknOV2FPT0WU
QIMR-WIL MkTYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3fNfWlEPTB;Mj6wO|g1QSEQvF2= Mo[zV2FPT0WU
DU-145 NXfGT4p{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV3HPFRjUUN3ME2yMlEyODV4IN88US=> NV:5bZVqW0GQR1XS
NB14 NFTqWY1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmXwTWM2OD1{LkGxN|IyKM7:TR?= NI\we3lUSU6JRWK=
G-361 NYTzWYlZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4TZbmlEPTB;Mj6xNlIyKM7:TR?= M3r5bXNCVkeHUh?=
BPH-1 M2\rNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEPXO5RKSzVyPUKuNVI6PTdizszN MX3TRW5ITVJ?
KYSE-150 NVu4[HV3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1TzRmlEPTB;Mj6xOVI{PCEQvF2= MlfjV2FPT0WU
HMV-II M3u4S2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{[1RWlEPTB;Mj6xOlY{OyEQvF2= Ml;HV2FPT0WU
TE-9 MlTuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGXlS5ZKSzVyPUKuNVc{PzZizszN M2XGcnNCVkeHUh?=
8-MG-BA NW[1b4VPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFnIRWxKSzVyPUKuNlM1PjFizszN MlTCV2FPT0WU
ES5 NVX5TWJ5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXXWS3B5UUN3ME2yMlI{PjN|IN88US=> NE\ndIpUSU6JRWK=
D-283MED MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFr3XmlKSzVyPUKuNlM3QTVizszN M4fqfXNCVkeHUh?=
SK-N-AS NXKxcGx[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYLYTHBsUUN3ME2yMlI6ODV7IN88US=> MX3TRW5ITVJ?
SW1710 NEm3T2JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIjlUYJKSzVyPUKuN|A3PjFizszN NUDteHdCW0GQR1XS
GCT NXrzWllyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH7NNIdKSzVyPUKuN|E{PThizszN M1u2dHNCVkeHUh?=
AGS NY[3R4xNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NE\TR2dKSzVyPUKuN|Q1ODRizszN NFnW[5dUSU6JRWK=
HuO9 NVO1dFh1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVfoPFJ{UUN3ME2yMlM3QDJ2IN88US=> MV7TRW5ITVJ?
MN-60 NUjIfFNjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYTySGJbUUN3ME2yMlQ1QDh|IN88US=> NEL5RphUSU6JRWK=
NB6 MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXPJR|UxRTJwNEW3O|kh|ryP NYKyfYZ5W0GQR1XS
NCI-H1395 MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2XrWWlEPTB;Mj60O|EzOSEQvF2= NYjhS2RjW0GQR1XS
H4 MkjwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHrWSmlKSzVyPUKuOFg{QTNizszN M{PnZ3NCVkeHUh?=
HT-3 NXXhW4piT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX3GWJc6UUN3ME2yMlUyODJ2IN88US=> NGTPRnpUSU6JRWK=
P12-ICHIKAWA NX:xVo9DT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3HGUmlEPTB;Mj61NlU2QSEQvF2= Mlq1V2FPT0WU
COLO-800 NVLtPJRkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYTJR|UxRTJwNUSxOlYh|ryP MYXTRW5ITVJ?
DB MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mlr1TWM2OD1{LkW1NFE{KM7:TR?= NIHzdIJUSU6JRWK=
LCLC-97TM1 NVjY[WxnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mmn6TWM2OD1{Lk[wNFI5KM7:TR?= NEDvVIhUSU6JRWK=
Ca9-22 NVfHZmQ1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVvaW3B6UUN3ME2yMlY2QTN|IN88US=> MYHTRW5ITVJ?
Becker NX;GO5o5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1jLTWlEPTB;Mj62OlA4QCEQvF2= NF31[pNUSU6JRWK=
ACN MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MljPTWM2OD1{Lk[2O|kh|ryP MYXTRW5ITVJ?
SJSA-1 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3;aOWlEPTB;Mj62Olg4KM7:TR?= MXHTRW5ITVJ?
NCI-H1048 MmLwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHvLTlNKSzVyPUKuOlg{OjFizszN M{W5dnNCVkeHUh?=
HEL NGnPXWlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2GwbmlEPTB;Mj63NFI2PCEQvF2= NUPURWlMW0GQR1XS
NCI-H69 NXf5fohjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFHpN3RKSzVyPUKuO|E3ODFizszN NWixOFZvW0GQR1XS
639-V MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3Tse2lEPTB;Mj63NVcxOyEQvF2= NWPaZlFMW0GQR1XS
U251 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX3WWZRMUUN3ME2yMlc{ODN{IN88US=> M1TmVHNCVkeHUh?=
NCI-H1792 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFfxeVNKSzVyPUKuO|M4OzhizszN MoXGV2FPT0WU
EW-1 MmDFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWHJR|UxRTJwN{WzNlgh|ryP MWHTRW5ITVJ?
ME-180 MoOwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXnJR|UxRTJwN{e3N|Yh|ryP NUWyUJRxW0GQR1XS
HH MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1[0WmlEPTB;Mj64NFAxOSEQvF2= NUHwcIdzW0GQR1XS
SW954 M{Toemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVLVZ3BRUUN3ME2yMlg2QDNizszN NYD5dnoxW0GQR1XS
SF268 NF7R[GNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoDCTWM2OD1{Lki3NlI2KM7:TR?= NIjzfmdUSU6JRWK=
D-566MG NGK0RYZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWfJR|UxRTJwOUGyPVUh|ryP NELvUW9USU6JRWK=
EM-2 NVjDbldXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoKxTWM2OD1{LkmyNVk{KM7:TR?= MoTLV2FPT0WU
NCI-H1299 M{TNbWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MULJR|UxRTJwOUO3N|Yh|ryP M4PRPHNCVkeHUh?=
PSN1 MoPJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVX6fHNMUUN3ME2zMlA2Pzh4IN88US=> M1jpUXNCVkeHUh?=
JVM-3 NGDRXHRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1jSOmlEPTB;Mz6wOlc2PiEQvF2= Ml;CV2FPT0WU
D-502MG NFPVNlVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVXJR|UxRTNwMEewNVkh|ryP MYHTRW5ITVJ?
SCC-4 NILHVGNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVrJR|UxRTNwMEmyO|Yh|ryP NYn3S455W0GQR1XS
GMS-10 NUfQeVl7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4rlR2lEPTB;Mz6wPVM5QCEQvF2= NIDHZXhUSU6JRWK=
A427 NX\BR2F5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NE\pdIpKSzVyPUOuNVA5PzNizszN NGDISJhUSU6JRWK=
NH-12 NXrJZ3lCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmXOTWM2OD1|LkGxOFU3KM7:TR?= MXzTRW5ITVJ?
KM12 NE\JSYNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWrJR|UxRTNwMUKyO|Mh|ryP MonVV2FPT0WU
GI-1 M2TYOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4f6UGlEPTB;Mz6xOVI2PSEQvF2= NFv0VolUSU6JRWK=
TE-8 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmLsTWM2OD1|LkG5NlMyKM7:TR?= NHv1cXRUSU6JRWK=
MKN1 Mm\yS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXXwUIhsUUN3ME2zMlIxQDd3IN88US=> NV25NVFUW0GQR1XS
NCI-H810 M2ToNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MU\JR|UxRTNwMkKxOVUh|ryP NEXIOpVUSU6JRWK=
GOTO NET1OYRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXH2eWZSUUN3ME2zMlI5ODB2IN88US=> NXHOV29wW0GQR1XS
T98G M3LSOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MofTTWM2OD1|LkK4NlE3KM7:TR?= M{Tkc3NCVkeHUh?=
HD-MY-Z M1[2NGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVvJR|UxRTNwM{[1OFIh|ryP MUXTRW5ITVJ?
SNU-C2B NXryXYI1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlzyTWM2OD1|LkO5NFk4KM7:TR?= MoOxV2FPT0WU
MOLT-4 NXL6SnZKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX7JR|UxRTNwM{mwPVgh|ryP M3nydnNCVkeHUh?=
RPMI-7951 MnHYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYHOOXA6UUN3ME2zMlM6PzNizszN NHzlTVRUSU6JRWK=
EW-11 MnnhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn\OTWM2OD1|LkSxNlI1KM7:TR?= NUPqcm1CW0GQR1XS
RD M2\2cmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2nVZWlEPTB;Mz60N|E{OiEQvF2= M2HQc3NCVkeHUh?=
SW48 NELhV2ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmL4TWM2OD1|LkSzN|U5KM7:TR?= Mki3V2FPT0WU
BB65-RCC NHfDVnBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFjLOHRKSzVyPUOuOFU{QTZizszN NFPmO5dUSU6JRWK=
Ca-Ski MmrpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mnr1TWM2OD1|LkS3OVE1KM7:TR?= M1nETXNCVkeHUh?=
CHP-134 MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUTJR|UxRTNwNEi3OVgh|ryP NFfxempUSU6JRWK=
CAL-33 NV\Jc2hET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlPrTWM2OD1|LkWzN|YzKM7:TR?= NWPyT2d{W0GQR1XS
TYK-nu NF;sUmtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHXsW|RKSzVyPUOuOVM3PzZizszN M{jxb3NCVkeHUh?=
LB831-BLC MlHTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlG5TWM2OD1|LkW0NFE3KM7:TR?= M{LYWXNCVkeHUh?=
KU-19-19 NFX5bFRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoW5TWM2OD1|Lk[wN|A1KM7:TR?= MlztV2FPT0WU
KG-1 NG\DZXdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVvoOVhuUUN3ME2zMlYyOTB4IN88US=> MW\TRW5ITVJ?
COLO-829 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUW5Z3E{UUN3ME2zMlY3PjF6IN88US=> M3L2PHNCVkeHUh?=
HUTU-80 M2HpWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVfJR|UxRTNwNk[2NlEh|ryP NEH5co1USU6JRWK=
NCI-H446 M2SwXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVfuXpVUUUN3ME2zMlY5OzRizszN MlHqV2FPT0WU
LB2241-RCC NUDkWXNnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH6zRXRKSzVyPUOuOlg3OjVizszN M{e4UnNCVkeHUh?=
JEG-3 M4fNNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYrteIMyUUN3ME2zMlY6OTlizszN M3XIWnNCVkeHUh?=
LNCaP-Clone-FGC MnfaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWLJR|UxRTNwN{CwOFEh|ryP NXm2XpNxW0GQR1XS
M059J Ml3TS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF;jSJNKSzVyPUOuO|E1PjhizszN NHzNZm5USU6JRWK=
SK-MES-1 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF75XJFKSzVyPUOuO|MxOyEQvF2= MXTTRW5ITVJ?
GT3TKB NGPuOIZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3\HfWlEPTB;Mz63OVYxPCEQvF2= MVHTRW5ITVJ?
DOK MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkHaTWM2OD1|Lke2OVI3KM7:TR?= NW\VTJdJW0GQR1XS
HO-1-N-1 MojxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3HHWGlEPTB;Mz63PVgxOSEQvF2= NF\OZWhUSU6JRWK=
MZ1-PC M3q2c2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWnJR|UxRTNwOEK4PFMh|ryP MojGV2FPT0WU
8305C NH;TdYNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFzCWI9KSzVyPUOuPFg6PDNizszN MmjPV2FPT0WU
CGTH-W-1 M4\2[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{KyPWlEPTB;Mz65N|UxPCEQvF2= NVjiWIVUW0GQR1XS
LU-134-A Mnz3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFfKXJBKSzVyPUOuPVU1OjJizszN Mn\0V2FPT0WU
C32 M3H3Z2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUjtUpU{UUN3ME2zMlk3PThzIN88US=> MYnTRW5ITVJ?
MOLT-13 NWTIUVFCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUnFTItXUUN3ME2zMlk3QDV4IN88US=> M1:yfnNCVkeHUh?=
A375 NIXYZlhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlPXTWM2OD12LkC1NVYzKM7:TR?= MYHTRW5ITVJ?
CAL-12T MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1PUU2lEPTB;ND6wOVc6PSEQvF2= NV;XXmpWW0GQR1XS
IGR-1 NFPUc2dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIrST3JKSzVyPUSuNVAzPzRizszN MVzTRW5ITVJ?
LB1047-RCC NVfl[2xDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYDJR|UxRTRwMUC0OFEh|ryP MYHTRW5ITVJ?
BHT-101 NFG2[|NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mnj5TWM2OD12LkGwOlg{KM7:TR?= MVTTRW5ITVJ?
A431 NF3xRXZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUXJR|UxRTRwMUSwPFEh|ryP MWTTRW5ITVJ?
EPLC-272H MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn3KTWM2OD12LkG3OVk3KM7:TR?= NIjSZ3pUSU6JRWK=
HT-1376 NUfKPJk{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEXIdXRKSzVyPUSuNlMxPTlizszN MXrTRW5ITVJ?
HCC1954 NY\R[o9kT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYXJR|UxRTRwMkW3OFYh|ryP NYe5[XNHW0GQR1XS
KYSE-510 M1fBUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmPxTWM2OD12LkK2NFkh|ryP NGDlWnhUSU6JRWK=
PANC-03-27 NHTYTFNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4T1b2lEPTB;ND6zNFA5OyEQvF2= NIDqNFdUSU6JRWK=
MDA-MB-157 M4jBPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3fn[2lEPTB;ND6zNFY2PiEQvF2= M4X2PXNCVkeHUh?=
HOP-62 NFrHe3VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mm\yTWM2OD12LkOwPFU3KM7:TR?= MlvqV2FPT0WU
ETK-1 MlX4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mmm5TWM2OD12LkO2NlA{KM7:TR?= M3LUSnNCVkeHUh?=
MIA-PaCa-2 NIDzRlNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4HrSWlEPTB;ND6zOlIzPyEQvF2= NUDSWYFLW0GQR1XS
MHH-PREB-1 NWfpRVBiT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlS1TWM2OD12LkO5O|c{KM7:TR?= M3\zUnNCVkeHUh?=
LXF-289 M2\XUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVHVTGdbUUN3ME20MlQxOjB{IN88US=> NEHNSHlUSU6JRWK=
ATN-1 Mn\PS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYe4fmN3UUN3ME20MlQzOzRzIN88US=> MVjTRW5ITVJ?
8505C MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGDQdnBKSzVyPUSuOFU5OjVizszN NUXUcYJ2W0GQR1XS
HOS NH3UflBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NITPd3FKSzVyPUSuOFY1PTNizszN M3\0ZXNCVkeHUh?=
U-266 MlrXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEDqeo1KSzVyPUSuOlExOzJizszN NGfxZ4ZUSU6JRWK=
5637 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3P1NGlEPTB;ND62NVQ1PCEQvF2= NEDJS3RUSU6JRWK=
GCIY MmHSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWLJR|UxRTRwN{GwNVUh|ryP M4GwU3NCVkeHUh?=
MDA-MB-231 NG\Je5RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnjTTWM2OD12LkeyNVE2KM7:TR?= MkPlV2FPT0WU
RKO NUWyV3NCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVPJR|UxRTRwN{K4NVch|ryP NH2zbGpUSU6JRWK=
COR-L23 NHLHT5VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{nPNGlEPTB;ND63OFI2PiEQvF2= NFHkWHBUSU6JRWK=
DJM-1 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWXJR|UxRTRwN{m3Nlkh|ryP MVvTRW5ITVJ?
D-423MG M1vVTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGm0bnBKSzVyPUSuPFA5ODNizszN NWDQXpBPW0GQR1XS
DMS-114 NUHvcG5pT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHT1cZNKSzVyPUSuPFE{QDZizszN MVLTRW5ITVJ?
MHH-ES-1 MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkXnTWM2OD12LkiyOVA1KM7:TR?= Mli2V2FPT0WU
CAL-51 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHfyW|JKSzVyPUSuPFY5PDNizszN M3TiTXNCVkeHUh?=
SW626 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkHqTWM2OD12Lki5Olk4KM7:TR?= NHjtO25USU6JRWK=
COLO-824 NYHaOZlQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUG5VJBvUUN3ME20MlkxPDB6IN88US=> MWHTRW5ITVJ?
NCI-H1437 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYXsUZplUUN3ME20MlkzQTNizszN M4TIVHNCVkeHUh?=
CAL-39 MnTMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYjJR|UxRTRwOUO5PFgh|ryP MVPTRW5ITVJ?
PC-3 NGDnTIdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkPrTWM2OD12Lkm0OlQ5KM7:TR?= Ml6zV2FPT0WU
A101D MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{nZc2lEPTB;ND65Olg3PSEQvF2= NXvrVHFVW0GQR1XS
ES1 NUfRfnlGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXXsVZJZUUN3ME21MlAxOTNizszN MYjTRW5ITVJ?
TE-1 M3iwRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXTJR|UxRTVwMEO2OlYh|ryP NHrIU4hUSU6JRWK=
KP-N-YN M3XnWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M321b2lEPTB;NT6wOVY4KM7:TR?= NF34XlNUSU6JRWK=
EFO-27 MlmwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYrJR3p5UUN3ME21MlA3OzJ7IN88US=> MUnTRW5ITVJ?
BT-549 M1LVeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVXw[JF6UUN3ME21MlA4PzN4IN88US=> NFH2PGdUSU6JRWK=
HLE MnHNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUPJR|UxRTVwMUG3N|Qh|ryP Mlf4V2FPT0WU
SW982 M4iyU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYHJR|UxRTVwMUOzO|Qh|ryP M17WSnNCVkeHUh?=
SCC-25 MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV\JR|UxRTVwMUmwOFYh|ryP NFT4dG5USU6JRWK=
SK-MEL-28 M4\NPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGnXdotKSzVyPUWuNlA{OTNizszN NIjwXFRUSU6JRWK=
CaR-1 M2fHUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2PCdmlEPTB;NT6yNFczPiEQvF2= MnjOV2FPT0WU
MLMA MlTuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYO1cJVTUUN3ME21MlI{PDN4IN88US=> MnjyV2FPT0WU
VM-CUB-1 NF3DSGFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn\6TWM2OD13LkKzOFM6KM7:TR?= NI\kVJFUSU6JRWK=
KNS-42 NVnSc29UT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4\CTWlEPTB;NT6yOlE3KM7:TR?= NEHaVWpUSU6JRWK=
TK10 MnLOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV\JR|UxRTVwM{[wPFYh|ryP NYHGTmxvW0GQR1XS
MEG-01 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlnxTWM2OD13LkO2Nlc1KM7:TR?= NH;0blZUSU6JRWK=
DEL MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoflTWM2OD13LkO5NFI{KM7:TR?= NHP3No1USU6JRWK=
SJRH30 Mk\mS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFrTXpNKSzVyPUWuN|kzOTNizszN MkT5V2FPT0WU
SK-PN-DW MmfkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmrlTWM2OD13LkSzOVg6KM7:TR?= Mn73V2FPT0WU
TE-10 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV3JR|UxRTVwNES4PVMh|ryP M{K5XXNCVkeHUh?=
KNS-81-FD MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3H0fGlEPTB;NT61NFA6OiEQvF2= NWrEcI1TW0GQR1XS
BHY NWnodVY4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVPlRlJXUUN3ME21MlUyODdizszN NXPYV4d2W0GQR1XS
KYSE-270 MlS2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFzNNphKSzVyPUWuOVM2OzZizszN MljWV2FPT0WU
NCI-H650 MmT2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmnVTWM2OD13LkW3NVE1KM7:TR?= MoDMV2FPT0WU
L-363 Ml3rS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MofWTWM2OD13Lk[5OFc3KM7:TR?= NGqwdW9USU6JRWK=
TCCSUP NF7QPWdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGS0NJdKSzVyPUWuO|E4PzhizszN M3;ZZnNCVkeHUh?=
SCH MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYG0UHp2UUN3ME21Mlc1PzZ5IN88US=> M4DnfXNCVkeHUh?=
HTC-C3 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGey[XVKSzVyPUWuO|c3PDRizszN MUTTRW5ITVJ?
J-RT3-T3-5 M4LBfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4X0XmlEPTB;NT64NFc6PCEQvF2= NWr0ZZR{W0GQR1XS
Hs-578-T MojQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWrJR|UxRTVwOEO2NFch|ryP NX;G[4tTW0GQR1XS
M14 NUX1bmliT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX7vXWNzUUN3ME21Mlg3PzJ4IN88US=> M2\0WXNCVkeHUh?=
HT-144 NYjBfmhqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVTJR|UxRTVwOE[4N|Ih|ryP MlvxV2FPT0WU
CAL-54 NXP1enNzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mn\ZTWM2OD13LkmzN|E1KM7:TR?= NXHyVYVOW0GQR1XS
T47D NHHIOnFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV3JR|UxRTVwOU[xNkDPxE1? NGLqWnNUSU6JRWK=
GB-1 M2TWSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{PEfGlEPTB;Nj6wNlA3QCEQvF2= MV;TRW5ITVJ?
HSC-2 M4DSNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NY\QVoZVUUN3ME22MlEzOzV|IN88US=> MXrTRW5ITVJ?
SiHa NXO1UHlHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M13Ge2lEPTB;Nj6xOFA6PyEQvF2= M{TRdHNCVkeHUh?=
OMC-1 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoXlTWM2OD14LkO1OFQyKM7:TR?= NUXZWGh7W0GQR1XS
HGC-27 M2HobWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3T3N2lEPTB;Nj6zOVc5PiEQvF2= NYS1c3lyW0GQR1XS
FTC-133 NELnSVNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVX0XHpGUUN3ME22MlQ3PTVzIN88US=> MYfTRW5ITVJ?
KS-1 NF\LW3JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4P6eWlEPTB;Nj61NlE1PyEQvF2= NEfBephUSU6JRWK=
HT-1080 MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3HGUmlEPTB;Nj61OFA1OiEQvF2= NIGzS2hUSU6JRWK=
SKG-IIIa NHOxdJZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3XJemlEPTB;Nj61OlI3OyEQvF2= NVTLcJAyW0GQR1XS
OCUB-M MlXWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWLJR|UxRTZwNkC3O{DPxE1? M{nWT3NCVkeHUh?=
MDA-MB-175-VII NELzSlhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVLJR|UxRTZwNkKwPUDPxE1? M1nCSHNCVkeHUh?=
BB30-HNC NWCxU5N{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGfnSIdKSzVyPU[uOlc1PDRizszN MmfZV2FPT0WU
D-542MG MlXRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlLITWM2OD14LkezNFkh|ryP NULvWlB3W0GQR1XS
NCI-H2405 M{fD[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWTJR|UxRTZwN{S4OVUh|ryP NFKzeY1USU6JRWK=
SW1573 MmnLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV\JR|UxRTZwN{izNVkh|ryP M4LHcnNCVkeHUh?=
NCI-SNU-1 M1LlWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NH6yWXdKSzVyPU[uO|kxOjJizszN M1nqbHNCVkeHUh?=
RT-112 NVTpcmk3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX7JR|UxRTZwN{m0OlMh|ryP M1LrV3NCVkeHUh?=
COR-L88 M2TMTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUTJR|UxRTZwN{m3PVEh|ryP M4LPXnNCVkeHUh?=
SCC-9 MnHuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{\ke2lEPTB;Nj64NlU2KM7:TR?= MUXTRW5ITVJ?
U-87-MG NIPSW29Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXOzNG42UUN3ME22Mlg{QDJ4IN88US=> M2rNS3NCVkeHUh?=
Detroit562 MlnlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2fxT2lEPTB;Nj64OVk6OSEQvF2= NIXY[mdUSU6JRWK=
LC-2-ad NELLclZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWPTOmFzUUN3ME22Mlg3Ojl{IN88US=> NXyzdoFpW0GQR1XS
IGROV-1 MlTLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFTOWmhKSzVyPU[uPVI2QDNizszN NEToTIlUSU6JRWK=
OVCAR-8 NYfBcHE{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2S3cGlEPTB;Nj65OFIzQSEQvF2= MYPTRW5ITVJ?
SNU-387 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mom4TWM2OD14Lkm5OVE3KM7:TR?= M4fFN3NCVkeHUh?=
TGBC1TKB MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHTOPIlKSzVyPUeuNVUzPzdizszN MoK2V2FPT0WU
NOS-1 MnixS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlzCTWM2OD15LkKwOFE2KM7:TR?= NFO3W5ZUSU6JRWK=
HEC-1 NH3RfIZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmL0TWM2OD15LkK1N|g4KM7:TR?= M17wRXNCVkeHUh?=
GI-ME-N NInVXIlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4G5UWlEPTB;Nz6yPVE2QCEQvF2= NHnmT4NUSU6JRWK=
KYSE-520 MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{DOXWlEPTB;Nz6yPVI6KM7:TR?= M1nOZnNCVkeHUh?=
SNU-423 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUHGNGpDUUN3ME23MlI6PDV{IN88US=> NGDjO49USU6JRWK=
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OVCAR-4 NXvGZlg3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{e5SmlEPTB;Nz61OVI3KM7:TR?= M4TBPXNCVkeHUh?=
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RS4-11 Mmi3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUHrfVl7UUN3ME23MlcxOTl4IN88US=> Mk[1V2FPT0WU
OVCAR-5 NWL2cHFJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWPJR|UxRTdwOEKzNlkh|ryP NFHwZo1USU6JRWK=
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NCI-H747 M{DXXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NX[4WGl3UUN3ME24MlA1PDV5IN88US=> MmL4V2FPT0WU
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NCI-H2122 MlvnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVOxZ4NpUUN3ME24MlQxPDd7IN88US=> MlXVV2FPT0WU
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NCI-H28 NGSxRW5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkjQTWM2OD16Lki1NVg2KM7:TR?= M173UXNCVkeHUh?=
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NB17 NHXnOFRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoP0TWM2OD17LkG0OVM2KM7:TR?= MYrTRW5ITVJ?
MOLT-16 NUXtZpRwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYPSRpRbUUN3ME25MlE3PjV3IN88US=> M3LPTXNCVkeHUh?=
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NB12 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUPJR|UxRTlwM{SwPFEh|ryP MWXTRW5ITVJ?
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KINGS-1 NULD[lIxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH3G[nNKSzVyPUmuOlk{PyEQvF2= NWrUZmduW0GQR1XS
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KYSE-410 M4eySGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXrlTnY2UUN3ME2xNE4xPjF3IN88US=> Mn;KV2FPT0WU
SK-MEL-2 MkTKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1;M[mlEPTB;MUCuNVU5QCEQvF2= NWK2cHpEW0GQR1XS
NB5 NFnLbpVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYfpW5JGUUN3ME2xNE42PDB3IN88US=> MXnTRW5ITVJ?
NTERA-S-cl-D1 MlXQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUfrTHoxUUN3ME2xNE42PDd3IN88US=> NWLCOYREW0GQR1XS
MZ2-MEL MnvhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{nNWmlEPTB;MUCuOlYzKM7:TR?= NETTVppUSU6JRWK=
SF539 NUjV[VFlT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYXJR|UxRTFyLkexPFgh|ryP NX\ITYlsW0GQR1XS
CAL-120 NIrK[o9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHXtPZFKSzVyPUGwMlc2QTdizszN NFHGVndUSU6JRWK=
GR-ST NIHCWVZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2CyT2lEPTB;MUGuNlk5KM7:TR?= MnrnV2FPT0WU
IA-LM MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{nibmlEPTB;MUGuN|Q5PiEQvF2= NH6zR49USU6JRWK=
NCI-H2452 M2fVZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1naW2lEPTB;MUGuN|kzPyEQvF2= MVHTRW5ITVJ?
NCI-H1648 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkHsTWM2OD1zMT60OlI6KM7:TR?= M3vpR3NCVkeHUh?=
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NCI-H2228 NHjYVXZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWn2d|VIUUN3ME2xNU41QTJ6IN88US=> MoLOV2FPT0WU
LN-405 MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1;TPWlEPTB;MUGuOVkzPyEQvF2= NWfPTXVrW0GQR1XS
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SK-HEP-1 NIXOOIRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVjJR|UxRTF{LkK2NVMh|ryP MnTsV2FPT0WU
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NCI-H1581 M3nSR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3rW[mlEPTB;MUKuNlgyQSEQvF2= Mn62V2FPT0WU
NCI-H23 MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4DJUGlEPTB;MUKuN|EzPSEQvF2= MnHtV2FPT0WU
NCI-H596 MoLjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVzs[lZxUUN3ME2xNk41Pzl6IN88US=> MnKyV2FPT0WU
NB69 NGTvfodIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYPJR|UxRTF{Lke1PFUh|ryP M13qTnNCVkeHUh?=
ChaGo-K-1 MlfQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnLLTWM2OD1zMj63OlQ6KM7:TR?= M1i2ZnNCVkeHUh?=
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MDA-MB-415 MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXHvOVBCUUN3ME2xN{4yPjB7IN88US=> M{TaOHNCVkeHUh?=
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NCI-H2009 Mnn6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MknJTWM2OD1zNj65NlY3KM7:TR?= NUHHe4U{W0GQR1XS
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MC116 NX3XZlZ3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmTqTWM2OD1zOT61N|MyKM7:TR?= NH74fJBUSU6JRWK=
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NCI-H82 MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVLJR|UxRTF7Lk[4O|gh|ryP MnXsV2FPT0WU
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HAL-01 M1vU[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEjHW4pKSzVyPUKyMlA1OThizszN M{XvUHNCVkeHUh?=
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CAL-85-1 M3H6WGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoexTWM2OD1{NT6xOVQ1KM7:TR?= MlP4V2FPT0WU
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NCI-H2347 M3jn[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NH;z[JlKSzVyPUK1MlQzPDlizszN MnP4V2FPT0WU
P30-OHK MkO1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NY\hW25pUUN3ME2yOU43OzF6IN88US=> MnrvV2FPT0WU
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CAMA-1 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV\JR|UxRTJ4LkS4O|Yh|ryP MoXiV2FPT0WU
MHH-NB-11 M3j6Umdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIPnO4lKSzVyPUK2MlU5PTFizszN MkHEV2FPT0WU
IST-MEL1 NYrzfWxQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlXLTWM2OD1{Nj63NVc4KM7:TR?= MXLTRW5ITVJ?
KARPAS-299 NX;XZm1ET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVnJR|UxRTJ5LkS3NFEh|ryP MX3TRW5ITVJ?
TE-11 NH3sT5hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1\RZmlEPTB;MkeuO|M1OiEQvF2= NU\5SoFKW0GQR1XS
769-P M2\hfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVfJR|UxRTJ6LkS1N|Mh|ryP MoO3V2FPT0WU
CAL-72 NF\PPGNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYf1U3c6UUN3ME2yPE42PTZzIN88US=> MWXTRW5ITVJ?
NCI-H2342 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVnJR|UxRTJ7LkO4NFMh|ryP MYnTRW5ITVJ?
NCI-H1651 NI\WWHpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M13sfGlEPTB;MkmuPFUxOyEQvF2= Mmi2V2FPT0WU
OE33 NFPMNIVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4\EV2lEPTB;M{CuNVM1OiEQvF2= NIHXN2tUSU6JRWK=
HuP-T4 MlPwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MY\JR|UxRTNzLkS4N|ch|ryP NXzvZWVvW0GQR1XS
U-118-MG MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIKxUmFKSzVyPUOyMlU1PDFizszN M1j6T3NCVkeHUh?=
SN12C NFLYWVlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M37kNWlEPTB;M{KuPFgyPSEQvF2= Mle0V2FPT0WU
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KM-H2 MmLsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX;JR|UxRTN|LkG2PVkh|ryP MYTTRW5ITVJ?
OVCAR-3 NXPxcFM5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MV;JR|UxRTN|LkSxNlch|ryP MmTrV2FPT0WU
NCI-H1304 NY\zfG5KT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mkn6TWM2OD1|Mz62NFM3KM7:TR?= Mn\iV2FPT0WU
LU-135 NXzId4NqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmTBTWM2OD1|Mz63NFg3KM7:TR?= M{L6dHNCVkeHUh?=
S-117 M1niXGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFvDU5dKSzVyPUOzMlczQDZizszN M3XtNHNCVkeHUh?=
NCI-H1755 NV7uTlFKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV;zWGFxUUN3ME2zN{45OTFizszN NU[wcHhKW0GQR1XS
Mo-T MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn\1TWM2OD1|Mz64OVk{KM7:TR?= NX[xNIpUW0GQR1XS
SK-OV-3 NWnCW3ZyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkezTWM2OD1|Mz64PFU1KM7:TR?= M1vJUHNCVkeHUh?=
RCC10RGB NV;RRVdVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWXLcZhFUUN3ME2zN{46PDN|IN88US=> NYX4eWJtW0GQR1XS
COLO-680N MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYjJR|UxRTN2LkGzPVch|ryP NE\yfIJUSU6JRWK=
KURAMOCHI NYfSe5VlT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF;OSHdKSzVyPUO0MlY1OjVizszN NXLOfottW0GQR1XS
NCI-H661 NIrFeFBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFXMOYZKSzVyPUO0Mlg1PDhizszN M2L6WHNCVkeHUh?=
YAPC MlfLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkLqTWM2OD1|NT65OVM{KM7:TR?= NVqzPYxEW0GQR1XS
NCI-H526 MlvyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWLJR|UxRTN5LkK3O|Ih|ryP M1\HOHNCVkeHUh?=
A498 NVXNZ2N5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1vBS2lEPTB;M{iuNFk2PCEQvF2= MmfVV2FPT0WU
VMRC-RCZ NUjKc3F[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NY\6fY95UUN3ME2zPU4xODV2IN88US=> MmnkV2FPT0WU
HCT-116 NHuwSHFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXHJR|UxRTN7LkC1PEDPxE1? MXvTRW5ITVJ?
COLO-320-HSR MnPrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mo\2TWM2OD12MD6wOFEh|ryP MVfTRW5ITVJ?
OAW-42 Mn;jS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2C0S2lEPTB;NECuNFU1OiEQvF2= NXLHPVRDW0GQR1XS
SK-MEL-1 M{\1SGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUjJR|UxRTRyLkK5Nlch|ryP MXHTRW5ITVJ?
IST-MES1 MmnYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIrUOoJKSzVyPUSwMlc3PTNizszN NUXER|ROW0GQR1XS
CP50-MEL-B NEjuPXRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnftTWM2OD12MT6wO|k4KM7:TR?= M{P4SXNCVkeHUh?=
RMG-I NWjrfZRiT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmrSTWM2OD12Mj60PVIyKM7:TR?= M4XXbnNCVkeHUh?=
D-336MG MlXvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlLtTWM2OD12Mz6xNVUzKM7:TR?= M{jJWHNCVkeHUh?=
SHP-77 M4\OeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUPJR|UxRTR|LkG4Nlgh|ryP NUjHeZk5W0GQR1XS
SW872 Mn\tS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NInxZ4pKSzVyPUSzMlIyOjNizszN NIDmRoZUSU6JRWK=
DBTRG-05MG NFnSW3BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVLR[Jl3UUN3ME20OE43QTl4IN88US=> MnnqV2FPT0WU
COLO-678 NFq5U4VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MULJR|UxRTR3LkewN|Ih|ryP NYq1T2ZFW0GQR1XS
EGI-1 NXTFfWRyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVfJR|UxRTR5LkG4N|Mh|ryP Ml:4V2FPT0WU
KYSE-70 NFzBblhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3\HT2lEPTB;NEeuO|IzOiEQvF2= Mm[wV2FPT0WU
BALL-1 Ml22S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkfaTWM2OD12Nz64NlU1KM7:TR?= NYTjVFdXW0GQR1XS
MDA-MB-361 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlnTTWM2OD12OD6wOFYh|ryP NXK4N|hjW0GQR1XS
NCI-H1838 NEf2PXBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{TpRWlEPTB;NEiuN|Q2QCEQvF2= NWnjVHZXW0GQR1XS
NCI-H1573 NXf3V2pbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF\OdoFKSzVyPUS4MlY4QDVizszN NXvnXmJWW0GQR1XS
HCC1395 Ml3RS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV\JR|UxRTR6Lkm5NkDPxE1? NWXsPHk2W0GQR1XS
NCI-H2291 MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmnOTWM2OD12OT61PVg5KM7:TR?= MVHTRW5ITVJ?
RH-18 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmjBTWM2OD13MD6wPFg1KM7:TR?= MWrTRW5ITVJ?

... Click to View More Cell Line Experimental Data

Protocol

Solubility (25°C)

In vitro DMSO 78 mg/mL (199.27 mM)
Water Insoluble
Ethanol Insoluble
In vivo Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
30% PEG400+0.5% Tween80+5% propylene glycol
For best results, use promptly after mixing.
30 mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 391.42
Formula

C19H23F2N5O2

CAS No. 501437-28-1
Storage powder
in solvent
Synonyms N/A

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field

Frequently Asked Questions

  • Question 1:

    BI-D1870 (catalog No.S2843) is found as a racemic mixture?

  • Answer:

    Yes, BI-D1870 (catalog No.S2843) is found as a racemic mixture.

S6 Kinase Signaling Pathway Map

Related S6 Kinase Products0

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID